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Diabetes mellitus, high BMI and low education level predict sudden cardiac death within 24 hours of incident myocardial infarction

Andersson, Jonas LU ; Wennberg, Patrik; Lundblad, Dan; Escher, Stefan A. and Jansson, Jan Håkan (2016) In European Journal of Preventive Cardiology 23(17). p.1814-1820
Abstract

Background More than half of cardiovascular mortality occurs outside the hospital, mainly due to consistently low survival rates from out-of-hospital cardiac arrest. Methods This is a prospective, nested, case-control study derived from the Västerbotten Intervention Programme and the World Health Organization's Multinational Monitoring of Trends and Determinants in Cardiovascular Disease study in northern Sweden (1986-2006). To determine predictors for sudden cardiac death risk factors for cardiovascular disease were compared between incident myocardial infarction with sudden cardiac death (n = 363) and survivors of incident myocardial infarction (n = 1998) using multivariate logistic regression analysis. Results Diabetes had the... (More)

Background More than half of cardiovascular mortality occurs outside the hospital, mainly due to consistently low survival rates from out-of-hospital cardiac arrest. Methods This is a prospective, nested, case-control study derived from the Västerbotten Intervention Programme and the World Health Organization's Multinational Monitoring of Trends and Determinants in Cardiovascular Disease study in northern Sweden (1986-2006). To determine predictors for sudden cardiac death risk factors for cardiovascular disease were compared between incident myocardial infarction with sudden cardiac death (n = 363) and survivors of incident myocardial infarction (n = 1998) using multivariate logistic regression analysis. Results Diabetes had the strongest association with sudden cardiac death out of all evaluated risk factors (odds ratio (OR) 1.83, 95% confidence interval (CI) 1.30-2.59), followed by low education (OR 1.55, 95% CI 1.19-2.01), high body mass index (OR 1.05, 95% CI 1.02-1.08) and male sex (OR 1.42, 95% CI 1.001-2.01). Conclusions The pattern of risk factors for incident myocardial infarction is different among survivors and those who die within 24 hours. The risk factors that contribute the most to death within 24 hours are diabetes mellitus, high body mass index and low education level, and can be addressed at both the public health level and by general practitioners.

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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
epidemiology, myocardial infarction, prevention, prognosis, risk factors, Sudden cardiac death
in
European Journal of Preventive Cardiology
volume
23
issue
17
pages
7 pages
publisher
SAGE Publications Inc.
external identifiers
  • scopus:84993982845
  • wos:000387017100003
ISSN
2047-4873
DOI
10.1177/2047487316659574
language
English
LU publication?
no
id
f4b35adf-b343-4c85-a09b-69730f1a8f5c
date added to LUP
2016-12-08 15:07:45
date last changed
2017-03-19 04:38:10
@article{f4b35adf-b343-4c85-a09b-69730f1a8f5c,
  abstract     = {<p>Background More than half of cardiovascular mortality occurs outside the hospital, mainly due to consistently low survival rates from out-of-hospital cardiac arrest. Methods This is a prospective, nested, case-control study derived from the Västerbotten Intervention Programme and the World Health Organization's Multinational Monitoring of Trends and Determinants in Cardiovascular Disease study in northern Sweden (1986-2006). To determine predictors for sudden cardiac death risk factors for cardiovascular disease were compared between incident myocardial infarction with sudden cardiac death (n = 363) and survivors of incident myocardial infarction (n = 1998) using multivariate logistic regression analysis. Results Diabetes had the strongest association with sudden cardiac death out of all evaluated risk factors (odds ratio (OR) 1.83, 95% confidence interval (CI) 1.30-2.59), followed by low education (OR 1.55, 95% CI 1.19-2.01), high body mass index (OR 1.05, 95% CI 1.02-1.08) and male sex (OR 1.42, 95% CI 1.001-2.01). Conclusions The pattern of risk factors for incident myocardial infarction is different among survivors and those who die within 24 hours. The risk factors that contribute the most to death within 24 hours are diabetes mellitus, high body mass index and low education level, and can be addressed at both the public health level and by general practitioners.</p>},
  author       = {Andersson, Jonas and Wennberg, Patrik and Lundblad, Dan and Escher, Stefan A. and Jansson, Jan Håkan},
  issn         = {2047-4873},
  keyword      = {epidemiology,myocardial infarction,prevention,prognosis,risk factors,Sudden cardiac death},
  language     = {eng},
  month        = {11},
  number       = {17},
  pages        = {1814--1820},
  publisher    = {SAGE Publications Inc.},
  series       = {European Journal of Preventive Cardiology},
  title        = {Diabetes mellitus, high BMI and low education level predict sudden cardiac death within 24 hours of incident myocardial infarction},
  url          = {http://dx.doi.org/10.1177/2047487316659574},
  volume       = {23},
  year         = {2016},
}