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Animal models of immune thrombocytopenia (ITP)

Semple, John W LU (2010) In Annals of Hematology 89 (Suppl 1). p.37-44
Abstract

With regards to research animal models related to immune thrombocytopenia (ITP), there is an extensive literature of over 300 publications published since 1959. It appears that many of these models either confirm what has been found in human ITP or, in some instances, are the first to describe a phenomenon related to ITP that is still of relevance today in human medicine. These models will undoubtedly play a significant role in the future research of human ITP particularly related to understanding of the pathogenesis of the disorder and the development of novel therapeutics. This review will highlight some of the major animal models utilized for ITP research and will present a somewhat historical aspect of the subject.

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author
publishing date
type
Contribution to journal
publication status
published
keywords
Animals, Animals, Laboratory, Blood Platelets, Chronic Disease, Disease Models, Animal, Drug-Related Side Effects and Adverse Reactions, Humans, Infection, Purpura, Thrombocytopenic, Idiopathic, Journal Article, Review
in
Annals of Hematology
volume
89
issue
Suppl 1
pages
8 pages
publisher
Springer
external identifiers
  • Scopus:77955657769
ISSN
1432-0584
DOI
10.1007/s00277-009-0882-8
language
English
LU publication?
no
id
ea72d935-f4f5-4a62-9af8-4d0e1fe427ee
date added to LUP
2016-09-23 12:06:19
date last changed
2017-01-01 08:35:03
@article{ea72d935-f4f5-4a62-9af8-4d0e1fe427ee,
  abstract     = {<p>With regards to research animal models related to immune thrombocytopenia (ITP), there is an extensive literature of over 300 publications published since 1959. It appears that many of these models either confirm what has been found in human ITP or, in some instances, are the first to describe a phenomenon related to ITP that is still of relevance today in human medicine. These models will undoubtedly play a significant role in the future research of human ITP particularly related to understanding of the pathogenesis of the disorder and the development of novel therapeutics. This review will highlight some of the major animal models utilized for ITP research and will present a somewhat historical aspect of the subject.</p>},
  author       = {Semple, John W},
  issn         = {1432-0584},
  keyword      = {Animals,Animals, Laboratory,Blood Platelets,Chronic Disease,Disease Models, Animal,Drug-Related Side Effects and Adverse Reactions,Humans,Infection,Purpura, Thrombocytopenic, Idiopathic,Journal Article,Review},
  language     = {eng},
  number       = {Suppl 1},
  pages        = {37--44},
  publisher    = {Springer},
  series       = {Annals of Hematology},
  title        = {Animal models of immune thrombocytopenia (ITP)},
  url          = {http://dx.doi.org/10.1007/s00277-009-0882-8},
  volume       = {89 },
  year         = {2010},
}