Enteric neuropathy can be induced by high fat diet in vivo and palmitic Acid exposure in vitro.
(2013) In PLoS ONE 8(12).- Abstract
- Obese and/or diabetic patients have elevated levels of free fatty acids and increased susceptibility to gastrointestinal symptoms. Since the enteric nervous system is pivotal in regulating gastrointestinal functions alterations or neuropathy in the enteric neurons are suspected to occur in these conditions. Lipid induced intestinal changes, in particular on enteric neurons, were investigated in vitro and in vivo using primary cell culture and a high fat diet (HFD) mouse model.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4225123
- author
- Voss, Ulrikke LU ; Sand, Elin LU ; Olde, Björn LU and Ekblad, Eva LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- PLoS ONE
- volume
- 8
- issue
- 12
- article number
- e81413
- publisher
- Public Library of Science (PLoS)
- external identifiers
-
- wos:000327947800046
- pmid:24312551
- scopus:84891817993
- pmid:24312551
- ISSN
- 1932-6203
- DOI
- 10.1371/journal.pone.0081413
- language
- English
- LU publication?
- yes
- id
- f373542f-e75f-48db-8a2a-5adce3eb12df (old id 4225123)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24312551?dopt=Abstract
- date added to LUP
- 2016-04-01 14:38:59
- date last changed
- 2022-04-06 19:45:44
@article{f373542f-e75f-48db-8a2a-5adce3eb12df, abstract = {{Obese and/or diabetic patients have elevated levels of free fatty acids and increased susceptibility to gastrointestinal symptoms. Since the enteric nervous system is pivotal in regulating gastrointestinal functions alterations or neuropathy in the enteric neurons are suspected to occur in these conditions. Lipid induced intestinal changes, in particular on enteric neurons, were investigated in vitro and in vivo using primary cell culture and a high fat diet (HFD) mouse model.}}, author = {{Voss, Ulrikke and Sand, Elin and Olde, Björn and Ekblad, Eva}}, issn = {{1932-6203}}, language = {{eng}}, number = {{12}}, publisher = {{Public Library of Science (PLoS)}}, series = {{PLoS ONE}}, title = {{Enteric neuropathy can be induced by high fat diet in vivo and palmitic Acid exposure in vitro.}}, url = {{https://lup.lub.lu.se/search/files/4085795/4438025.pdf}}, doi = {{10.1371/journal.pone.0081413}}, volume = {{8}}, year = {{2013}}, }