Chromosome aberrations in psoriatic patients treated with arsenic
(1979) In Human Genetics 48(1). p.1-6- Abstract
A significantly increased frequency of chromosomal aberrations was found in lymphocytes from eight psoriatic patients previously treated with arsenic than in lymphocytes from eight psoriatics with no such previous treatment. In most patients the arsenic therapy was discontinued more than 15 years ago. In the arsenic-treated group a statistically significant heterogeneity was found with respect to the frequency of aberrations. The frequency of sister chromatid exchange was not increased in the arsenic-treated patients.
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https://lup.lub.lu.se/record/ed8427c8-12b3-4abb-8d81-b701f97b1f59
- author
- Nordenson, I ; Salmonsson, S ; Brun, E LU and Beckman, G
- publishing date
- 1979-04-17
- type
- Contribution to journal
- publication status
- published
- keywords
- Adult, Aged, Arsenic/adverse effects, Chromatids/drug effects, Chromosome Aberrations, Crossing Over, Genetic/drug effects, Female, Humans, Lymphocytes/ultrastructure, Male, Middle Aged, Psoriasis/drug therapy, Time Factors
- in
- Human Genetics
- volume
- 48
- issue
- 1
- pages
- 6 pages
- publisher
- Springer
- external identifiers
-
- scopus:0018286961
- pmid:457124
- ISSN
- 0340-6717
- language
- English
- LU publication?
- no
- id
- ed8427c8-12b3-4abb-8d81-b701f97b1f59
- date added to LUP
- 2019-07-01 14:09:01
- date last changed
- 2024-01-01 15:06:19
@article{ed8427c8-12b3-4abb-8d81-b701f97b1f59, abstract = {{<p>A significantly increased frequency of chromosomal aberrations was found in lymphocytes from eight psoriatic patients previously treated with arsenic than in lymphocytes from eight psoriatics with no such previous treatment. In most patients the arsenic therapy was discontinued more than 15 years ago. In the arsenic-treated group a statistically significant heterogeneity was found with respect to the frequency of aberrations. The frequency of sister chromatid exchange was not increased in the arsenic-treated patients.</p>}}, author = {{Nordenson, I and Salmonsson, S and Brun, E and Beckman, G}}, issn = {{0340-6717}}, keywords = {{Adult; Aged; Arsenic/adverse effects; Chromatids/drug effects; Chromosome Aberrations; Crossing Over, Genetic/drug effects; Female; Humans; Lymphocytes/ultrastructure; Male; Middle Aged; Psoriasis/drug therapy; Time Factors}}, language = {{eng}}, month = {{04}}, number = {{1}}, pages = {{1--6}}, publisher = {{Springer}}, series = {{Human Genetics}}, title = {{Chromosome aberrations in psoriatic patients treated with arsenic}}, volume = {{48}}, year = {{1979}}, }