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Musculoskeletal diseases, infections and vaccines : state of the art, research perspectives and educational needs

Ecarnot, Fiona ; Thiyagarajan, Jotheeswaran Amuthavalli ; Barbagallo, Mario ; Barratt, Jane ; Constantinescu, Stefan ; Elkayam, Ori ; Ferrucci, Luigi ; Hiligsmann, Mickaël ; Kapetanovic, Meliha LU and Macchia, Francesco , et al. (2025) In Aging clinical and experimental research 37(1).
Abstract

Musculoskeletal disorders are a significant public health burden concern, projected to increase in the coming decades, and will substantially contribute to the rising prevalence of functional impairment, frailty and disability in a growing global population. Since persons with musculoskeletal disorders tend to have immune dysfunction, inflammation or be taking immunosuppressive medication, prevention of vaccine-preventable diseases (VPDs) in this group is particularly important. The European Interdisciplinary Council for Aging (EICA) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) jointly convened a 2-day in-person and virtual meeting on 26–27 September... (More)

Musculoskeletal disorders are a significant public health burden concern, projected to increase in the coming decades, and will substantially contribute to the rising prevalence of functional impairment, frailty and disability in a growing global population. Since persons with musculoskeletal disorders tend to have immune dysfunction, inflammation or be taking immunosuppressive medication, prevention of vaccine-preventable diseases (VPDs) in this group is particularly important. The European Interdisciplinary Council for Aging (EICA) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) jointly convened a 2-day in-person and virtual meeting on 26–27 September 2023, to review the state of the evidence on the link between musculoskeletal diseases, infections and vaccines. We present here the Executive Summary of the proceedings of this meeting. We review the importance of physical activity in preventing or mitigating both musculoskeletal diseases and risk of infection. We summarize current knowledge of the impact of common VPDs on the development and progression of musculoskeletal diseases, and the role of selected vaccines in preventing onset and worsening of frailty and disability in these individuals. This report summarizes the evidence presented at the two-day meeting, highlighting the need to raise awareness among scientists, healthcare professionals, decision-makers, civil society and the general public about the long-term sequelae of VPDs, with focus on the health status of older patients with musculoskeletal diseases.

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type
Contribution to journal
publication status
published
subject
keywords
Infection, Musculoskeletal disease, Older adults, Vaccination
in
Aging clinical and experimental research
volume
37
issue
1
article number
46
publisher
Kurtis
external identifiers
  • scopus:85218679011
  • pmid:39985736
ISSN
1594-0667
DOI
10.1007/s40520-025-02940-w
language
English
LU publication?
yes
id
e715fe37-79c1-43c3-ab72-9ca69863db8c
date added to LUP
2025-06-10 08:54:28
date last changed
2025-07-08 11:51:10
@article{e715fe37-79c1-43c3-ab72-9ca69863db8c,
  abstract     = {{<p>Musculoskeletal disorders are a significant public health burden concern, projected to increase in the coming decades, and will substantially contribute to the rising prevalence of functional impairment, frailty and disability in a growing global population. Since persons with musculoskeletal disorders tend to have immune dysfunction, inflammation or be taking immunosuppressive medication, prevention of vaccine-preventable diseases (VPDs) in this group is particularly important. The European Interdisciplinary Council for Aging (EICA) and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) jointly convened a 2-day in-person and virtual meeting on 26–27 September 2023, to review the state of the evidence on the link between musculoskeletal diseases, infections and vaccines. We present here the Executive Summary of the proceedings of this meeting. We review the importance of physical activity in preventing or mitigating both musculoskeletal diseases and risk of infection. We summarize current knowledge of the impact of common VPDs on the development and progression of musculoskeletal diseases, and the role of selected vaccines in preventing onset and worsening of frailty and disability in these individuals. This report summarizes the evidence presented at the two-day meeting, highlighting the need to raise awareness among scientists, healthcare professionals, decision-makers, civil society and the general public about the long-term sequelae of VPDs, with focus on the health status of older patients with musculoskeletal diseases.</p>}},
  author       = {{Ecarnot, Fiona and Thiyagarajan, Jotheeswaran Amuthavalli and Barbagallo, Mario and Barratt, Jane and Constantinescu, Stefan and Elkayam, Ori and Ferrucci, Luigi and Hiligsmann, Mickaël and Kapetanovic, Meliha and Macchia, Francesco and Michel, Jean Pierre and Migliore, Alberto and Pilotto, Alberto and Sieber, Cornel and Strangfeld, Anja and Veronese, Nicola and Vetrano, Davide Liborio and Maggi, Stefania and Rizzoli, René}},
  issn         = {{1594-0667}},
  keywords     = {{Infection; Musculoskeletal disease; Older adults; Vaccination}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{Kurtis}},
  series       = {{Aging clinical and experimental research}},
  title        = {{Musculoskeletal diseases, infections and vaccines : state of the art, research perspectives and educational needs}},
  url          = {{http://dx.doi.org/10.1007/s40520-025-02940-w}},
  doi          = {{10.1007/s40520-025-02940-w}},
  volume       = {{37}},
  year         = {{2025}},
}