Gelatin cryogels crosslinked with oxidized dextran and containing freshly formed hydroxyapatite as potential bone tissue-engineering scaffolds
(2013) In Journal of Tissue Engineering and Regenerative Medicine 7(7). p.584-588- Abstract
- Gelatin-based cryogels were prepared by using a novel crosslinker, oxidized dextran, which was synthesized and used in the study. The cryogels were also loaded with freshly formed hydroxyapatite (HA) particles. These cryogels are opaque, spongy and highly elastic and have a pore structure with large interconnected pores. They swell about 500% in aqueous media and within a few minutes reach their final swollen forms. The elastic moduli of HA-containing cryogels were 18.5 +/- 3.0 kPa, which is suitable for non-load-bearing bone tissue-engineering (TE) applications, especially for the craniofacial area. Copyright (c) 2012 John Wiley & Sons, Ltd.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3987267
- author
- Inci, Ilyas ; Kirsebom, Harald LU ; Galaev, Igor LU ; Mattiasson, Bo LU and Piskin, Erhan
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- cryogelation, cryogel, scaffold, bone tissue engineering, gelatin, hydroxyapatite, oxidized dextran as crosslinker
- in
- Journal of Tissue Engineering and Regenerative Medicine
- volume
- 7
- issue
- 7
- pages
- 584 - 588
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000320728400008
- scopus:84879550478
- pmid:22733656
- ISSN
- 1932-6254
- DOI
- 10.1002/term.1464
- language
- English
- LU publication?
- yes
- id
- e831bbce-79ef-4608-9b99-08279f7bccc5 (old id 3987267)
- date added to LUP
- 2016-04-01 09:56:35
- date last changed
- 2022-02-24 20:47:01
@article{e831bbce-79ef-4608-9b99-08279f7bccc5, abstract = {{Gelatin-based cryogels were prepared by using a novel crosslinker, oxidized dextran, which was synthesized and used in the study. The cryogels were also loaded with freshly formed hydroxyapatite (HA) particles. These cryogels are opaque, spongy and highly elastic and have a pore structure with large interconnected pores. They swell about 500% in aqueous media and within a few minutes reach their final swollen forms. The elastic moduli of HA-containing cryogels were 18.5 +/- 3.0 kPa, which is suitable for non-load-bearing bone tissue-engineering (TE) applications, especially for the craniofacial area. Copyright (c) 2012 John Wiley & Sons, Ltd.}}, author = {{Inci, Ilyas and Kirsebom, Harald and Galaev, Igor and Mattiasson, Bo and Piskin, Erhan}}, issn = {{1932-6254}}, keywords = {{cryogelation; cryogel; scaffold; bone tissue engineering; gelatin; hydroxyapatite; oxidized dextran as crosslinker}}, language = {{eng}}, number = {{7}}, pages = {{584--588}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Journal of Tissue Engineering and Regenerative Medicine}}, title = {{Gelatin cryogels crosslinked with oxidized dextran and containing freshly formed hydroxyapatite as potential bone tissue-engineering scaffolds}}, url = {{http://dx.doi.org/10.1002/term.1464}}, doi = {{10.1002/term.1464}}, volume = {{7}}, year = {{2013}}, }