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Depressivity and mortality risk in a cohort of elderly men. A role of cognitive and vascular ill-health, and social participation

Jönsson, Max and Siennicki-Lantz, Arkadiusz LU (2019) In Aging and Mental Health
Abstract

Objectives: Depressive symptoms in the elderly have been shown to be associated with increased mortality. The purpose of this study was to examine symptoms of depression in octogenarian men and their association with all-cause mortality, and whether physical, cognitive and social factors influence this association. Methods: Out of the 703 initially included 55-years-old men, from the prospective cohort study “Men born in 1914”, we studied 163 survivors who could take a part in a survey at age 81, and followed them until their death. Results: Those men who had at least mild depressive symptoms, defined with Zung Self-rating Depression Scale, were found to have an increased mortality risk (HR = 1.52; CI =1.10–2.08; p = 0.01). This... (More)

Objectives: Depressive symptoms in the elderly have been shown to be associated with increased mortality. The purpose of this study was to examine symptoms of depression in octogenarian men and their association with all-cause mortality, and whether physical, cognitive and social factors influence this association. Methods: Out of the 703 initially included 55-years-old men, from the prospective cohort study “Men born in 1914”, we studied 163 survivors who could take a part in a survey at age 81, and followed them until their death. Results: Those men who had at least mild depressive symptoms, defined with Zung Self-rating Depression Scale, were found to have an increased mortality risk (HR = 1.52; CI =1.10–2.08; p = 0.01). This association persisted significantly after adjusting for: education, global cognition at age 81, cognitive abilities at age 68, vascular risk factors and comorbidities. Instead, it was attenuated after adjustments for Activities of Daily Life (ADL)–dependency and for a grade of Satisfaction with Participation in daily life. Conclusion: In octogenarian men with survival above the average, mild depressive symptoms predict all-cause mortality. Neither cognitive capacity nor vascular comorbidity explained this association, but lower Satisfaction with Participation in daily life, especially in combination with moderate ADL-dependency.

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author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
activities of daily living, Aged, depression, male, personal satisfaction, risk factors
in
Aging and Mental Health
publisher
Carfax Publishing
external identifiers
  • scopus:85063902736
ISSN
1360-7863
DOI
10.1080/13607863.2019.1597012
language
English
LU publication?
yes
id
ea23758c-ea1e-4aff-ab5e-a9a5752be5ab
date added to LUP
2019-04-23 08:25:53
date last changed
2019-05-14 04:53:41
@article{ea23758c-ea1e-4aff-ab5e-a9a5752be5ab,
  abstract     = {<p>Objectives: Depressive symptoms in the elderly have been shown to be associated with increased mortality. The purpose of this study was to examine symptoms of depression in octogenarian men and their association with all-cause mortality, and whether physical, cognitive and social factors influence this association. Methods: Out of the 703 initially included 55-years-old men, from the prospective cohort study “Men born in 1914”, we studied 163 survivors who could take a part in a survey at age 81, and followed them until their death. Results: Those men who had at least mild depressive symptoms, defined with Zung Self-rating Depression Scale, were found to have an increased mortality risk (HR = 1.52; CI =1.10–2.08; p = 0.01). This association persisted significantly after adjusting for: education, global cognition at age 81, cognitive abilities at age 68, vascular risk factors and comorbidities. Instead, it was attenuated after adjustments for Activities of Daily Life (ADL)–dependency and for a grade of Satisfaction with Participation in daily life. Conclusion: In octogenarian men with survival above the average, mild depressive symptoms predict all-cause mortality. Neither cognitive capacity nor vascular comorbidity explained this association, but lower Satisfaction with Participation in daily life, especially in combination with moderate ADL-dependency.</p>},
  author       = {Jönsson, Max and Siennicki-Lantz, Arkadiusz},
  issn         = {1360-7863},
  keyword      = {activities of daily living,Aged,depression,male,personal satisfaction,risk factors},
  language     = {eng},
  month        = {04},
  publisher    = {Carfax Publishing},
  series       = {Aging and Mental Health},
  title        = {Depressivity and mortality risk in a cohort of elderly men. A role of cognitive and vascular ill-health, and social participation},
  url          = {http://dx.doi.org/10.1080/13607863.2019.1597012},
  year         = {2019},
}