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Implementation of clinical practices and pathways optimizing ACS patients lipid management : Focus on eight European initiatives

Alings, Marco ; Descamps, Olivier ; Guillon, Benoit ; Leosdottir, Margret LU ; Maggioni, Aldo P. ; Recasens, Lluis ; Speidl, Walter S. ; Tripodi, Rosario V. ; Landmesser, Ulf and Catapano, Alberico L. , et al. (2020) In Atherosclerosis Supplements 42. p.59-64
Abstract

Post-acute coronary syndrome (ACS) patients are at very high cardiovascular risk. Despite current guidelines strongly recommend to reduce LDL-C levels and initiation of high-intensity statins as early as possible in patients admitted with an ACS, less than half of ACS patients receive a high intensity statin, and a high percentage of has LDL-C well above the goal despite therapy. There are multiple reasons for that, including physician lack of guideline adherence, patient lack of compliance with treatment, and lack of standardized procedures. Furthermore, although the prevalence of familial hypercholesterolemia is higher among patients with ACS, this condition remains poorly estimated. To fill these gaps, some European countries have... (More)

Post-acute coronary syndrome (ACS) patients are at very high cardiovascular risk. Despite current guidelines strongly recommend to reduce LDL-C levels and initiation of high-intensity statins as early as possible in patients admitted with an ACS, less than half of ACS patients receive a high intensity statin, and a high percentage of has LDL-C well above the goal despite therapy. There are multiple reasons for that, including physician lack of guideline adherence, patient lack of compliance with treatment, and lack of standardized procedures. Furthermore, although the prevalence of familial hypercholesterolemia is higher among patients with ACS, this condition remains poorly estimated. To fill these gaps, some European countries have launched local initiatives for the in-hospital and post-discharge ACS patient lipid management. It appears that ensuring optimal therapy during hospitalization and dedicated follow-up protocols results in a significant improvement of lipid levels in these very high risk patients, which may translate into a reduced risk of recurrent future events.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
Acute coronary syndrome, Guidelines, Lipid management, Low-density lipoprotein cholesterol
in
Atherosclerosis Supplements
volume
42
pages
59 - 64
publisher
Elsevier
external identifiers
  • scopus:85100668534
  • pmid:33589225
ISSN
1567-5688
DOI
10.1016/j.atherosclerosissup.2021.01.010
language
English
LU publication?
no
id
e9abdc4c-c3b0-43f3-b596-47d0744df2bf
date added to LUP
2021-02-26 12:19:49
date last changed
2024-05-02 04:25:04
@article{e9abdc4c-c3b0-43f3-b596-47d0744df2bf,
  abstract     = {{<p>Post-acute coronary syndrome (ACS) patients are at very high cardiovascular risk. Despite current guidelines strongly recommend to reduce LDL-C levels and initiation of high-intensity statins as early as possible in patients admitted with an ACS, less than half of ACS patients receive a high intensity statin, and a high percentage of has LDL-C well above the goal despite therapy. There are multiple reasons for that, including physician lack of guideline adherence, patient lack of compliance with treatment, and lack of standardized procedures. Furthermore, although the prevalence of familial hypercholesterolemia is higher among patients with ACS, this condition remains poorly estimated. To fill these gaps, some European countries have launched local initiatives for the in-hospital and post-discharge ACS patient lipid management. It appears that ensuring optimal therapy during hospitalization and dedicated follow-up protocols results in a significant improvement of lipid levels in these very high risk patients, which may translate into a reduced risk of recurrent future events.</p>}},
  author       = {{Alings, Marco and Descamps, Olivier and Guillon, Benoit and Leosdottir, Margret and Maggioni, Aldo P. and Recasens, Lluis and Speidl, Walter S. and Tripodi, Rosario V. and Landmesser, Ulf and Catapano, Alberico L. and Pirillo, Angela}},
  issn         = {{1567-5688}},
  keywords     = {{Acute coronary syndrome; Guidelines; Lipid management; Low-density lipoprotein cholesterol}},
  language     = {{eng}},
  pages        = {{59--64}},
  publisher    = {{Elsevier}},
  series       = {{Atherosclerosis Supplements}},
  title        = {{Implementation of clinical practices and pathways optimizing ACS patients lipid management : Focus on eight European initiatives}},
  url          = {{http://dx.doi.org/10.1016/j.atherosclerosissup.2021.01.010}},
  doi          = {{10.1016/j.atherosclerosissup.2021.01.010}},
  volume       = {{42}},
  year         = {{2020}},
}