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Mesencephalic clefts with associated eye movement disorders

Lagrèze, Wolf Dietrich A. ; Warner, Judith E.A. ; Zamani, Amir A. ; Gouras, Gunnar K. LU orcid ; Koralnik, Igor J. and Bienfang, Don C. (1996) In Archives of Ophthalmology 114(4). p.429-432
Abstract

Objective: To describe two patients with mesencephalic midline clefts and associated eye movement disorders. Design: Case reports. Results: The first patient developed bilateral internuclear ophthalmoplegia with exotropia, reduced convergence, right ptosis, right fourth-nerve palsy, and right elevator palsy several years after meningitis with hydrocephalus. The second patient had bilateral internuclear ophthalmoplegia with exotropia, reduced convergence, bilateral ptosis, limited upward gaze, and right hypertropia since childhood. In both patients, magnetic resonance imaging showed a midline cleft extending from the cerebral aqueduct into the midbrain. Conclusion: It is likely that the clefts affected the oculomotor nuclei and medial... (More)

Objective: To describe two patients with mesencephalic midline clefts and associated eye movement disorders. Design: Case reports. Results: The first patient developed bilateral internuclear ophthalmoplegia with exotropia, reduced convergence, right ptosis, right fourth-nerve palsy, and right elevator palsy several years after meningitis with hydrocephalus. The second patient had bilateral internuclear ophthalmoplegia with exotropia, reduced convergence, bilateral ptosis, limited upward gaze, and right hypertropia since childhood. In both patients, magnetic resonance imaging showed a midline cleft extending from the cerebral aqueduct into the midbrain. Conclusion: It is likely that the clefts affected the oculomotor nuclei and medial longitudinal fasciculi, accounting for the eye movement disorders.

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author
; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Archives of Ophthalmology
volume
114
issue
4
pages
429 - 432
publisher
American Medical Association
external identifiers
  • scopus:0029981683
  • pmid:8602780
ISSN
0003-9950
DOI
10.1001/archopht.1996.01100130425012
language
English
LU publication?
no
id
f6bafb28-a2ba-40ea-9ade-677573b2085e
date added to LUP
2020-02-20 14:44:48
date last changed
2024-06-27 14:38:52
@article{f6bafb28-a2ba-40ea-9ade-677573b2085e,
  abstract     = {{<p>Objective: To describe two patients with mesencephalic midline clefts and associated eye movement disorders. Design: Case reports. Results: The first patient developed bilateral internuclear ophthalmoplegia with exotropia, reduced convergence, right ptosis, right fourth-nerve palsy, and right elevator palsy several years after meningitis with hydrocephalus. The second patient had bilateral internuclear ophthalmoplegia with exotropia, reduced convergence, bilateral ptosis, limited upward gaze, and right hypertropia since childhood. In both patients, magnetic resonance imaging showed a midline cleft extending from the cerebral aqueduct into the midbrain. Conclusion: It is likely that the clefts affected the oculomotor nuclei and medial longitudinal fasciculi, accounting for the eye movement disorders.</p>}},
  author       = {{Lagrèze, Wolf Dietrich A. and Warner, Judith E.A. and Zamani, Amir A. and Gouras, Gunnar K. and Koralnik, Igor J. and Bienfang, Don C.}},
  issn         = {{0003-9950}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{429--432}},
  publisher    = {{American Medical Association}},
  series       = {{Archives of Ophthalmology}},
  title        = {{Mesencephalic clefts with associated eye movement disorders}},
  url          = {{http://dx.doi.org/10.1001/archopht.1996.01100130425012}},
  doi          = {{10.1001/archopht.1996.01100130425012}},
  volume       = {{114}},
  year         = {{1996}},
}