Development of a thermal micro-biosensor fabricated on a silicon chip
(1992) In Sensors and Actuators B: Chemical 6(1-3). p.127-130- Abstract
In order to develop a sensitive, versatile and inexpensive portable instrument, a calorimetric micro-biosensor was designed and fabricated by etching part of the flow system into a silicon wafer. The utility of the device was tested using the enzymes, catalase and penicillinase. This sensor showed good reproducibility and linearity up to 100 mM. The system also showed higher sensitivity than the conventional enzyme thermistor (ET) when identical sample volumes (20 μl) were applied. Finally, future prospects in this field are discussed.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/f35a0aa8-46e1-4643-937a-a87fe25b6f39
- author
- Xie, Bin LU ; Danielsson, Bengt LU ; Norberg, Petronella ; Winquist, Fredrik and Lundström, Ingemar LU
- organization
- publishing date
- 1992-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Sensors and Actuators B: Chemical
- volume
- 6
- issue
- 1-3
- pages
- 4 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:0026459242
- ISSN
- 0925-4005
- DOI
- 10.1016/0925-4005(92)80043-W
- language
- English
- LU publication?
- yes
- id
- f35a0aa8-46e1-4643-937a-a87fe25b6f39
- date added to LUP
- 2021-10-27 16:12:08
- date last changed
- 2021-11-01 12:45:53
@article{f35a0aa8-46e1-4643-937a-a87fe25b6f39, abstract = {{<p>In order to develop a sensitive, versatile and inexpensive portable instrument, a calorimetric micro-biosensor was designed and fabricated by etching part of the flow system into a silicon wafer. The utility of the device was tested using the enzymes, catalase and penicillinase. This sensor showed good reproducibility and linearity up to 100 mM. The system also showed higher sensitivity than the conventional enzyme thermistor (ET) when identical sample volumes (20 μl) were applied. Finally, future prospects in this field are discussed.</p>}}, author = {{Xie, Bin and Danielsson, Bengt and Norberg, Petronella and Winquist, Fredrik and Lundström, Ingemar}}, issn = {{0925-4005}}, language = {{eng}}, number = {{1-3}}, pages = {{127--130}}, publisher = {{Elsevier}}, series = {{Sensors and Actuators B: Chemical}}, title = {{Development of a thermal micro-biosensor fabricated on a silicon chip}}, url = {{http://dx.doi.org/10.1016/0925-4005(92)80043-W}}, doi = {{10.1016/0925-4005(92)80043-W}}, volume = {{6}}, year = {{1992}}, }