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Enteric neuropathy can be induced by high fat diet in vivo and palmitic Acid exposure in vitro.

Voss, Ulrikke LU ; Sand, Elin LU ; Olde, Björn LU and Ekblad, Eva LU (2013) In PLoS ONE 8(12).
Abstract
Obese and/or diabetic patients have elevated levels of free fatty acids and increased susceptibility to gastrointestinal symptoms. Since the enteric nervous system is pivotal in regulating gastrointestinal functions alterations or neuropathy in the enteric neurons are suspected to occur in these conditions. Lipid induced intestinal changes, in particular on enteric neurons, were investigated in vitro and in vivo using primary cell culture and a high fat diet (HFD) mouse model.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
8
issue
12
article number
e81413
publisher
Public Library of Science (PLoS)
external identifiers
  • wos:000327947800046
  • pmid:24312551
  • scopus:84891817993
  • pmid:24312551
ISSN
1932-6203
DOI
10.1371/journal.pone.0081413
language
English
LU publication?
yes
id
f373542f-e75f-48db-8a2a-5adce3eb12df (old id 4225123)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24312551?dopt=Abstract
date added to LUP
2016-04-01 14:38:59
date last changed
2022-04-06 19:45:44
@article{f373542f-e75f-48db-8a2a-5adce3eb12df,
  abstract     = {{Obese and/or diabetic patients have elevated levels of free fatty acids and increased susceptibility to gastrointestinal symptoms. Since the enteric nervous system is pivotal in regulating gastrointestinal functions alterations or neuropathy in the enteric neurons are suspected to occur in these conditions. Lipid induced intestinal changes, in particular on enteric neurons, were investigated in vitro and in vivo using primary cell culture and a high fat diet (HFD) mouse model.}},
  author       = {{Voss, Ulrikke and Sand, Elin and Olde, Björn and Ekblad, Eva}},
  issn         = {{1932-6203}},
  language     = {{eng}},
  number       = {{12}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLoS ONE}},
  title        = {{Enteric neuropathy can be induced by high fat diet in vivo and palmitic Acid exposure in vitro.}},
  url          = {{https://lup.lub.lu.se/search/files/4085795/4438025.pdf}},
  doi          = {{10.1371/journal.pone.0081413}},
  volume       = {{8}},
  year         = {{2013}},
}