Advanced

Outcome of a psychosocial health promotion intervention aimed at improving physical health and reducing alcohol use in patients with schizophrenia and psychotic disorders (MINT)

Westman, Jeanette; Eberhard, Jonas LU ; Gaughran, Fiona P.; Lundin, Lennart; Stenmark, Richard LU ; Edman, Gunnar; Eriksson, Sven V.; Jedenius, Erik; Rydell, Pia and Overgaard, Karin, et al. (2019) In Schizophrenia Research 208. p.138-144
Abstract

Background: Life expectancy is reduced by 19 years in men and 17 in women with psychosis in Sweden, largely due to cardiovascular disease. Aim: Assess whether a psychosocial health promotion intervention improves cardiometabolic risk factors, quality of life, and severity of illness in patients with psychotic disorders more than treatment as usual. Methods: A pragmatic intervention trial testing a manual-based multi-component health promotion intervention targeting patients with psychosis. The Swedish intervention was adapted from IMPaCT therapy, a health-promotion program based on motivational interviewing and cognitive behavioral therapy, designed to be incorporated into routine care. The intervention group consisted of 119 patients... (More)

Background: Life expectancy is reduced by 19 years in men and 17 in women with psychosis in Sweden, largely due to cardiovascular disease. Aim: Assess whether a psychosocial health promotion intervention improves cardiometabolic risk factors, quality of life, and severity of illness in patients with psychotic disorders more than treatment as usual. Methods: A pragmatic intervention trial testing a manual-based multi-component health promotion intervention targeting patients with psychosis. The Swedish intervention was adapted from IMPaCT therapy, a health-promotion program based on motivational interviewing and cognitive behavioral therapy, designed to be incorporated into routine care. The intervention group consisted of 119 patients and the control group of 570 patients from specialized psychosis departments. Outcome variables were assessed 6 months before intervention during the run-in period, again at the start of intervention, and 12 months after the intervention began. The control group received treatment as usual. Results: The intervention had no significant effect on any of the outcome variables. However, BMI, waist circumference, systolic BP, heart rate, HbA1c, general health, and Clinical Global Impressions Scale score improved significantly during the run-in period before the start of the active intervention (observer effect). The multi-component design meant that treatment effects could only be calculated for the intervention as a whole. Conclusion: The results of the intervention are similar to those of the U.K. IMPaCT study, in which the modular health-promotion intervention had little effect on cardiovascular risk indicators. However, in the current study, the run-in period had a positive effect on cardiometabolic risk factors.

(Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Cardiovascular risk factors, Lifestyle intervention, Mental health, Psychiatric care, Psychosis, Run-in period
in
Schizophrenia Research
volume
208
pages
138 - 144
publisher
Elsevier
external identifiers
  • scopus:85064003950
ISSN
0920-9964
DOI
10.1016/j.schres.2019.03.026
language
English
LU publication?
yes
id
f5fba4ae-71f7-4286-aa79-b34cc1f376fa
date added to LUP
2019-05-09 12:39:54
date last changed
2019-07-01 13:37:23
@article{f5fba4ae-71f7-4286-aa79-b34cc1f376fa,
  abstract     = {<p>Background: Life expectancy is reduced by 19 years in men and 17 in women with psychosis in Sweden, largely due to cardiovascular disease. Aim: Assess whether a psychosocial health promotion intervention improves cardiometabolic risk factors, quality of life, and severity of illness in patients with psychotic disorders more than treatment as usual. Methods: A pragmatic intervention trial testing a manual-based multi-component health promotion intervention targeting patients with psychosis. The Swedish intervention was adapted from IMPaCT therapy, a health-promotion program based on motivational interviewing and cognitive behavioral therapy, designed to be incorporated into routine care. The intervention group consisted of 119 patients and the control group of 570 patients from specialized psychosis departments. Outcome variables were assessed 6 months before intervention during the run-in period, again at the start of intervention, and 12 months after the intervention began. The control group received treatment as usual. Results: The intervention had no significant effect on any of the outcome variables. However, BMI, waist circumference, systolic BP, heart rate, HbA1c, general health, and Clinical Global Impressions Scale score improved significantly during the run-in period before the start of the active intervention (observer effect). The multi-component design meant that treatment effects could only be calculated for the intervention as a whole. Conclusion: The results of the intervention are similar to those of the U.K. IMPaCT study, in which the modular health-promotion intervention had little effect on cardiovascular risk indicators. However, in the current study, the run-in period had a positive effect on cardiometabolic risk factors.</p>},
  author       = {Westman, Jeanette and Eberhard, Jonas and Gaughran, Fiona P. and Lundin, Lennart and Stenmark, Richard and Edman, Gunnar and Eriksson, Sven V. and Jedenius, Erik and Rydell, Pia and Overgaard, Karin and Abrams, Daniel and Greenwood, Kathryn E. and Smith, Shubulade and Ismail, Khalida and Murray, Robin and Ösby, Urban},
  issn         = {0920-9964},
  keyword      = {Cardiovascular risk factors,Lifestyle intervention,Mental health,Psychiatric care,Psychosis,Run-in period},
  language     = {eng},
  pages        = {138--144},
  publisher    = {Elsevier},
  series       = {Schizophrenia Research},
  title        = {Outcome of a psychosocial health promotion intervention aimed at improving physical health and reducing alcohol use in patients with schizophrenia and psychotic disorders (MINT)},
  url          = {http://dx.doi.org/10.1016/j.schres.2019.03.026},
  volume       = {208},
  year         = {2019},
}