Adverse events within 1 year after surgical and percutaneous closure of atrial septal defects in preterm children
(2019) In Cardiology in the Young 29(5). p.626-636- Abstract
Introduction: Atrial septal defect is the third most common CHD. A hemodynamically significant atrial septal defect causes volume overload of the right side of the heart. Preterm children may suffer from both pulmonary and cardiac comorbidities, including altered myocardial function. The aim of this study was to compare the rate of adverse events following atrial septal defect closure in preterm- and term-born children.Method: We performed a retrospective cohort study including children born in Sweden, who had a surgical or percutaneous atrial septal defect closure at the children's hospitals in Lund and Stockholm, between 2000 and 2014, assessing time to the first event within 1 month or 1 year. We analysed differences in the number of... (More)
Introduction: Atrial septal defect is the third most common CHD. A hemodynamically significant atrial septal defect causes volume overload of the right side of the heart. Preterm children may suffer from both pulmonary and cardiac comorbidities, including altered myocardial function. The aim of this study was to compare the rate of adverse events following atrial septal defect closure in preterm- and term-born children.Method: We performed a retrospective cohort study including children born in Sweden, who had a surgical or percutaneous atrial septal defect closure at the children's hospitals in Lund and Stockholm, between 2000 and 2014, assessing time to the first event within 1 month or 1 year. We analysed differences in the number of and the time to events between the preterm and term cohort using the Kaplan-Meier survival curve, a generalised model applying zero-inflated Poisson distribution and Gary-Anderson's method.Results: Overall, 413 children were included in the study. Of these, 93 (22.5%) were born prematurely. The total number of adverse events was 178 (110 minor and 68 major). There was no difference between the cohorts in the number of events, whether within 1 month or within a year, between major (p = 0.69) and minor (p = 0.84) events or frequencies of multiple events (p = 0.92).Conclusion: Despite earlier procedural age, larger atrial septal defects, and higher comorbidity than term children, preterm children appear to have comparable risk for complications during the first year after surgical or percutaneous closure.
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- author
- Tanghöj, Gustaf ; Liuba, Petru LU ; Sjöberg, Gunnar ; Rydberg, Annika and Naumburg, Estelle
- publishing date
- 2019-05-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- atrial septal defect, Child, complications, percutaneous closure, surgical closure
- in
- Cardiology in the Young
- volume
- 29
- issue
- 5
- pages
- 626 - 636
- publisher
- Cambridge University Press
- external identifiers
-
- scopus:85066839690
- pmid:31159892
- ISSN
- 1047-9511
- DOI
- 10.1017/S1047951119000350
- language
- English
- LU publication?
- no
- additional info
- Publisher Copyright: © Cambridge University Press 2019.
- id
- f0c5635d-1989-4fa1-b729-820b31588c8f
- date added to LUP
- 2024-07-13 09:51:54
- date last changed
- 2024-07-17 13:53:26
@article{f0c5635d-1989-4fa1-b729-820b31588c8f,
abstract = {{<p>Introduction: Atrial septal defect is the third most common CHD. A hemodynamically significant atrial septal defect causes volume overload of the right side of the heart. Preterm children may suffer from both pulmonary and cardiac comorbidities, including altered myocardial function. The aim of this study was to compare the rate of adverse events following atrial septal defect closure in preterm- and term-born children.Method: We performed a retrospective cohort study including children born in Sweden, who had a surgical or percutaneous atrial septal defect closure at the children's hospitals in Lund and Stockholm, between 2000 and 2014, assessing time to the first event within 1 month or 1 year. We analysed differences in the number of and the time to events between the preterm and term cohort using the Kaplan-Meier survival curve, a generalised model applying zero-inflated Poisson distribution and Gary-Anderson's method.Results: Overall, 413 children were included in the study. Of these, 93 (22.5%) were born prematurely. The total number of adverse events was 178 (110 minor and 68 major). There was no difference between the cohorts in the number of events, whether within 1 month or within a year, between major (p = 0.69) and minor (p = 0.84) events or frequencies of multiple events (p = 0.92).Conclusion: Despite earlier procedural age, larger atrial septal defects, and higher comorbidity than term children, preterm children appear to have comparable risk for complications during the first year after surgical or percutaneous closure.</p>}},
author = {{Tanghöj, Gustaf and Liuba, Petru and Sjöberg, Gunnar and Rydberg, Annika and Naumburg, Estelle}},
issn = {{1047-9511}},
keywords = {{atrial septal defect; Child; complications; percutaneous closure; surgical closure}},
language = {{eng}},
month = {{05}},
number = {{5}},
pages = {{626--636}},
publisher = {{Cambridge University Press}},
series = {{Cardiology in the Young}},
title = {{Adverse events within 1 year after surgical and percutaneous closure of atrial septal defects in preterm children}},
url = {{http://dx.doi.org/10.1017/S1047951119000350}},
doi = {{10.1017/S1047951119000350}},
volume = {{29}},
year = {{2019}},
}