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Decreased responsiveness to immune complexes of granulocytes from patients with acute leukemia in remission demonstrated by microcalorimetry

Ankerst, J. LU orcid ; Fäldt, R. LU and Monti, M. (1984) In Leukemia Research 8(6). p.997-1002
Abstract

Functional activity of granulocytes from healthy individuals and from patients with acute leukemia in remission was studied. The increase of heat production rate (metabolic activity) after stimulation of the blood cells with in vitro formed immune complexes was measured by microcalorimeters of heat conduction type. It was demonstrated that increased heat production rate after exposure to immune complexes was significantly lower (p<0.0005) in 9 patients with acute leukemia with a remission duration of less than 6 months than in 25 healthy volunteers.

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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Acute leukemia, granulocytes in remission, heat production rate, immune complexes, microcalorimetry
in
Leukemia Research
volume
8
issue
6
pages
997 - 1002
publisher
Elsevier
external identifiers
  • scopus:0021690569
  • pmid:6513581
ISSN
0145-2126
DOI
10.1016/0145-2126(84)90053-5
language
English
LU publication?
yes
id
eb1ceaad-ff23-4bdf-b139-969ab5e0d33d
date added to LUP
2021-01-21 14:29:24
date last changed
2024-01-03 05:35:45
@article{eb1ceaad-ff23-4bdf-b139-969ab5e0d33d,
  abstract     = {{<p>Functional activity of granulocytes from healthy individuals and from patients with acute leukemia in remission was studied. The increase of heat production rate (metabolic activity) after stimulation of the blood cells with in vitro formed immune complexes was measured by microcalorimeters of heat conduction type. It was demonstrated that increased heat production rate after exposure to immune complexes was significantly lower (p&lt;0.0005) in 9 patients with acute leukemia with a remission duration of less than 6 months than in 25 healthy volunteers.</p>}},
  author       = {{Ankerst, J. and Fäldt, R. and Monti, M.}},
  issn         = {{0145-2126}},
  keywords     = {{Acute leukemia; granulocytes in remission; heat production rate; immune complexes; microcalorimetry}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{997--1002}},
  publisher    = {{Elsevier}},
  series       = {{Leukemia Research}},
  title        = {{Decreased responsiveness to immune complexes of granulocytes from patients with acute leukemia in remission demonstrated by microcalorimetry}},
  url          = {{http://dx.doi.org/10.1016/0145-2126(84)90053-5}},
  doi          = {{10.1016/0145-2126(84)90053-5}},
  volume       = {{8}},
  year         = {{1984}},
}