Biofuel cell based on microscale nanostructured electrodes with inductive coupling to rat brain neurons.
(2013) In Scientific Reports 3(Nov 20).- Abstract
- Miniature, self-contained biodevices powered by biofuel cells may enable a new generation of implantable, wireless, minimally invasive neural interfaces for neurophysiological in vivo studies and for clinical applications. Here we report on the fabrication of a direct electron transfer based glucose/oxygen enzymatic fuel cell (EFC) from genuinely three-dimensional (3D) nanostructured microscale gold electrodes, modified with suitable biocatalysts. We show that the process underlying the simple fabrication method of 3D nanostructured electrodes is based on an electrochemically driven transformation of physically deposited gold nanoparticles. We experimentally demonstrate that mediator-, cofactor-, and membrane-less EFCs do operate in... (More)
- Miniature, self-contained biodevices powered by biofuel cells may enable a new generation of implantable, wireless, minimally invasive neural interfaces for neurophysiological in vivo studies and for clinical applications. Here we report on the fabrication of a direct electron transfer based glucose/oxygen enzymatic fuel cell (EFC) from genuinely three-dimensional (3D) nanostructured microscale gold electrodes, modified with suitable biocatalysts. We show that the process underlying the simple fabrication method of 3D nanostructured electrodes is based on an electrochemically driven transformation of physically deposited gold nanoparticles. We experimentally demonstrate that mediator-, cofactor-, and membrane-less EFCs do operate in cerebrospinal fluid and in the brain of a rat, producing amounts of electrical power sufficient to drive a self-contained biodevice, viz. 7 μW cm(-2) in vitro and 2 μW cm(-2) in vivo at an operating voltage of 0.4 V. Last but not least, we also demonstrate an inductive coupling between 3D nanobioelectrodes and living neurons. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4179157
- author
- Andoralov, Viktor ; Falk, Magnus ; Suyatin, Dmitry LU ; Granmo, Marcus LU ; Sotres, Javier ; Ludwig, Roland ; Popov, Vladimir O ; Schouenborg, Jens LU ; Blum, Zoltan and Shleev, Sergey
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scientific Reports
- volume
- 3
- issue
- Nov 20
- article number
- 3270
- publisher
- Nature Publishing Group
- external identifiers
-
- wos:000327517300007
- pmid:24253492
- scopus:84888250095
- pmid:24253492
- ISSN
- 2045-2322
- DOI
- 10.1038/srep03270
- language
- English
- LU publication?
- yes
- id
- e8d6c13b-1549-4f3c-8c04-d03e7ef17574 (old id 4179157)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24253492?dopt=Abstract
- date added to LUP
- 2016-04-01 13:15:56
- date last changed
- 2024-06-05 09:58:21
@article{e8d6c13b-1549-4f3c-8c04-d03e7ef17574, abstract = {{Miniature, self-contained biodevices powered by biofuel cells may enable a new generation of implantable, wireless, minimally invasive neural interfaces for neurophysiological in vivo studies and for clinical applications. Here we report on the fabrication of a direct electron transfer based glucose/oxygen enzymatic fuel cell (EFC) from genuinely three-dimensional (3D) nanostructured microscale gold electrodes, modified with suitable biocatalysts. We show that the process underlying the simple fabrication method of 3D nanostructured electrodes is based on an electrochemically driven transformation of physically deposited gold nanoparticles. We experimentally demonstrate that mediator-, cofactor-, and membrane-less EFCs do operate in cerebrospinal fluid and in the brain of a rat, producing amounts of electrical power sufficient to drive a self-contained biodevice, viz. 7 μW cm(-2) in vitro and 2 μW cm(-2) in vivo at an operating voltage of 0.4 V. Last but not least, we also demonstrate an inductive coupling between 3D nanobioelectrodes and living neurons.}}, author = {{Andoralov, Viktor and Falk, Magnus and Suyatin, Dmitry and Granmo, Marcus and Sotres, Javier and Ludwig, Roland and Popov, Vladimir O and Schouenborg, Jens and Blum, Zoltan and Shleev, Sergey}}, issn = {{2045-2322}}, language = {{eng}}, number = {{Nov 20}}, publisher = {{Nature Publishing Group}}, series = {{Scientific Reports}}, title = {{Biofuel cell based on microscale nanostructured electrodes with inductive coupling to rat brain neurons.}}, url = {{https://lup.lub.lu.se/search/files/3267361/4391832.pdf}}, doi = {{10.1038/srep03270}}, volume = {{3}}, year = {{2013}}, }