Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis
Franklin, Jonas LU ; Ingvarsson, T. ; Englund, Martin LU
and Lohmander, Stefan
LU
(2009)
In Annals of the Rheumatic Diseases
68(4).
p.536-540
- Abstract
- Objective: To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement. Methods: Case-control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invited to participate. First-degree relatives of participating patients served as controls. A total of 1473 patients ( 872 women) and 1103 controls ( 599 women), all born between 1910 and 1939 and who had answered a questionnaire including questions about height and weight, were analysed. A randomly selected sample, representative of the Icelandic population, was used as a secondary control group. Results: The OR, adjusted for age, occupation and... (More)
- Objective: To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement. Methods: Case-control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invited to participate. First-degree relatives of participating patients served as controls. A total of 1473 patients ( 872 women) and 1103 controls ( 599 women), all born between 1910 and 1939 and who had answered a questionnaire including questions about height and weight, were analysed. A randomly selected sample, representative of the Icelandic population, was used as a secondary control group. Results: The OR, adjusted for age, occupation and presence of hand OA, for having a THR was 1.1 (95% CI 0.9 to 1.5) for overweight men and 1.7 ( 95% CI 1.0 to 2.9) for obese men. The OR for having a TKR was 1.7 ( 95% CI 1.1 to 2.6) for overweight men and 5.3 ( 95% CI 2.8 to 10.1) for obese men. The OR for having a THR was 1.0 ( 95% CI 0.8 to 1.3) for overweight women and 1.0 ( 95% CI 0.6 to 1.5) for obese women. The OR for having a TKR was 1.6 ( 95% CI 1.1 to 2.2) for overweight women and 4.0 ( 95% CI 2.6 to 6.1) for obese women. Conclusion: This study supports a positive association between high BMI and TKR in both sexes, but for THR the association with BMI seems to be weaker, and possibly negligible for women. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1405118
- author
- Franklin, Jonas
LU
; Ingvarsson, T.
; Englund, Martin
LU
and Lohmander, Stefan
LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Annals of the Rheumatic Diseases
- volume
- 68
- issue
- 4
- pages
- 536 - 540
- publisher
- BMJ Publishing Group
- external identifiers
-
- wos:000264196000015
- scopus:65249189311
- ISSN
- 1468-2060
- DOI
- 10.1136/ard.2007.086868
- language
- English
- LU publication?
- yes
- id
- e76d6ec8-cb0a-4f0e-9ab3-cb4fc0dfc20b (old id 1405118)
- date added to LUP
- 2016-04-01 15:00:04
- date last changed
- 2023-01-04 07:55:48
@article{e76d6ec8-cb0a-4f0e-9ab3-cb4fc0dfc20b,
abstract = {{Objective: To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement. Methods: Case-control study design. All patients still living in Iceland who had had a THR or TKR resulting from OA before the end of 2002 were invited to participate. First-degree relatives of participating patients served as controls. A total of 1473 patients ( 872 women) and 1103 controls ( 599 women), all born between 1910 and 1939 and who had answered a questionnaire including questions about height and weight, were analysed. A randomly selected sample, representative of the Icelandic population, was used as a secondary control group. Results: The OR, adjusted for age, occupation and presence of hand OA, for having a THR was 1.1 (95% CI 0.9 to 1.5) for overweight men and 1.7 ( 95% CI 1.0 to 2.9) for obese men. The OR for having a TKR was 1.7 ( 95% CI 1.1 to 2.6) for overweight men and 5.3 ( 95% CI 2.8 to 10.1) for obese men. The OR for having a THR was 1.0 ( 95% CI 0.8 to 1.3) for overweight women and 1.0 ( 95% CI 0.6 to 1.5) for obese women. The OR for having a TKR was 1.6 ( 95% CI 1.1 to 2.2) for overweight women and 4.0 ( 95% CI 2.6 to 6.1) for obese women. Conclusion: This study supports a positive association between high BMI and TKR in both sexes, but for THR the association with BMI seems to be weaker, and possibly negligible for women.}},
author = {{Franklin, Jonas and Ingvarsson, T. and Englund, Martin and Lohmander, Stefan}},
issn = {{1468-2060}},
language = {{eng}},
number = {{4}},
pages = {{536--540}},
publisher = {{BMJ Publishing Group}},
series = {{Annals of the Rheumatic Diseases}},
title = {{Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis}},
url = {{http://dx.doi.org/10.1136/ard.2007.086868}},
doi = {{10.1136/ard.2007.086868}},
volume = {{68}},
year = {{2009}},
}