Prevalence of sexually transmitted infections (HIV, hepatitis B virus, herpes simplex virus type 2, and syphilis) in pregnant women in Ethiopia : Trends over 10 years (2005-2014)
(2019) In International Journal of Infectious Diseases 79. p.50-57- Abstract
OBJECTIVES: This study was performed to determine the trends in seroprevalence of four major sexually transmitted infections (STIs) (HIV, hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), and syphilis) over a 10-year period (2005-2014) in pregnant women in Ethiopia.
METHODS: Pregnant women (15-49 years old) who were enrolled in the antenatal care-based national HIV surveillance were included. Serological tests for HIV, HBV, HSV-2, and syphilis were done on serum/plasma samples.
RESULTS: A total of 4887 pregnant women were included. Results showed a decline in prevalence of these STIs by 40-60% over the 10 years (2005-2014): HIV (10.5% to 5.5%), syphilis (2.5% to 1.1%), HBV (12.6% to 6.7%), and HSV-2 (47.5% to... (More)
OBJECTIVES: This study was performed to determine the trends in seroprevalence of four major sexually transmitted infections (STIs) (HIV, hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), and syphilis) over a 10-year period (2005-2014) in pregnant women in Ethiopia.
METHODS: Pregnant women (15-49 years old) who were enrolled in the antenatal care-based national HIV surveillance were included. Serological tests for HIV, HBV, HSV-2, and syphilis were done on serum/plasma samples.
RESULTS: A total of 4887 pregnant women were included. Results showed a decline in prevalence of these STIs by 40-60% over the 10 years (2005-2014): HIV (10.5% to 5.5%), syphilis (2.5% to 1.1%), HBV (12.6% to 6.7%), and HSV-2 (47.5% to 28.5%). In 2014, 109/4887 (2.2%) women had triple infections. In 2005, 2007, and 2009, the prevalence of HSV-2 in the older age group (35-45 years) (47.1%, 47.4%, and 50.0%, respectively) was higher than that in the younger age group (15-24 years) (40.9%, 19.5%, and 20.2%, respectively). Age category (Chi-square=22.4, p<0.001), study sites/residence (Chi-square=135.2, p=0.001), and time/years (Chi-square=58.9, p=0.001) were associated with a positive HSV-2 test result.
CONCLUSIONS: A decline in HIV, HBV, HSV-2, and syphilis of >40% was seen over the years in Ethiopia. However, an intermediate endemicity level of HBV and higher prevalence of HIV and HSV-2 by 2014, suggest the need to strengthen prevention strategy for STIs.
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- author
- Kassa, Desta ; Gebremichael, Gebremedhin ; Tilahun, Tesfaye ; Ayalkebet, Abenezer ; Abrha, Yemane ; Mesfin, Getnet ; Belay, Yohannes ; Demissie, Minilik LU ; Gebrexiabher, Atsbeha and Assefa, Yibeltal
- publishing date
- 2019-02
- type
- Contribution to journal
- publication status
- published
- keywords
- Adolescent, Adult, Ethiopia/epidemiology, Female, HIV Infections/epidemiology, Hepatitis B/epidemiology, Herpes Genitalis/epidemiology, Herpesvirus 2, Human, Humans, Middle Aged, Pregnancy, Pregnancy Complications, Infectious/epidemiology, Prevalence, Seroepidemiologic Studies, Sexually Transmitted Diseases, Viral/epidemiology, Syphilis/epidemiology, Young Adult
- in
- International Journal of Infectious Diseases
- volume
- 79
- pages
- 50 - 57
- publisher
- Elsevier
- external identifiers
-
- pmid:30472433
- scopus:85058210180
- ISSN
- 1878-3511
- DOI
- 10.1016/j.ijid.2018.11.009
- language
- English
- LU publication?
- no
- id
- e7eea196-1b57-4ae9-86ed-271c1c78cad8
- date added to LUP
- 2019-09-12 09:54:30
- date last changed
- 2024-01-01 18:54:12
@article{e7eea196-1b57-4ae9-86ed-271c1c78cad8, abstract = {{<p>OBJECTIVES: This study was performed to determine the trends in seroprevalence of four major sexually transmitted infections (STIs) (HIV, hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), and syphilis) over a 10-year period (2005-2014) in pregnant women in Ethiopia.</p><p>METHODS: Pregnant women (15-49 years old) who were enrolled in the antenatal care-based national HIV surveillance were included. Serological tests for HIV, HBV, HSV-2, and syphilis were done on serum/plasma samples.</p><p>RESULTS: A total of 4887 pregnant women were included. Results showed a decline in prevalence of these STIs by 40-60% over the 10 years (2005-2014): HIV (10.5% to 5.5%), syphilis (2.5% to 1.1%), HBV (12.6% to 6.7%), and HSV-2 (47.5% to 28.5%). In 2014, 109/4887 (2.2%) women had triple infections. In 2005, 2007, and 2009, the prevalence of HSV-2 in the older age group (35-45 years) (47.1%, 47.4%, and 50.0%, respectively) was higher than that in the younger age group (15-24 years) (40.9%, 19.5%, and 20.2%, respectively). Age category (Chi-square=22.4, p<0.001), study sites/residence (Chi-square=135.2, p=0.001), and time/years (Chi-square=58.9, p=0.001) were associated with a positive HSV-2 test result.</p><p>CONCLUSIONS: A decline in HIV, HBV, HSV-2, and syphilis of >40% was seen over the years in Ethiopia. However, an intermediate endemicity level of HBV and higher prevalence of HIV and HSV-2 by 2014, suggest the need to strengthen prevention strategy for STIs.</p>}}, author = {{Kassa, Desta and Gebremichael, Gebremedhin and Tilahun, Tesfaye and Ayalkebet, Abenezer and Abrha, Yemane and Mesfin, Getnet and Belay, Yohannes and Demissie, Minilik and Gebrexiabher, Atsbeha and Assefa, Yibeltal}}, issn = {{1878-3511}}, keywords = {{Adolescent; Adult; Ethiopia/epidemiology; Female; HIV Infections/epidemiology; Hepatitis B/epidemiology; Herpes Genitalis/epidemiology; Herpesvirus 2, Human; Humans; Middle Aged; Pregnancy; Pregnancy Complications, Infectious/epidemiology; Prevalence; Seroepidemiologic Studies; Sexually Transmitted Diseases, Viral/epidemiology; Syphilis/epidemiology; Young Adult}}, language = {{eng}}, pages = {{50--57}}, publisher = {{Elsevier}}, series = {{International Journal of Infectious Diseases}}, title = {{Prevalence of sexually transmitted infections (HIV, hepatitis B virus, herpes simplex virus type 2, and syphilis) in pregnant women in Ethiopia : Trends over 10 years (2005-2014)}}, url = {{http://dx.doi.org/10.1016/j.ijid.2018.11.009}}, doi = {{10.1016/j.ijid.2018.11.009}}, volume = {{79}}, year = {{2019}}, }