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Antimicrobial Peptides : Roles in Periodontal Health and Disease

Jönsson, Daniel LU (2017) p.97-110
Abstract
Why do cockroaches and rats survive in sewers and other extremely challenging conditions? The answer is that through evolution they have been equipped with antimicrobial peptides (AMPs) that protect them from microbiological insult. In the case of cockroaches and rats, the AMPs are very potent, allowing for these challenging environments [1–3]. AMPs are the most ancient and primitive arm of the human immune system and are expressed in mammals, insects, fungus, trees—virtually every multicellular organism that coexist with bacteria, including bacteria. AMPs cover the outer barriers of our body, such as epithelium and skin, enabling us to live in coexistence with what some consider a complex organ—the microbiome [4]. As we now, through the... (More)
Why do cockroaches and rats survive in sewers and other extremely challenging conditions? The answer is that through evolution they have been equipped with antimicrobial peptides (AMPs) that protect them from microbiological insult. In the case of cockroaches and rats, the AMPs are very potent, allowing for these challenging environments [1–3]. AMPs are the most ancient and primitive arm of the human immune system and are expressed in mammals, insects, fungus, trees—virtually every multicellular organism that coexist with bacteria, including bacteria. AMPs cover the outer barriers of our body, such as epithelium and skin, enabling us to live in coexistence with what some consider a complex organ—the microbiome [4]. As we now, through the technological advancements in microbiology, start to comprehend the complexity of the microbiome, we can also appreciate the complexity of the AMP-profile. (Less)
Please use this url to cite or link to this publication:
author
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Pathogenesis of Periodontal Diseases : Biological Concepts for Clinicians - Biological Concepts for Clinicians
editor
Bostanci, Nagihan and Belibasakis, Georgios N.
pages
97 - 110
publisher
Springer
ISBN
978-3-319-53735-1
978-3-319-53737-5
language
English
LU publication?
no
id
f0b291b9-4267-4e6d-9e1d-ce7bb88a4447
alternative location
https://link.springer.com/chapter/10.1007/978-3-319-53737-5_8
date added to LUP
2024-07-04 11:16:52
date last changed
2024-07-04 11:16:52
@inbook{f0b291b9-4267-4e6d-9e1d-ce7bb88a4447,
  abstract     = {{Why do cockroaches and rats survive in sewers and other extremely challenging conditions? The answer is that through evolution they have been equipped with antimicrobial peptides (AMPs) that protect them from microbiological insult. In the case of cockroaches and rats, the AMPs are very potent, allowing for these challenging environments [1–3]. AMPs are the most ancient and primitive arm of the human immune system and are expressed in mammals, insects, fungus, trees—virtually every multicellular organism that coexist with bacteria, including bacteria. AMPs cover the outer barriers of our body, such as epithelium and skin, enabling us to live in coexistence with what some consider a complex organ—the microbiome [4]. As we now, through the technological advancements in microbiology, start to comprehend the complexity of the microbiome, we can also appreciate the complexity of the AMP-profile.}},
  author       = {{Jönsson, Daniel}},
  booktitle    = {{Pathogenesis of Periodontal Diseases : Biological Concepts for Clinicians}},
  editor       = {{Bostanci, Nagihan and Belibasakis, Georgios N.}},
  isbn         = {{978-3-319-53735-1}},
  language     = {{eng}},
  month        = {{09}},
  pages        = {{97--110}},
  publisher    = {{Springer}},
  title        = {{Antimicrobial Peptides : Roles in Periodontal Health and Disease}},
  url          = {{https://link.springer.com/chapter/10.1007/978-3-319-53737-5_8}},
  year         = {{2017}},
}