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Mapping the inversion efficiency (finv): Comparison between adiabatic pulses for use in MP2RAGE-based T1-mapping

Olsson, Hampus LU and Helms, Gunther LU orcid (2022) Joint Annual Meeting ISMRM-ESMRMB 2022 In Proc Intl Soc Magn Reson Med 30.
Abstract

Accuracy in MP2RAGE-based T1-mapping
relies on knowledge of the imperfect inversion efficiency (finv)
of the inversion pulse. Here we map the inversion efficiency of different
adiabatic inversion pulses in human brain at 7T. We identified a mean finv=0.86,
which is substantially lower than the finv=0.96 typically
assumed in MP2RAGE. We further observed a lower finv in white
matter (WM) than in the rest of the cerebrum. Subsequent T1
estimates differed by approximately 90 ms in WM and 230 ms in GM when assuming
either finv=0.86 or finv=0.96.

Please use this url to cite or link to this publication:
author
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organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition
series title
Proc Intl Soc Magn Reson Med
volume
30
article number
372
publisher
International Society for Magnetic Resonance in Medicine
conference name
Joint Annual Meeting ISMRM-ESMRMB 2022
conference location
London, United Kingdom
conference dates
2022-05-07 - 2022-05-12
ISSN
1545-4428
project
Multiparametric mapping of the brain at 7T using gradient echoes
Gradient echo-based quantitative MRI of human brain at 7T
language
English
LU publication?
yes
id
f2d107ea-1e81-491d-914b-46b2628bcbd5
alternative location
https://index.mirasmart.com/ISMRM2022/PDFfiles/0372.html
date added to LUP
2022-02-07 14:58:41
date last changed
2022-11-30 02:37:52
@inproceedings{f2d107ea-1e81-491d-914b-46b2628bcbd5,
  abstract     = {{<p class="MsoNormal">Accuracy in MP2RAGE-based <i>T</i><sub>1</sub>-mapping<br>
relies on knowledge of the imperfect inversion efficiency (<i>f</i><sub>inv</sub>)<br>
of the inversion pulse. Here we map the inversion efficiency of different<br>
adiabatic inversion pulses in human brain at 7T. We identified a mean <i>f</i><sub>inv</sub>=0.86,<br>
which is substantially lower than the <i>f</i><sub>inv</sub>=0.96 typically<br>
assumed in MP2RAGE. We further observed a lower <i>f</i><sub>inv</sub> in white<br>
matter (WM) than in the rest of the cerebrum. Subsequent <i>T</i><sub>1</sub><br>
estimates differed by approximately 90 ms in WM and 230 ms in GM when assuming<br>
either <i>f</i><sub>inv</sub>=0.86 or <i>f</i><sub>inv</sub>=0.96.</p>}},
  author       = {{Olsson, Hampus and Helms, Gunther}},
  booktitle    = {{Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition}},
  issn         = {{1545-4428}},
  language     = {{eng}},
  month        = {{04}},
  publisher    = {{International Society for Magnetic Resonance in Medicine}},
  series       = {{Proc Intl Soc Magn Reson Med}},
  title        = {{Mapping the inversion efficiency (<i>f</i><sub>inv</sub>):
Comparison between adiabatic pulses for use in MP2RAGE-based <i>T</i><sub>1</sub>-mapping}},
  url          = {{https://index.mirasmart.com/ISMRM2022/PDFfiles/0372.html}},
  volume       = {{30}},
  year         = {{2022}},
}