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Gastroduodenal morphology and related symptoms in chronic alcoholics

Hauge, T ; Persson, J and Nilsson, A LU (1997) In Diagnostic and Therapeutic Endoscopy 4(1). p.29-33
Abstract

Twenty-four chronic alcoholics admitted to hospital for detoxification after a drinking spree were examined by upper gastrointestinal endoscopy. Biopsy specimens were taken from corpus/fundus, antrum and duodenum for tissue histology (eosin stain). From the duodenum villus index and ultrastructure (scanning electron microscopy, SEM) were also performed. As a control group 12 subjectively healthy non-alcoholics referred to upper gastrointestinal endoscopy mainly for dyspepsia were chosen.Gastrointestinal symptoms were common in alcoholics (88%). Endoscopic and histological gastroduodenitis were not more common in the alcohol group. There was no correlation between gastrointestinal symptoms and endoscopic or histological gastroduodenitis... (More)

Twenty-four chronic alcoholics admitted to hospital for detoxification after a drinking spree were examined by upper gastrointestinal endoscopy. Biopsy specimens were taken from corpus/fundus, antrum and duodenum for tissue histology (eosin stain). From the duodenum villus index and ultrastructure (scanning electron microscopy, SEM) were also performed. As a control group 12 subjectively healthy non-alcoholics referred to upper gastrointestinal endoscopy mainly for dyspepsia were chosen.Gastrointestinal symptoms were common in alcoholics (88%). Endoscopic and histological gastroduodenitis were not more common in the alcohol group. There was no correlation between gastrointestinal symptoms and endoscopic or histological gastroduodenitis in both groups. In the duodenum, 50% of the alcoholics and 82% in the control group had alterations by scanning electron microscopy. Ten of the 11 alcoholics with an abnormal ultrastructure had diarrhoea. In the control group dyspepsia (ulcus suspect) was correlated to a pathological SEM.

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author
; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Diagnostic and Therapeutic Endoscopy
volume
4
issue
1
pages
5 pages
publisher
Harwood Academic
external identifiers
  • pmid:18493448
  • scopus:0030794756
ISSN
1070-3608
DOI
10.1155/DTE.4.29
language
English
LU publication?
no
id
ef00785a-7e50-44f1-9cb5-9f4bfe127423
date added to LUP
2019-09-19 14:44:42
date last changed
2024-01-01 20:52:59
@article{ef00785a-7e50-44f1-9cb5-9f4bfe127423,
  abstract     = {{<p>Twenty-four chronic alcoholics admitted to hospital for detoxification after a drinking spree were examined by upper gastrointestinal endoscopy. Biopsy specimens were taken from corpus/fundus, antrum and duodenum for tissue histology (eosin stain). From the duodenum villus index and ultrastructure (scanning electron microscopy, SEM) were also performed. As a control group 12 subjectively healthy non-alcoholics referred to upper gastrointestinal endoscopy mainly for dyspepsia were chosen.Gastrointestinal symptoms were common in alcoholics (88%). Endoscopic and histological gastroduodenitis were not more common in the alcohol group. There was no correlation between gastrointestinal symptoms and endoscopic or histological gastroduodenitis in both groups. In the duodenum, 50% of the alcoholics and 82% in the control group had alterations by scanning electron microscopy. Ten of the 11 alcoholics with an abnormal ultrastructure had diarrhoea. In the control group dyspepsia (ulcus suspect) was correlated to a pathological SEM.</p>}},
  author       = {{Hauge, T and Persson, J and Nilsson, A}},
  issn         = {{1070-3608}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{29--33}},
  publisher    = {{Harwood Academic}},
  series       = {{Diagnostic and Therapeutic Endoscopy}},
  title        = {{Gastroduodenal morphology and related symptoms in chronic alcoholics}},
  url          = {{http://dx.doi.org/10.1155/DTE.4.29}},
  doi          = {{10.1155/DTE.4.29}},
  volume       = {{4}},
  year         = {{1997}},
}