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Serum beta-hexosaminidase in diabetes mellitus with reference to the type of treatment

Agardh, Carl-David LU ; Hultberg, Björn LU and Thoren, S (1982) In Acta Medica Scandinavica 212(1-2). p.39-41
Abstract
A significantly increased serum level of beta-hexosaminidase was found in an unselected group of 85 diabetics. When the patients were divided into three groups according to type of treatment, increased enzyme levels were found only in patients treated with oral hypoglycemic agents or diet while insulin-treated patients had normal serum levels of beta-hexosaminidase. There was a positive correlation between beta-hexosaminidase and blood glucose concentration for the entire patient series. When grouped according to treatment, a positive correlation was found only in the insulin-treated group despite its normal serum activity of beta-hexosaminidase. Serum beta-hexosaminidase of patients with retinopathy did not differ from the mean value of... (More)
A significantly increased serum level of beta-hexosaminidase was found in an unselected group of 85 diabetics. When the patients were divided into three groups according to type of treatment, increased enzyme levels were found only in patients treated with oral hypoglycemic agents or diet while insulin-treated patients had normal serum levels of beta-hexosaminidase. There was a positive correlation between beta-hexosaminidase and blood glucose concentration for the entire patient series. When grouped according to treatment, a positive correlation was found only in the insulin-treated group despite its normal serum activity of beta-hexosaminidase. Serum beta-hexosaminidase of patients with retinopathy did not differ from the mean value of their group. It is concluded that the activity of beta-hexosaminidase in diabetics can produce different results depending on the type of patients under study. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Medica Scandinavica
volume
212
issue
1-2
pages
39 - 41
publisher
Wiley-Blackwell
external identifiers
  • pmid:6214927
  • scopus:0019981244
ISSN
0001-6101
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Clinical Chemistry and Pharmacology (013250300), Unit on Vascular Diabetic Complications (013241510)
id
f55b260b-848d-4adb-aacd-2f4ec0117173 (old id 1102949)
date added to LUP
2016-04-01 16:48:44
date last changed
2021-01-03 03:42:57
@article{f55b260b-848d-4adb-aacd-2f4ec0117173,
  abstract     = {{A significantly increased serum level of beta-hexosaminidase was found in an unselected group of 85 diabetics. When the patients were divided into three groups according to type of treatment, increased enzyme levels were found only in patients treated with oral hypoglycemic agents or diet while insulin-treated patients had normal serum levels of beta-hexosaminidase. There was a positive correlation between beta-hexosaminidase and blood glucose concentration for the entire patient series. When grouped according to treatment, a positive correlation was found only in the insulin-treated group despite its normal serum activity of beta-hexosaminidase. Serum beta-hexosaminidase of patients with retinopathy did not differ from the mean value of their group. It is concluded that the activity of beta-hexosaminidase in diabetics can produce different results depending on the type of patients under study.}},
  author       = {{Agardh, Carl-David and Hultberg, Björn and Thoren, S}},
  issn         = {{0001-6101}},
  language     = {{eng}},
  number       = {{1-2}},
  pages        = {{39--41}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Medica Scandinavica}},
  title        = {{Serum beta-hexosaminidase in diabetes mellitus with reference to the type of treatment}},
  volume       = {{212}},
  year         = {{1982}},
}