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Intranasal Immunization of Mice with Group B Streptococcal Protein Rib and Cholera Toxin B Subunit Confers Protection against Lethal Infection.

Larsson, Charlotte U LU ; Holmgren, Jan ; Lindahl, Gunnar LU and Bergquist, Charlotta (2004) In Infection and Immunity 72(2). p.1184-1187
Abstract
Intranasal immunization of mice with Rib, a cell surface protein of group B streptococcus (GBS), conjugated to or simply coadministered with the recombinant cholera toxin B subunit, induces systemic immunoglobulin G (IgG) and local IgA antibody responses and confers protection against lethal GBS infection. These findings have implications for the development of a human GBS vaccine.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Infection and Immunity
volume
72
issue
2
pages
1184 - 1187
publisher
American Society for Microbiology
external identifiers
  • pmid:14742572
  • wos:000188766400072
  • scopus:0842282992
ISSN
1098-5522
DOI
10.1128/IAI.72.2.1184-1187.2004
language
English
LU publication?
yes
id
f2d86322-1ee9-4c99-9f28-1fadb3baf008 (old id 119962)
date added to LUP
2016-04-01 11:44:52
date last changed
2025-10-14 11:05:50
@article{f2d86322-1ee9-4c99-9f28-1fadb3baf008,
  abstract     = {{Intranasal immunization of mice with Rib, a cell surface protein of group B streptococcus (GBS), conjugated to or simply coadministered with the recombinant cholera toxin B subunit, induces systemic immunoglobulin G (IgG) and local IgA antibody responses and confers protection against lethal GBS infection. These findings have implications for the development of a human GBS vaccine.}},
  author       = {{Larsson, Charlotte U and Holmgren, Jan and Lindahl, Gunnar and Bergquist, Charlotta}},
  issn         = {{1098-5522}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{1184--1187}},
  publisher    = {{American Society for Microbiology}},
  series       = {{Infection and Immunity}},
  title        = {{Intranasal Immunization of Mice with Group B Streptococcal Protein Rib and Cholera Toxin B Subunit Confers Protection against Lethal Infection.}},
  url          = {{https://lup.lub.lu.se/search/files/2623460/623931.pdf}},
  doi          = {{10.1128/IAI.72.2.1184-1187.2004}},
  volume       = {{72}},
  year         = {{2004}},
}