Analysis of age at detection and outcomes of dense unilateral congenital cataract surgery for children on the paediatric cataract register
(2023) In Acta Paediatrica, International Journal of Paediatrics 112(2). p.277-285- Abstract
Aim: Analysis of age at time of detection and surgery of dense unilateral cataract and investigation of best-corrected visual acuity (BCVA) in a nationwide register-based cohort study, based on the routine of maternity ward eye screening. Methods: Data were derived from the Paediatric Cataract Register (PECARE). All children (n = 54) diagnosed with dense congenital unilateral cataract between January 2007 and September 2014 who had surgery before 1 year of age, and for whom 5-year follow-up records were available, were included. Results: The majority, 35/54 (65%), were detected and operated on before age 6 weeks and 30/35 (86%) were referred from maternity wards. Visual acuity (VA) ≥ 0.5 (decimal, 0.3 logMAR) was found in 7/53 (13%) of... (More)
Aim: Analysis of age at time of detection and surgery of dense unilateral cataract and investigation of best-corrected visual acuity (BCVA) in a nationwide register-based cohort study, based on the routine of maternity ward eye screening. Methods: Data were derived from the Paediatric Cataract Register (PECARE). All children (n = 54) diagnosed with dense congenital unilateral cataract between January 2007 and September 2014 who had surgery before 1 year of age, and for whom 5-year follow-up records were available, were included. Results: The majority, 35/54 (65%), were detected and operated on before age 6 weeks and 30/35 (86%) were referred from maternity wards. Visual acuity (VA) ≥ 0.5 (decimal, 0.3 logMAR) was found in 7/53 (13%) of the cohort at age 5 years; further, 19 children achieved VA ≥ 0.1 (decimal, 1.0 logMAR) (36%) and 19 children VA < 0.05 (decimal, 1.30 logMAR) (36%). Ten-year follow-up records were available for 17/53 (32%) children; 1/17 (6%) achieved VA ≥ 0.5 (decimal, 0.3 logMAR), 4/17 (24%) VA ≥ 0.3–<0.5 (decimal, 0.52–0.30 logMAR), 3/17 (18%) VA ≥ 0.05–0.1 (decimal, 1.30–1.0 logMAR) and 10/17 (59%) VA < 0.05 (decimal, 1.30 logMAR). Conclusion: A total of 90% of the children were detected with cataract within 100 days of birth and 80% were operated on within this period. This study showed better visual acuity in those treated for dense unilateral cataracts than previously reported in an earlier Swedish cohort study.
(Less)
- author
- Wackerberg, David ; Nyström, Alf LU ; Haargaard, Birgitte ; Rosensvärd, Annika ; Tornqvist, Kristina LU ; Borg, Lovisa ; Kugelberg, Maria ; Gyllén, Jenny and Magnusson, Gunilla
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- congenital unilateral cataract, early detection of disease, screening, treatment outcome, visual acuity
- in
- Acta Paediatrica, International Journal of Paediatrics
- volume
- 112
- issue
- 2
- pages
- 9 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85143359638
- pmid:36366873
- ISSN
- 0803-5253
- DOI
- 10.1111/apa.16591
- language
- English
- LU publication?
- yes
- id
- ed53c015-6b16-4b62-b4af-2a98a124376a
- date added to LUP
- 2023-01-30 12:52:12
- date last changed
- 2024-06-09 11:18:57
@article{ed53c015-6b16-4b62-b4af-2a98a124376a,
abstract = {{<p>Aim: Analysis of age at time of detection and surgery of dense unilateral cataract and investigation of best-corrected visual acuity (BCVA) in a nationwide register-based cohort study, based on the routine of maternity ward eye screening. Methods: Data were derived from the Paediatric Cataract Register (PECARE). All children (n = 54) diagnosed with dense congenital unilateral cataract between January 2007 and September 2014 who had surgery before 1 year of age, and for whom 5-year follow-up records were available, were included. Results: The majority, 35/54 (65%), were detected and operated on before age 6 weeks and 30/35 (86%) were referred from maternity wards. Visual acuity (VA) ≥ 0.5 (decimal, 0.3 logMAR) was found in 7/53 (13%) of the cohort at age 5 years; further, 19 children achieved VA ≥ 0.1 (decimal, 1.0 logMAR) (36%) and 19 children VA < 0.05 (decimal, 1.30 logMAR) (36%). Ten-year follow-up records were available for 17/53 (32%) children; 1/17 (6%) achieved VA ≥ 0.5 (decimal, 0.3 logMAR), 4/17 (24%) VA ≥ 0.3–<0.5 (decimal, 0.52–0.30 logMAR), 3/17 (18%) VA ≥ 0.05–0.1 (decimal, 1.30–1.0 logMAR) and 10/17 (59%) VA < 0.05 (decimal, 1.30 logMAR). Conclusion: A total of 90% of the children were detected with cataract within 100 days of birth and 80% were operated on within this period. This study showed better visual acuity in those treated for dense unilateral cataracts than previously reported in an earlier Swedish cohort study.</p>}},
author = {{Wackerberg, David and Nyström, Alf and Haargaard, Birgitte and Rosensvärd, Annika and Tornqvist, Kristina and Borg, Lovisa and Kugelberg, Maria and Gyllén, Jenny and Magnusson, Gunilla}},
issn = {{0803-5253}},
keywords = {{congenital unilateral cataract; early detection of disease; screening; treatment outcome; visual acuity}},
language = {{eng}},
number = {{2}},
pages = {{277--285}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Paediatrica, International Journal of Paediatrics}},
title = {{Analysis of age at detection and outcomes of dense unilateral congenital cataract surgery for children on the paediatric cataract register}},
url = {{http://dx.doi.org/10.1111/apa.16591}},
doi = {{10.1111/apa.16591}},
volume = {{112}},
year = {{2023}},
}