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Quantitative X-ray phase-contrast computed tomography at 82 keV

Willner, Marian; Bech, Martin LU ; Herzen, Julia; Zanette, Irene; Hahn, Dieter; Kenntner, Johannes; Mohr, Juergen; Rack, Alexander; Weitkamp, Timm and Pfeiffer, Franz (2013) In Optics Express 21(4). p.4155-4166
Abstract
Potential applications of grating-based X-ray phase-contrast imaging are investigated in various fields due to its compatibility with laboratory X-ray sources. So far the method was mainly restricted to X-ray energies below 40 keV, which is too low to examine dense or thick objects, but a routine operation at higher energies is on the brink of realisation. In this study, imaging results obtained at 82 keV are presented. These comprise a test object consisting of well-defined materials for a quantitative analysis and a tooth to translate the findings to a biomedical sample. Measured linear attenuation coefficients mu and electron densities rho(e) are in good agreement with theoretical values. Improved contrast-to-noise ratios were found in... (More)
Potential applications of grating-based X-ray phase-contrast imaging are investigated in various fields due to its compatibility with laboratory X-ray sources. So far the method was mainly restricted to X-ray energies below 40 keV, which is too low to examine dense or thick objects, but a routine operation at higher energies is on the brink of realisation. In this study, imaging results obtained at 82 keV are presented. These comprise a test object consisting of well-defined materials for a quantitative analysis and a tooth to translate the findings to a biomedical sample. Measured linear attenuation coefficients mu and electron densities rho(e) are in good agreement with theoretical values. Improved contrast-to-noise ratios were found in phase contrast compared to attenuation contrast. The combination of both contrast modalities further enables to simultaneously assess information on density and composition of materials with effective atomic numbers (Z) over tilde > 8. In our biomedical example, we demonstrate the possibility to detect differences in mass density and calcium concentration within teeth. (C) 2013 Optical Society of America (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
Optics Express
volume
21
issue
4
pages
4155 - 4166
publisher
OSA
external identifiers
  • wos:000315992600022
  • scopus:84874526406
ISSN
1094-4087
DOI
10.1364/OE.21.004155
language
English
LU publication?
yes
id
ebf1a5ff-e46c-4e37-84ef-4a57bb547e65 (old id 3651124)
date added to LUP
2013-05-02 08:54:56
date last changed
2019-09-11 02:25:11
@article{ebf1a5ff-e46c-4e37-84ef-4a57bb547e65,
  abstract     = {Potential applications of grating-based X-ray phase-contrast imaging are investigated in various fields due to its compatibility with laboratory X-ray sources. So far the method was mainly restricted to X-ray energies below 40 keV, which is too low to examine dense or thick objects, but a routine operation at higher energies is on the brink of realisation. In this study, imaging results obtained at 82 keV are presented. These comprise a test object consisting of well-defined materials for a quantitative analysis and a tooth to translate the findings to a biomedical sample. Measured linear attenuation coefficients mu and electron densities rho(e) are in good agreement with theoretical values. Improved contrast-to-noise ratios were found in phase contrast compared to attenuation contrast. The combination of both contrast modalities further enables to simultaneously assess information on density and composition of materials with effective atomic numbers (Z) over tilde > 8. In our biomedical example, we demonstrate the possibility to detect differences in mass density and calcium concentration within teeth. (C) 2013 Optical Society of America},
  author       = {Willner, Marian and Bech, Martin and Herzen, Julia and Zanette, Irene and Hahn, Dieter and Kenntner, Johannes and Mohr, Juergen and Rack, Alexander and Weitkamp, Timm and Pfeiffer, Franz},
  issn         = {1094-4087},
  language     = {eng},
  number       = {4},
  pages        = {4155--4166},
  publisher    = {OSA},
  series       = {Optics Express},
  title        = {Quantitative X-ray phase-contrast computed tomography at 82 keV},
  url          = {http://dx.doi.org/10.1364/OE.21.004155},
  volume       = {21},
  year         = {2013},
}