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Mortality risk comparing walking pace to handgrip strength and a healthy lifestyle : A UK Biobank study

Zaccardi, Francesco ; Franks, Paul W. LU ; Dudbridge, Frank ; Davies, Melanie J. ; Khunti, Kamlesh and Yates, Thomas (2019) In European Journal of Preventive Cardiology
Abstract

Aims: Brisk walking and a greater muscle strength have been associated with a longer life; whether these associations are influenced by other lifestyle behaviours, however, is less well known. 

Methods: Information on usual walking pace (self-defined as slow, steady/average, or brisk), dynamometer-assessed handgrip strength, lifestyle behaviours (physical activity, TV viewing, diet, alcohol intake, sleep and smoking) and body mass index was collected at baseline in 450,888 UK Biobank study participants. We estimated 10-year standardised survival for individual and combined lifestyle behaviours and body mass index across levels of walking pace and handgrip strength. 

Results: Over a median follow-up of 7.0 years, 3808 (1.6%)... (More)

Aims: Brisk walking and a greater muscle strength have been associated with a longer life; whether these associations are influenced by other lifestyle behaviours, however, is less well known. 

Methods: Information on usual walking pace (self-defined as slow, steady/average, or brisk), dynamometer-assessed handgrip strength, lifestyle behaviours (physical activity, TV viewing, diet, alcohol intake, sleep and smoking) and body mass index was collected at baseline in 450,888 UK Biobank study participants. We estimated 10-year standardised survival for individual and combined lifestyle behaviours and body mass index across levels of walking pace and handgrip strength. 

Results: Over a median follow-up of 7.0 years, 3808 (1.6%) deaths in women and 6783 (3.2%) in men occurred. Brisk walkers had a survival advantage over slow walkers, irrespective of the degree of engagement in other lifestyle behaviours, except for smoking. Estimated 10-year survival was higher in brisk walkers who otherwise engaged in an unhealthy lifestyle compared to slow walkers who engaged in an otherwise healthy lifestyle: 97.1% (95% confidence interval: 96.9–97.3) vs 95.0% (94.6–95.4) in women; 94.8% (94.7–95.0) vs 93.7% (93.3–94.2) in men. Body mass index modified the association between walking pace and survival in men, with the largest survival benefits of brisk walking observed in underweight participants. Compared to walking pace, for handgrip strength there was more overlap in 10-year survival across lifestyle behaviours. 

Conclusion: Except for smoking, brisk walkers with an otherwise unhealthy lifestyle have a lower mortality risk than slow walkers with an otherwise healthy lifestyle.

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Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
absolute risk, grip strength, lifestyle, mortality, smoking, Walking pace
in
European Journal of Preventive Cardiology
publisher
SAGE Publications
external identifiers
  • pmid:31711304
  • scopus:85075118742
ISSN
2047-4873
DOI
10.1177/2047487319885041
language
English
LU publication?
yes
id
f3c4531f-e156-4cfe-b535-63e5dd02937f
date added to LUP
2019-12-04 15:31:37
date last changed
2020-01-13 02:34:35
@article{f3c4531f-e156-4cfe-b535-63e5dd02937f,
  abstract     = {<p>Aims: Brisk walking and a greater muscle strength have been associated with a longer life; whether these associations are influenced by other lifestyle behaviours, however, is less well known. </p><p>Methods: Information on usual walking pace (self-defined as slow, steady/average, or brisk), dynamometer-assessed handgrip strength, lifestyle behaviours (physical activity, TV viewing, diet, alcohol intake, sleep and smoking) and body mass index was collected at baseline in 450,888 UK Biobank study participants. We estimated 10-year standardised survival for individual and combined lifestyle behaviours and body mass index across levels of walking pace and handgrip strength. </p><p>Results: Over a median follow-up of 7.0 years, 3808 (1.6%) deaths in women and 6783 (3.2%) in men occurred. Brisk walkers had a survival advantage over slow walkers, irrespective of the degree of engagement in other lifestyle behaviours, except for smoking. Estimated 10-year survival was higher in brisk walkers who otherwise engaged in an unhealthy lifestyle compared to slow walkers who engaged in an otherwise healthy lifestyle: 97.1% (95% confidence interval: 96.9–97.3) vs 95.0% (94.6–95.4) in women; 94.8% (94.7–95.0) vs 93.7% (93.3–94.2) in men. Body mass index modified the association between walking pace and survival in men, with the largest survival benefits of brisk walking observed in underweight participants. Compared to walking pace, for handgrip strength there was more overlap in 10-year survival across lifestyle behaviours. </p><p>Conclusion: Except for smoking, brisk walkers with an otherwise unhealthy lifestyle have a lower mortality risk than slow walkers with an otherwise healthy lifestyle.</p>},
  author       = {Zaccardi, Francesco and Franks, Paul W. and Dudbridge, Frank and Davies, Melanie J. and Khunti, Kamlesh and Yates, Thomas},
  issn         = {2047-4873},
  language     = {eng},
  month        = {11},
  publisher    = {SAGE Publications},
  series       = {European Journal of Preventive Cardiology},
  title        = {Mortality risk comparing walking pace to handgrip strength and a healthy lifestyle : A UK Biobank study},
  url          = {http://dx.doi.org/10.1177/2047487319885041},
  doi          = {10.1177/2047487319885041},
  year         = {2019},
}