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Acoustic Radiation Forces Produced by Sharp-Edge Structures in Microfluidic Systems

Doinikov, Alexander A ; Gerlt, Michael S LU orcid and Dual, Jürg (2020) In Physical Review Letters 124(15).
Abstract

We study sharp-edge structures that are used in microfluidic systems for particle and cell manipulation. Experiments show that oscillating sharp edges can attract or repel particles suspended in a microfluidic channel. This effect is caused by acoustic radiation forces induced by sharp edges. We propose an analytical theory that allows one to evaluate the acoustic radiation force produced by a sharp-edge structure on elastic particles and to study which parameters govern the interaction of particles with a sharp-edge structure, forcing them to be attracted in one situation and to be repelled in another situation. The proposed theory gives foundations for the design of microfluidic systems making use of sharp edges for particle trapping.... (More)

We study sharp-edge structures that are used in microfluidic systems for particle and cell manipulation. Experiments show that oscillating sharp edges can attract or repel particles suspended in a microfluidic channel. This effect is caused by acoustic radiation forces induced by sharp edges. We propose an analytical theory that allows one to evaluate the acoustic radiation force produced by a sharp-edge structure on elastic particles and to study which parameters govern the interaction of particles with a sharp-edge structure, forcing them to be attracted in one situation and to be repelled in another situation. The proposed theory gives foundations for the design of microfluidic systems making use of sharp edges for particle trapping. We also provide experimental data to validate the theory.

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Please use this url to cite or link to this publication:
author
; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Physical Review Letters
volume
124
issue
15
article number
154501
publisher
American Physical Society
external identifiers
  • pmid:32357031
  • scopus:85084379744
ISSN
1079-7114
DOI
10.1103/PhysRevLett.124.154501
language
English
LU publication?
no
id
f0c4bb2d-e345-4ee9-b60e-73f68797453a
date added to LUP
2023-04-12 09:25:00
date last changed
2024-04-05 18:19:33
@article{f0c4bb2d-e345-4ee9-b60e-73f68797453a,
  abstract     = {{<p>We study sharp-edge structures that are used in microfluidic systems for particle and cell manipulation. Experiments show that oscillating sharp edges can attract or repel particles suspended in a microfluidic channel. This effect is caused by acoustic radiation forces induced by sharp edges. We propose an analytical theory that allows one to evaluate the acoustic radiation force produced by a sharp-edge structure on elastic particles and to study which parameters govern the interaction of particles with a sharp-edge structure, forcing them to be attracted in one situation and to be repelled in another situation. The proposed theory gives foundations for the design of microfluidic systems making use of sharp edges for particle trapping. We also provide experimental data to validate the theory.</p>}},
  author       = {{Doinikov, Alexander A and Gerlt, Michael S and Dual, Jürg}},
  issn         = {{1079-7114}},
  language     = {{eng}},
  month        = {{04}},
  number       = {{15}},
  publisher    = {{American Physical Society}},
  series       = {{Physical Review Letters}},
  title        = {{Acoustic Radiation Forces Produced by Sharp-Edge Structures in Microfluidic Systems}},
  url          = {{http://dx.doi.org/10.1103/PhysRevLett.124.154501}},
  doi          = {{10.1103/PhysRevLett.124.154501}},
  volume       = {{124}},
  year         = {{2020}},
}