The use of N-terminal pro-brain natriuretic Peptide to evaluate vascular disease in elderly patients with mental illness.
(2012) In Dementia and Geriatric Cognitive Disorders Extra 2. p.10-18- Abstract
- BACKGROUND:
Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment.
METHOD:
In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in different subgroups of vascular disease.
RESULTS AND CONCLUSION:
Patients with vascular disease and elevated serum NT-proBNP level had a lower cognition level, shorter survival time, lower renal function and a higher percentage of pathological brain imaging than patients with vascular disease... (More) - BACKGROUND:
Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment.
METHOD:
In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in different subgroups of vascular disease.
RESULTS AND CONCLUSION:
Patients with vascular disease and elevated serum NT-proBNP level had a lower cognition level, shorter survival time, lower renal function and a higher percentage of pathological brain imaging than patients with vascular disease and normal NT-proBNP level. Thus, elevated serum NT-proBNP level might be helpful to detect patients who have a more severe cardiovascular disease. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2519765
- author
- Nilsson, Karin LU ; Gustafson, Lars LU and Hultberg, Björn LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Dementia and Geriatric Cognitive Disorders Extra
- volume
- 2
- pages
- 10 - 18
- publisher
- Karger
- external identifiers
-
- pmid:22479261
- ISSN
- 1664-5464
- DOI
- 10.1159/000334997
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Clinical Chemistry and Pharmacology (013250300), Department of Psychogeriatrics (013304000)
- id
- f11d08e8-ad91-4917-ae93-8e3b89b2c1b0 (old id 2519765)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22479261?dopt=Abstract
- date added to LUP
- 2016-04-04 09:11:40
- date last changed
- 2018-11-21 20:51:25
@article{f11d08e8-ad91-4917-ae93-8e3b89b2c1b0, abstract = {{BACKGROUND:<br/><br> Serum N-terminal pro-brain natriuretic peptide (NT-proBNP) is regarded as a sensitive marker of cardiovascular disease. Vascular disease plays an important role in cognitive impairment.<br/><br> <br/><br> METHOD:<br/><br> In 447 elderly patients with mental illness, serum NT-proBNP level and the presence or absence of vascular disease according to the medical record were used to categorize patients in different subgroups of vascular disease.<br/><br> <br/><br> RESULTS AND CONCLUSION:<br/><br> Patients with vascular disease and elevated serum NT-proBNP level had a lower cognition level, shorter survival time, lower renal function and a higher percentage of pathological brain imaging than patients with vascular disease and normal NT-proBNP level. Thus, elevated serum NT-proBNP level might be helpful to detect patients who have a more severe cardiovascular disease.}}, author = {{Nilsson, Karin and Gustafson, Lars and Hultberg, Björn}}, issn = {{1664-5464}}, language = {{eng}}, pages = {{10--18}}, publisher = {{Karger}}, series = {{Dementia and Geriatric Cognitive Disorders Extra}}, title = {{The use of N-terminal pro-brain natriuretic Peptide to evaluate vascular disease in elderly patients with mental illness.}}, url = {{http://dx.doi.org/10.1159/000334997}}, doi = {{10.1159/000334997}}, volume = {{2}}, year = {{2012}}, }