Reduced voluntary non-visual suppression of the vestibulo-ocular reflex gain during nitrous oxide narcosis
Padoan, S ; Magnusson, M LU
; Akesson, M
and Ornhagen, H
(1992)
In Aviation Space and Environmental Medicine
63(10).
p.80-875
- Abstract
The effect of subanesthetic nitrous oxide (N2O) narcosis (21%) on the vestibulo-ocular reflex (VOR) and on voluntary non-visual suppression of the VOR was studied in 12 subjects, using a velocity step rotational test. Gain and time constant of the VOR were calculated by computer. During tests, the subjects were required either to perform mental arithmetic or to attempt to follow an imaginary target rotating with them in the dark. Voluntary non-visual suppression of gain was significantly reduced during exposure to N2O, though there was no statistically significant effect of N2O on gain per se. The time constant was unaffected either by voluntary suppression or by N2O. The reducing effect of N2O on voluntary non-visual suppression of VOR... (More)
The effect of subanesthetic nitrous oxide (N2O) narcosis (21%) on the vestibulo-ocular reflex (VOR) and on voluntary non-visual suppression of the VOR was studied in 12 subjects, using a velocity step rotational test. Gain and time constant of the VOR were calculated by computer. During tests, the subjects were required either to perform mental arithmetic or to attempt to follow an imaginary target rotating with them in the dark. Voluntary non-visual suppression of gain was significantly reduced during exposure to N2O, though there was no statistically significant effect of N2O on gain per se. The time constant was unaffected either by voluntary suppression or by N2O. The reducing effect of N2O on voluntary non-visual suppression of VOR gain is assumed to be due to reduced alertness. Reduced voluntary non-visual suppression of VOR may imply reduced visual-vestibular interaction, which might be one explanation of the complaints of dizziness associated with fatigue or with ingestion of certain sedatives.
(Less)
- author
- Padoan, S
; Magnusson, M
LU
; Akesson, M
and Ornhagen, H
- organization
- publishing date
- 1992-10
- type
- Contribution to journal
- publication status
- published
- keywords
- Adult, Female, Humans, Inert Gas Narcosis, Male, Nitrous Oxide, Reflex, Vestibulo-Ocular, Vision, Ocular, Journal Article, Research Support, Non-U.S. Gov't
- in
- Aviation Space and Environmental Medicine
- volume
- 63
- issue
- 10
- pages
- 6 pages
- publisher
- Aerospace Medical Association
- external identifiers
-
- scopus:0026730176
- pmid:1417649
- ISSN
- 0095-6562
- language
- English
- LU publication?
- yes
- id
- ea893f39-71da-474c-9917-347f9df22c97
- date added to LUP
- 2017-05-03 12:35:01
- date last changed
- 2024-01-13 19:53:02
@article{ea893f39-71da-474c-9917-347f9df22c97,
abstract = {{<p>The effect of subanesthetic nitrous oxide (N2O) narcosis (21%) on the vestibulo-ocular reflex (VOR) and on voluntary non-visual suppression of the VOR was studied in 12 subjects, using a velocity step rotational test. Gain and time constant of the VOR were calculated by computer. During tests, the subjects were required either to perform mental arithmetic or to attempt to follow an imaginary target rotating with them in the dark. Voluntary non-visual suppression of gain was significantly reduced during exposure to N2O, though there was no statistically significant effect of N2O on gain per se. The time constant was unaffected either by voluntary suppression or by N2O. The reducing effect of N2O on voluntary non-visual suppression of VOR gain is assumed to be due to reduced alertness. Reduced voluntary non-visual suppression of VOR may imply reduced visual-vestibular interaction, which might be one explanation of the complaints of dizziness associated with fatigue or with ingestion of certain sedatives.</p>}},
author = {{Padoan, S and Magnusson, M and Akesson, M and Ornhagen, H}},
issn = {{0095-6562}},
keywords = {{Adult; Female; Humans; Inert Gas Narcosis; Male; Nitrous Oxide; Reflex, Vestibulo-Ocular; Vision, Ocular; Journal Article; Research Support, Non-U.S. Gov't}},
language = {{eng}},
number = {{10}},
pages = {{80--875}},
publisher = {{Aerospace Medical Association}},
series = {{Aviation Space and Environmental Medicine}},
title = {{Reduced voluntary non-visual suppression of the vestibulo-ocular reflex gain during nitrous oxide narcosis}},
volume = {{63}},
year = {{1992}},
}