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Contact allergy to haptens in the Swedish baseline series : Results from the Swedish Patch Test Register (2010 to 2017)

Andernord, Daniel ; Bruze, Magnus LU ; Bryngelsson, Ing Liss ; Bråred Christensson, Johanna ; Glas, Bo ; Hagvall, Lina LU ; Isaksson, Marléne LU ; Matura, Mihály ; Nyman, Gunnar and Stenberg, Berndt , et al. (2022) In Contact Dermatitis 86(3). p.175-188
Abstract

Background: Allergic contact dermatitis has considerable public health impact and causative haptens vary over time. Objectives: To report the prevalence of contact allergy to allergens in the Swedish baseline series 2010 to 2017, as registered in the Swedish Patch Test Register. Methods: Results and demographic information for patients tested with the Swedish baseline series in 2010 to 2017 were analysed. Results: Data for 21 663 individuals (females 69%) were included. Females had significantly more positive patch tests (54% vs 40%). The reaction prevalence rates were highest for nickel sulfate (20.7%), fragrance mix I (7.1%), Myroxylon pereirae (6.9%), potassium dichromate (6.9%), cobalt chloride (6.8%),... (More)

Background: Allergic contact dermatitis has considerable public health impact and causative haptens vary over time. Objectives: To report the prevalence of contact allergy to allergens in the Swedish baseline series 2010 to 2017, as registered in the Swedish Patch Test Register. Methods: Results and demographic information for patients tested with the Swedish baseline series in 2010 to 2017 were analysed. Results: Data for 21 663 individuals (females 69%) were included. Females had significantly more positive patch tests (54% vs 40%). The reaction prevalence rates were highest for nickel sulfate (20.7%), fragrance mix I (7.1%), Myroxylon pereirae (6.9%), potassium dichromate (6.9%), cobalt chloride (6.8%), methylchloroisothiazolinone/methylisothiazolinone (MCI/MI; 6.4%), MI (3.7%), colophonium (3.5%), fragrance mix II (3.2%), and formaldehyde (3.2%). Myroxylon pereirae reaction prevalence increased from 5% in 2010 to 9% in 2017 and that for methyldibromo glutaronitrile from 3.1% to 4.6%. MCI/MI and MI reactions decreased in prevalence after 2014. Nickel reaction prevalence decreased among females aged 10 to 19 years. Conclusions: Nickel remains the most common sensitizing agent, with reaction prevalence decreasing among females younger than 20 years. The changes in MCI/MI and MI reaction prevalence mirrored those in Europe. The register can reveal changes in contact allergy prevalence over time among patients patch tested in Sweden.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
contact allergy, contact dermatitis, eczema, fragrance, methylchloroisothiazolinone, methylisothiazolinone, nickel, patch test, preservative, Sweden, Swedish baseline series
in
Contact Dermatitis
volume
86
issue
3
pages
175 - 188
publisher
Wiley-Blackwell
external identifiers
  • scopus:85125012294
  • pmid:34704261
  • scopus:85118798755
ISSN
0105-1873
DOI
10.1111/cod.13996
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
id
f4dab1b5-7cf1-486f-900b-d99cbec67f40
date added to LUP
2021-12-02 15:14:47
date last changed
2022-09-17 19:46:41
@article{f4dab1b5-7cf1-486f-900b-d99cbec67f40,
  abstract     = {{<p>Background: Allergic contact dermatitis has considerable public health impact and causative haptens vary over time. Objectives: To report the prevalence of contact allergy to allergens in the Swedish baseline series 2010 to 2017, as registered in the Swedish Patch Test Register. Methods: Results and demographic information for patients tested with the Swedish baseline series in 2010 to 2017 were analysed. Results: Data for 21 663 individuals (females 69%) were included. Females had significantly more positive patch tests (54% vs 40%). The reaction prevalence rates were highest for nickel sulfate (20.7%), fragrance mix I (7.1%), Myroxylon pereirae (6.9%), potassium dichromate (6.9%), cobalt chloride (6.8%), methylchloroisothiazolinone/methylisothiazolinone (MCI/MI; 6.4%), MI (3.7%), colophonium (3.5%), fragrance mix II (3.2%), and formaldehyde (3.2%). Myroxylon pereirae reaction prevalence increased from 5% in 2010 to 9% in 2017 and that for methyldibromo glutaronitrile from 3.1% to 4.6%. MCI/MI and MI reactions decreased in prevalence after 2014. Nickel reaction prevalence decreased among females aged 10 to 19 years. Conclusions: Nickel remains the most common sensitizing agent, with reaction prevalence decreasing among females younger than 20 years. The changes in MCI/MI and MI reaction prevalence mirrored those in Europe. The register can reveal changes in contact allergy prevalence over time among patients patch tested in Sweden.</p>}},
  author       = {{Andernord, Daniel and Bruze, Magnus and Bryngelsson, Ing Liss and Bråred Christensson, Johanna and Glas, Bo and Hagvall, Lina and Isaksson, Marléne and Matura, Mihály and Nyman, Gunnar and Stenberg, Berndt and Svedman, Cecilia and Lindberg, Magnus}},
  issn         = {{0105-1873}},
  keywords     = {{contact allergy; contact dermatitis; eczema; fragrance; methylchloroisothiazolinone; methylisothiazolinone; nickel; patch test; preservative; Sweden; Swedish baseline series}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{175--188}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Contact Dermatitis}},
  title        = {{Contact allergy to haptens in the Swedish baseline series : Results from the Swedish Patch Test Register (2010 to 2017)}},
  url          = {{http://dx.doi.org/10.1111/cod.13996}},
  doi          = {{10.1111/cod.13996}},
  volume       = {{86}},
  year         = {{2022}},
}