Fast multiecho balanced SSFP metabolite mapping of H-1 and hyperpolarized C-13 compounds
(2009) In Magma 22(4). p.251-256- Abstract
- To investigate the feasibility of multiecho balanced steady-state free precession (bSSFP)-based fast chemical shift mapping hyperpolarized C-13 metabolites. The overall goal was to reduce total imaging time and to increase spatial resolution compared to common chemical shift imaging (CSI). A multiecho bSSFP sequence in combination with an iterative reconstruction algorithm was implemented. H-1 experiments were performed on phantoms and on a human volunteer in order to investigate the feasibility of the method on a system with metabolite maps that are known beforehand. C-13 experiments were performed in vivo on pigs, where CSI images were acquired also for comparison. Chemical shift images of three and four distinct H-1 resonance... (More)
- To investigate the feasibility of multiecho balanced steady-state free precession (bSSFP)-based fast chemical shift mapping hyperpolarized C-13 metabolites. The overall goal was to reduce total imaging time and to increase spatial resolution compared to common chemical shift imaging (CSI). A multiecho bSSFP sequence in combination with an iterative reconstruction algorithm was implemented. H-1 experiments were performed on phantoms and on a human volunteer in order to investigate the feasibility of the method on a system with metabolite maps that are known beforehand. C-13 experiments were performed in vivo on pigs, where CSI images were acquired also for comparison. Chemical shift images of three and four distinct H-1 resonance frequencies as well as chemical shift images of up to five hyperpolarized C-13 metabolites were successfully obtained. Fast metabolite mapping based on multiecho balanced SSFP in combination with an iterative reconstruction approach could successfully separate several H-1 resonances and hyperpolarized C-13 metabolites. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1477222
- author
- Leupold, Jochen ; Månsson, Sven LU ; Petersson, J. Stefan ; Hennig, Juergen and Wieben, Oliver
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Hyperpolarized C-13, IDEAL, Multiecho sequence, Balanced SSFP, Chemical shift imaging
- in
- Magma
- volume
- 22
- issue
- 4
- pages
- 251 - 256
- publisher
- Springer
- external identifiers
-
- wos:000268903800006
- scopus:68849122929
- pmid:19367422
- ISSN
- 1352-8661
- DOI
- 10.1007/s10334-009-0169-z
- language
- English
- LU publication?
- yes
- id
- ed4a475f-72f6-410f-9526-c957cf790817 (old id 1477222)
- date added to LUP
- 2016-04-01 14:25:28
- date last changed
- 2022-05-20 00:23:08
@article{ed4a475f-72f6-410f-9526-c957cf790817, abstract = {{To investigate the feasibility of multiecho balanced steady-state free precession (bSSFP)-based fast chemical shift mapping hyperpolarized C-13 metabolites. The overall goal was to reduce total imaging time and to increase spatial resolution compared to common chemical shift imaging (CSI). A multiecho bSSFP sequence in combination with an iterative reconstruction algorithm was implemented. H-1 experiments were performed on phantoms and on a human volunteer in order to investigate the feasibility of the method on a system with metabolite maps that are known beforehand. C-13 experiments were performed in vivo on pigs, where CSI images were acquired also for comparison. Chemical shift images of three and four distinct H-1 resonance frequencies as well as chemical shift images of up to five hyperpolarized C-13 metabolites were successfully obtained. Fast metabolite mapping based on multiecho balanced SSFP in combination with an iterative reconstruction approach could successfully separate several H-1 resonances and hyperpolarized C-13 metabolites.}}, author = {{Leupold, Jochen and Månsson, Sven and Petersson, J. Stefan and Hennig, Juergen and Wieben, Oliver}}, issn = {{1352-8661}}, keywords = {{Hyperpolarized C-13; IDEAL; Multiecho sequence; Balanced SSFP; Chemical shift imaging}}, language = {{eng}}, number = {{4}}, pages = {{251--256}}, publisher = {{Springer}}, series = {{Magma}}, title = {{Fast multiecho balanced SSFP metabolite mapping of H-1 and hyperpolarized C-13 compounds}}, url = {{http://dx.doi.org/10.1007/s10334-009-0169-z}}, doi = {{10.1007/s10334-009-0169-z}}, volume = {{22}}, year = {{2009}}, }