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Rutinmässig screening med APTT är inte indicerad före operation

Bian, Li ; Baghaei, Fariba ; Antovic, Jovan ; Fagerberg Blixter, Inger ; Hillarp, Andreas LU ; Strandberg, Karin LU ; Willman, David and L Lindahl, Tomas (2022) In Lakartidningen 119.
Abstract

Activated partial thromboplastin time (APTT) is widely practiced in preoperative screening. The value of using this test to predict the risk of perioperative bleeding is not well documented in Sweden. In this article, a literature review is performed to determine whether unselected APTT testing can predict abnormal perioperative bleeding. The current literature does not support coagulation screening with APTT in routine perioperative bleeding assessment, as preoperative screening with APTT has a low sensitivity for detection of clinically significant bleeding disorder. While a comprehensive bleeding history is crucial, the APTT test should only be performed on patients with a history of increased bleeding tendency. The conclusion of... (More)

Activated partial thromboplastin time (APTT) is widely practiced in preoperative screening. The value of using this test to predict the risk of perioperative bleeding is not well documented in Sweden. In this article, a literature review is performed to determine whether unselected APTT testing can predict abnormal perioperative bleeding. The current literature does not support coagulation screening with APTT in routine perioperative bleeding assessment, as preoperative screening with APTT has a low sensitivity for detection of clinically significant bleeding disorder. While a comprehensive bleeding history is crucial, the APTT test should only be performed on patients with a history of increased bleeding tendency. The conclusion of this literature review is that patients with a negative bleeding history do not require routine screening with APTT prior to surgery, which, if implemented, would lead to a more cost-effective perioperative routine.

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author
; ; ; ; ; ; and
alternative title
Routine screening with APTT is not indicated before surgery
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Blood Coagulation Tests, Hemorrhage, Humans, Mass Screening, Partial Thromboplastin Time, Sweden
in
Lakartidningen
volume
119
article number
21240
publisher
Swedish Medical Association
external identifiers
  • pmid:35713306
ISSN
0023-7205
language
Swedish
LU publication?
no
id
ec4ff6ed-4b6f-4ecd-bcbd-a1d76a65aa43
alternative location
https://lakartidningen.se/wp-content/uploads/2022/04/21240.pdf
date added to LUP
2022-08-29 10:03:13
date last changed
2022-08-30 13:17:07
@article{ec4ff6ed-4b6f-4ecd-bcbd-a1d76a65aa43,
  abstract     = {{<p>Activated partial thromboplastin time (APTT) is widely practiced in preoperative screening. The value of using this test to predict the risk of perioperative bleeding is not well documented in Sweden. In this article, a literature review is performed to determine whether unselected APTT testing can predict abnormal perioperative bleeding. The current literature does not support coagulation screening with APTT in routine perioperative bleeding assessment, as preoperative screening with APTT has a low sensitivity for detection of clinically significant bleeding disorder. While a comprehensive bleeding history is crucial, the APTT test should only be performed on patients with a history of increased bleeding tendency. The conclusion of this literature review is that patients with a negative bleeding history do not require routine screening with APTT prior to surgery, which, if implemented, would lead to a more cost-effective perioperative routine.</p>}},
  author       = {{Bian, Li and Baghaei, Fariba and Antovic, Jovan and Fagerberg Blixter, Inger and Hillarp, Andreas and Strandberg, Karin and Willman, David and L Lindahl, Tomas}},
  issn         = {{0023-7205}},
  keywords     = {{Blood Coagulation Tests; Hemorrhage; Humans; Mass Screening; Partial Thromboplastin Time; Sweden}},
  language     = {{swe}},
  month        = {{06}},
  publisher    = {{Swedish Medical Association}},
  series       = {{Lakartidningen}},
  title        = {{Rutinmässig screening med APTT är inte indicerad före operation}},
  url          = {{https://lakartidningen.se/wp-content/uploads/2022/04/21240.pdf}},
  volume       = {{119}},
  year         = {{2022}},
}