Nano-scale Infrared Imaging of β-sheet Structures in Synaptic Junctions of Primary Neurons Isolated from Transgenic Mice
Klementieva, O. LU
; Mathurin, J.
; Engdahl, A.
LU
; Freitas, R.
; Willen, K.
LU
; Uvdal, P.
LU
; Miller, L. M.
and Gouras, G.
LU
(2018)
43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018
2018-September.
- Abstract
Aβ is a class of aggregation-prone proteins, which may misfold into stable, β-sheet rich fibrils. Aβ is linked to the development of synaptic pathology in Alzheimer's disease (AD). However, a main question in the AD field is how Aβ contributes to AD neuropathology? Up to now there is little evidence for protein structural changes in diseased neuron. Our aim is to study the distribution of β-sheet structures in AD transgenic neurons in order to uncover sub-cellular mechanism(s) by which amyloid β-sheet structures are involved in AD pathology.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/ea7ecf85-7628-4f44-96ce-81a765c24107
- author
- Klementieva, O.
LU
; Mathurin, J.
; Engdahl, A.
LU
; Freitas, R.
; Willen, K.
LU
; Uvdal, P.
LU
; Miller, L. M.
and Gouras, G.
LU
- organization
- publishing date
- 2018-10-29
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- 2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018
- volume
- 2018-September
- article number
- 8510376
- publisher
- IEEE Computer Society
- conference name
- 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018
- conference location
- Nagoya, Japan
- conference dates
- 2018-09-09 - 2018-09-14
- external identifiers
-
- scopus:85056832774
- ISBN
- 9781538638095
- DOI
- 10.1109/IRMMW-THz.2018.8510376
- language
- English
- LU publication?
- yes
- id
- ea7ecf85-7628-4f44-96ce-81a765c24107
- date added to LUP
- 2018-11-29 14:19:41
- date last changed
- 2022-05-03 08:24:51
@inproceedings{ea7ecf85-7628-4f44-96ce-81a765c24107,
abstract = {{<p>Aβ is a class of aggregation-prone proteins, which may misfold into stable, β-sheet rich fibrils. Aβ is linked to the development of synaptic pathology in Alzheimer's disease (AD). However, a main question in the AD field is how Aβ contributes to AD neuropathology? Up to now there is little evidence for protein structural changes in diseased neuron. Our aim is to study the distribution of β-sheet structures in AD transgenic neurons in order to uncover sub-cellular mechanism(s) by which amyloid β-sheet structures are involved in AD pathology.</p>}},
author = {{Klementieva, O. and Mathurin, J. and Engdahl, A. and Freitas, R. and Willen, K. and Uvdal, P. and Miller, L. M. and Gouras, G.}},
booktitle = {{2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018}},
isbn = {{9781538638095}},
language = {{eng}},
month = {{10}},
publisher = {{IEEE Computer Society}},
title = {{Nano-scale Infrared Imaging of β-sheet Structures in Synaptic Junctions of Primary Neurons Isolated from Transgenic Mice}},
url = {{http://dx.doi.org/10.1109/IRMMW-THz.2018.8510376}},
doi = {{10.1109/IRMMW-THz.2018.8510376}},
volume = {{2018-September}},
year = {{2018}},
}