Monkeypox : A Comprehensive Review
(2022) In Viruses 14(10).- Abstract
The 2022 multi-country monkeypox outbreak in humans has brought new public health adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease has spread to 104 countries throughout six continents of the world, with the highest burden in North America and Europe. The etiologic agent, monkeypox virus (MPXV), has been known since 1959 after isolation from infected monkeys, and virulence among humans has been reported since the 1970s, mainly in endemic countries in West and Central Africa. However, the disease has re-emerged in 2022 at an unprecedented pace, with particular concern on its human-to-human transmissibility and community spread in non-endemic regions. As a mitigation effort, healthcare workers,... (More)
The 2022 multi-country monkeypox outbreak in humans has brought new public health adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease has spread to 104 countries throughout six continents of the world, with the highest burden in North America and Europe. The etiologic agent, monkeypox virus (MPXV), has been known since 1959 after isolation from infected monkeys, and virulence among humans has been reported since the 1970s, mainly in endemic countries in West and Central Africa. However, the disease has re-emerged in 2022 at an unprecedented pace, with particular concern on its human-to-human transmissibility and community spread in non-endemic regions. As a mitigation effort, healthcare workers, public health policymakers, and the general public worldwide need to be well-informed on this relatively neglected viral disease. Here, we provide a comprehensive and up-to-date overview of monkeypox, including the following aspects: epidemiology, etiology, pathogenesis, clinical features, diagnosis, and management. In addition, the current review discusses the preventive and control measures, the latest vaccine developments, and the future research areas in this re-emerging viral disease that was declared as a public health emergency of international concern.
(Less)
- author
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- emergency, emerging viral infectious diseases, epidemic, international concern, prevention, public health, vaccination, zoonosis
- in
- Viruses
- volume
- 14
- issue
- 10
- article number
- 2155
- publisher
- MDPI AG
- external identifiers
-
- pmid:36298710
- scopus:85140634842
- ISSN
- 1999-4915
- DOI
- 10.3390/v14102155
- language
- English
- LU publication?
- yes
- id
- f72d476d-54ec-434a-a9d7-14b9800d3331
- date added to LUP
- 2022-12-14 11:48:11
- date last changed
- 2025-04-16 02:32:57
@article{f72d476d-54ec-434a-a9d7-14b9800d3331,
abstract = {{<p>The 2022 multi-country monkeypox outbreak in humans has brought new public health adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease has spread to 104 countries throughout six continents of the world, with the highest burden in North America and Europe. The etiologic agent, monkeypox virus (MPXV), has been known since 1959 after isolation from infected monkeys, and virulence among humans has been reported since the 1970s, mainly in endemic countries in West and Central Africa. However, the disease has re-emerged in 2022 at an unprecedented pace, with particular concern on its human-to-human transmissibility and community spread in non-endemic regions. As a mitigation effort, healthcare workers, public health policymakers, and the general public worldwide need to be well-informed on this relatively neglected viral disease. Here, we provide a comprehensive and up-to-date overview of monkeypox, including the following aspects: epidemiology, etiology, pathogenesis, clinical features, diagnosis, and management. In addition, the current review discusses the preventive and control measures, the latest vaccine developments, and the future research areas in this re-emerging viral disease that was declared as a public health emergency of international concern.</p>}},
author = {{Harapan, Harapan and Ophinni, Youdiil and Megawati, Dewi and Frediansyah, Andri and Mamada, Sukamto S. and Salampe, Mirnawati and Bin Emran, Talha and Winardi, Wira and Fathima, Raisha and Sirinam, Salin and Sittikul, Pichamon and Stoian, Ana M. and Nainu, Firzan and Sallam, Malik}},
issn = {{1999-4915}},
keywords = {{emergency; emerging viral infectious diseases; epidemic; international concern; prevention; public health; vaccination; zoonosis}},
language = {{eng}},
number = {{10}},
publisher = {{MDPI AG}},
series = {{Viruses}},
title = {{Monkeypox : A Comprehensive Review}},
url = {{http://dx.doi.org/10.3390/v14102155}},
doi = {{10.3390/v14102155}},
volume = {{14}},
year = {{2022}},
}