Efficient, mild and completely regioselective synthesis of substituted pyridines
Andersson, Hans ; Sainte-Luce Banchelin, Thomas ; Das, Sajal ; Olsson, Roger LU
and Almqvist, Fredrik
(2010)
In Chemical Communications
46(19).
p.3384-3386
- Abstract
Addition of Grignard reagents to pyridine N-oxides in THF at low temperature (-78 to -20 °C) and treatment with TFAA provides an efficient general procedure for synthesis of substituted pyridines. The method is compatible with a range of functional groups such as esters, halogens and nitriles.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/f0e01963-249d-407b-9e39-6bdbff4f65f7
- author
- Andersson, Hans
; Sainte-Luce Banchelin, Thomas
; Das, Sajal
; Olsson, Roger
LU
and Almqvist, Fredrik
- publishing date
- 2010-05-13
- type
- Contribution to journal
- publication status
- published
- in
- Chemical Communications
- volume
- 46
- issue
- 19
- pages
- 3 pages
- publisher
- Royal Society of Chemistry
- external identifiers
-
- pmid:20428521
- scopus:77951983456
- ISSN
- 1359-7345
- DOI
- 10.1039/c000748j
- language
- English
- LU publication?
- no
- id
- f0e01963-249d-407b-9e39-6bdbff4f65f7
- date added to LUP
- 2019-10-02 09:39:21
- date last changed
- 2025-10-14 11:03:01
@article{f0e01963-249d-407b-9e39-6bdbff4f65f7,
abstract = {{<p>Addition of Grignard reagents to pyridine N-oxides in THF at low temperature (-78 to -20 °C) and treatment with TFAA provides an efficient general procedure for synthesis of substituted pyridines. The method is compatible with a range of functional groups such as esters, halogens and nitriles.</p>}},
author = {{Andersson, Hans and Sainte-Luce Banchelin, Thomas and Das, Sajal and Olsson, Roger and Almqvist, Fredrik}},
issn = {{1359-7345}},
language = {{eng}},
month = {{05}},
number = {{19}},
pages = {{3384--3386}},
publisher = {{Royal Society of Chemistry}},
series = {{Chemical Communications}},
title = {{Efficient, mild and completely regioselective synthesis of substituted pyridines}},
url = {{http://dx.doi.org/10.1039/c000748j}},
doi = {{10.1039/c000748j}},
volume = {{46}},
year = {{2010}},
}