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Improvement in diagnostic quality of structural and angiographic MRI of the brain using motion correction with interleaved, volumetric navigators

Andersen, Mads LU ; Björkman-Burtscher, Isabella M. LU ; Marsman, Anouk; Petersen, Esben Thade and Boer, Vincent Oltman (2019) In PLoS ONE 14(5).
Abstract

Introduction Subject movements lead to severe artifacts in magnetic resonance (MR) brain imaging. In this study we evaluate the diagnostic image quality in T1-weighted, T2-weighted, and timeof-flight angiographic MR sequences when using a flexible, navigator-based prospective motion correction system (iMOCO). Methods Five healthy volunteers were scanned during different movement scenarios with and without (+/-) iMOCO activated. An experienced neuroradiologist graded images for image quality criteria (grey-white-matter discrimination, basal ganglia, and small structure and vessel delineation), and general image quality on a four-grade scale. Results In scans with deliberate motion, there was a significant improvement in the image quality... (More)

Introduction Subject movements lead to severe artifacts in magnetic resonance (MR) brain imaging. In this study we evaluate the diagnostic image quality in T1-weighted, T2-weighted, and timeof-flight angiographic MR sequences when using a flexible, navigator-based prospective motion correction system (iMOCO). Methods Five healthy volunteers were scanned during different movement scenarios with and without (+/-) iMOCO activated. An experienced neuroradiologist graded images for image quality criteria (grey-white-matter discrimination, basal ganglia, and small structure and vessel delineation), and general image quality on a four-grade scale. Results In scans with deliberate motion, there was a significant improvement in the image quality with iMOCO compared to the scans without iMOCO in both general image impression (T1 p<0.01, T2 p<0.01, TOF p = 0.03) and in anatomical grading (T1 p<0.01, T2 p<0.01, TOF p = 0.01). Subjective image quality was considered non-diagnostic in 91% of the scans with motion -iMOCO, but only in 4% of the scans with motion +iMOCO. iMOCO performed best in the T1-weighted sequence and least well in the angiography sequence. iMOCO was not shown to have any negative effect on diagnostic image quality, as no significant difference in diagnostic quality was seen between scans -iMOCO and +iMOCO with no deliberate movement. Conclusion The evaluation showed that iMOCO enables substantial improvements in image quality in scans affected by subject movement, recovering important diagnostic information in an otherwise unusable scan.

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published
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in
PLoS ONE
volume
14
issue
5
publisher
Public Library of Science
external identifiers
  • scopus:85066064830
ISSN
1932-6203
DOI
10.1371/journal.pone.0217145
language
English
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yes
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f441db5d-1bab-4178-98e4-180dc5e7bf0b
date added to LUP
2019-06-11 14:54:58
date last changed
2019-07-07 05:10:55
@article{f441db5d-1bab-4178-98e4-180dc5e7bf0b,
  abstract     = {<p>Introduction Subject movements lead to severe artifacts in magnetic resonance (MR) brain imaging. In this study we evaluate the diagnostic image quality in T1-weighted, T2-weighted, and timeof-flight angiographic MR sequences when using a flexible, navigator-based prospective motion correction system (iMOCO). Methods Five healthy volunteers were scanned during different movement scenarios with and without (+/-) iMOCO activated. An experienced neuroradiologist graded images for image quality criteria (grey-white-matter discrimination, basal ganglia, and small structure and vessel delineation), and general image quality on a four-grade scale. Results In scans with deliberate motion, there was a significant improvement in the image quality with iMOCO compared to the scans without iMOCO in both general image impression (T1 p&lt;0.01, T2 p&lt;0.01, TOF p = 0.03) and in anatomical grading (T1 p&lt;0.01, T2 p&lt;0.01, TOF p = 0.01). Subjective image quality was considered non-diagnostic in 91% of the scans with motion -iMOCO, but only in 4% of the scans with motion +iMOCO. iMOCO performed best in the T1-weighted sequence and least well in the angiography sequence. iMOCO was not shown to have any negative effect on diagnostic image quality, as no significant difference in diagnostic quality was seen between scans -iMOCO and +iMOCO with no deliberate movement. Conclusion The evaluation showed that iMOCO enables substantial improvements in image quality in scans affected by subject movement, recovering important diagnostic information in an otherwise unusable scan.</p>},
  articleno    = {e0217145},
  author       = {Andersen, Mads and Björkman-Burtscher, Isabella M. and Marsman, Anouk and Petersen, Esben Thade and Boer, Vincent Oltman},
  issn         = {1932-6203},
  language     = {eng},
  month        = {05},
  number       = {5},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Improvement in diagnostic quality of structural and angiographic MRI of the brain using motion correction with interleaved, volumetric navigators},
  url          = {http://dx.doi.org/10.1371/journal.pone.0217145},
  volume       = {14},
  year         = {2019},
}