Defined shapes of carotid artery calcifications on panoramic radiographs correlate with specific signs of cardiovascular disease on ultrasound examination
(2024) In Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology- Abstract
Objective: The aim was to optimize diagnostics for carotid artery calcifications (CACs) on panoramic radiographs (PRs) to identify cardiovascular disease (CVD) by investigating how 4 defined CAC shapes are associated with ultrasound (US) findings indicating CVD. Study Design: The study included 414 participants (802 neck sides) from the Malmö Offspring Dental Study, examined with PRs. The PRs were assessed for CAC shapes stratified into 4 categories: single, scattered, vessel-width defining, and vessel-outlining. The carotid arteries were examined with US for signs of CVD: the presence of plaques, largest individual area of a plaque, number of plaques, and percentage reduction of the lumen. Associations between the different CAC... (More)
Objective: The aim was to optimize diagnostics for carotid artery calcifications (CACs) on panoramic radiographs (PRs) to identify cardiovascular disease (CVD) by investigating how 4 defined CAC shapes are associated with ultrasound (US) findings indicating CVD. Study Design: The study included 414 participants (802 neck sides) from the Malmö Offspring Dental Study, examined with PRs. The PRs were assessed for CAC shapes stratified into 4 categories: single, scattered, vessel-width defining, and vessel-outlining. The carotid arteries were examined with US for signs of CVD: the presence of plaques, largest individual area of a plaque, number of plaques, and percentage reduction of the lumen. Associations between the different CAC categories and US characteristics were analyzed. Results: All categories of CAC were significantly associated with a higher degree of US findings indicating CVD compared with no CAC (P < .001). The most significant differences were found for vessel-outlining CAC, with the mean of the largest individual plaque area of 17.9 vs 2.3 mm2, mean number of plaques 1.6 vs 0.2, and mean percentage reduction of the lumen 24.1% vs 3.5% (all P < .001). Conclusions: Independent of shape, CACs detected on PRs were associated with a higher degree of US findings of CVD. This was most pronounced for vessel-outlining CAC. With refined differential diagnostics of CACs in PRs, dentists may contribute to improved identification of patients in need of cardiovascular prevention.
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- author
- Bladh, Magnus ; Gustafsson, Nils ; Engström, Gunnar LU ; Kennbäck, Cecilia LU ; Klinge, Björn ; Nilsson, Peter M. LU ; Jönsson, Daniel LU and Levring Jäghagen, Eva
- organization
- publishing date
- 2024
- type
- Contribution to journal
- publication status
- epub
- subject
- in
- Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
- publisher
- Elsevier
- external identifiers
-
- pmid:38320892
- scopus:85183975366
- ISSN
- 2212-4403
- DOI
- 10.1016/j.oooo.2023.12.783
- language
- English
- LU publication?
- yes
- id
- f1a0f23a-1a52-42e3-bbc5-1a7de68de632
- date added to LUP
- 2024-02-27 12:20:23
- date last changed
- 2024-04-26 15:44:57
@article{f1a0f23a-1a52-42e3-bbc5-1a7de68de632,
abstract = {{<p>Objective: The aim was to optimize diagnostics for carotid artery calcifications (CACs) on panoramic radiographs (PRs) to identify cardiovascular disease (CVD) by investigating how 4 defined CAC shapes are associated with ultrasound (US) findings indicating CVD. Study Design: The study included 414 participants (802 neck sides) from the Malmö Offspring Dental Study, examined with PRs. The PRs were assessed for CAC shapes stratified into 4 categories: single, scattered, vessel-width defining, and vessel-outlining. The carotid arteries were examined with US for signs of CVD: the presence of plaques, largest individual area of a plaque, number of plaques, and percentage reduction of the lumen. Associations between the different CAC categories and US characteristics were analyzed. Results: All categories of CAC were significantly associated with a higher degree of US findings indicating CVD compared with no CAC (P < .001). The most significant differences were found for vessel-outlining CAC, with the mean of the largest individual plaque area of 17.9 vs 2.3 mm<sup>2</sup>, mean number of plaques 1.6 vs 0.2, and mean percentage reduction of the lumen 24.1% vs 3.5% (all P < .001). Conclusions: Independent of shape, CACs detected on PRs were associated with a higher degree of US findings of CVD. This was most pronounced for vessel-outlining CAC. With refined differential diagnostics of CACs in PRs, dentists may contribute to improved identification of patients in need of cardiovascular prevention.</p>}},
author = {{Bladh, Magnus and Gustafsson, Nils and Engström, Gunnar and Kennbäck, Cecilia and Klinge, Björn and Nilsson, Peter M. and Jönsson, Daniel and Levring Jäghagen, Eva}},
issn = {{2212-4403}},
language = {{eng}},
publisher = {{Elsevier}},
series = {{Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology}},
title = {{Defined shapes of carotid artery calcifications on panoramic radiographs correlate with specific signs of cardiovascular disease on ultrasound examination}},
url = {{http://dx.doi.org/10.1016/j.oooo.2023.12.783}},
doi = {{10.1016/j.oooo.2023.12.783}},
year = {{2024}},
}