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Development of a thermal micro-biosensor fabricated on a silicon chip

Xie, Bin LU ; Danielsson, Bengt LU ; Norberg, Petronella ; Winquist, Fredrik and Lundström, Ingemar LU (1992) In Sensors and Actuators B: Chemical 6(1-3). p.127-130
Abstract

In order to develop a sensitive, versatile and inexpensive portable instrument, a calorimetric micro-biosensor was designed and fabricated by etching part of the flow system into a silicon wafer. The utility of the device was tested using the enzymes, catalase and penicillinase. This sensor showed good reproducibility and linearity up to 100 mM. The system also showed higher sensitivity than the conventional enzyme thermistor (ET) when identical sample volumes (20 μl) were applied. Finally, future prospects in this field are discussed.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Sensors and Actuators B: Chemical
volume
6
issue
1-3
pages
4 pages
publisher
Elsevier
external identifiers
  • scopus:0026459242
ISSN
0925-4005
DOI
10.1016/0925-4005(92)80043-W
language
English
LU publication?
yes
id
f35a0aa8-46e1-4643-937a-a87fe25b6f39
date added to LUP
2021-10-27 16:12:08
date last changed
2021-11-01 12:45:53
@article{f35a0aa8-46e1-4643-937a-a87fe25b6f39,
  abstract     = {{<p>In order to develop a sensitive, versatile and inexpensive portable instrument, a calorimetric micro-biosensor was designed and fabricated by etching part of the flow system into a silicon wafer. The utility of the device was tested using the enzymes, catalase and penicillinase. This sensor showed good reproducibility and linearity up to 100 mM. The system also showed higher sensitivity than the conventional enzyme thermistor (ET) when identical sample volumes (20 μl) were applied. Finally, future prospects in this field are discussed.</p>}},
  author       = {{Xie, Bin and Danielsson, Bengt and Norberg, Petronella and Winquist, Fredrik and Lundström, Ingemar}},
  issn         = {{0925-4005}},
  language     = {{eng}},
  number       = {{1-3}},
  pages        = {{127--130}},
  publisher    = {{Elsevier}},
  series       = {{Sensors and Actuators B: Chemical}},
  title        = {{Development of a thermal micro-biosensor fabricated on a silicon chip}},
  url          = {{http://dx.doi.org/10.1016/0925-4005(92)80043-W}},
  doi          = {{10.1016/0925-4005(92)80043-W}},
  volume       = {{6}},
  year         = {{1992}},
}