Abnormal oral vascular network pattern geometry: A new clinical sign of Down syndrome
(2006) In Journal of Pediatrics 148(1). p.132-137- Abstract
- Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension (P <= .0006) for the oral vascular networks of patients (n = 14) and their unaffected parents. This newly recognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/419393
- author
- Latini, G ; Bianciardi, G ; Parrini, S ; Laurini, Ricardo LU and De Felice, C
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Pediatrics
- volume
- 148
- issue
- 1
- pages
- 132 - 137
- publisher
- Academic Press
- external identifiers
-
- wos:000234954900029
- pmid:16423614
- scopus:30744443845
- pmid:16423614
- ISSN
- 1097-6833
- DOI
- 10.1016/j.jpeds.2005.08.049
- language
- English
- LU publication?
- yes
- id
- ee60f289-94f3-488a-9751-61a2a351c270 (old id 419393)
- date added to LUP
- 2016-04-01 11:39:37
- date last changed
- 2022-01-26 08:22:23
@article{ee60f289-94f3-488a-9751-61a2a351c270, abstract = {{Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension (P <= .0006) for the oral vascular networks of patients (n = 14) and their unaffected parents. This newly recognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.}}, author = {{Latini, G and Bianciardi, G and Parrini, S and Laurini, Ricardo and De Felice, C}}, issn = {{1097-6833}}, language = {{eng}}, number = {{1}}, pages = {{132--137}}, publisher = {{Academic Press}}, series = {{Journal of Pediatrics}}, title = {{Abnormal oral vascular network pattern geometry: A new clinical sign of Down syndrome}}, url = {{http://dx.doi.org/10.1016/j.jpeds.2005.08.049}}, doi = {{10.1016/j.jpeds.2005.08.049}}, volume = {{148}}, year = {{2006}}, }