Interaction between the labile binding site of human C4 and methylamine
(1981) In Scandinavian Journal of Immunology 13(2). p.199-203- Abstract
- Human complement component C4 was irreversibly inactivated by low concentrations of methylamine at slightly alkaline pH. The inactivated C4 molecules lost the ability to bind to EAC1 cells but retained th capacity to participate in the formation of classical pathway C3 convertase in the fluid phase. 14C-methylamine was incorporated into the alpha-chain at a ratio of 1 mol methylamine per mol C4.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3965006
- author
- Lundwall, Åke LU ; Malmheden, I. ; Hellman, U. and Sjoquist, J.
- publishing date
- 1981
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Humans, Polyacrylamide Gel, Electrophoresis, Complement C4/*antagonists & inhibitors, Complement Inactivator Proteins/pharmacology, Hydrogen-Ion Concentration, Methylamines/*pharmacology, Receptors, Complement/*drug effects, Research Support, Non-U.S. Gov't
- in
- Scandinavian Journal of Immunology
- volume
- 13
- issue
- 2
- pages
- 199 - 203
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0019464204
- ISSN
- 0300-9475
- language
- English
- LU publication?
- no
- additional info
- 2
- id
- f77929d1-09f5-462b-a84c-dab567c90fb4 (old id 3965006)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7233091
- date added to LUP
- 2016-04-04 12:57:46
- date last changed
- 2021-01-03 03:59:30
@article{f77929d1-09f5-462b-a84c-dab567c90fb4, abstract = {{Human complement component C4 was irreversibly inactivated by low concentrations of methylamine at slightly alkaline pH. The inactivated C4 molecules lost the ability to bind to EAC1 cells but retained th capacity to participate in the formation of classical pathway C3 convertase in the fluid phase. 14C-methylamine was incorporated into the alpha-chain at a ratio of 1 mol methylamine per mol C4.}}, author = {{Lundwall, Åke and Malmheden, I. and Hellman, U. and Sjoquist, J.}}, issn = {{0300-9475}}, keywords = {{Humans; Polyacrylamide Gel; Electrophoresis; Complement C4/*antagonists & inhibitors; Complement Inactivator Proteins/pharmacology; Hydrogen-Ion Concentration; Methylamines/*pharmacology; Receptors; Complement/*drug effects; Research Support; Non-U.S. Gov't}}, language = {{eng}}, number = {{2}}, pages = {{199--203}}, publisher = {{Wiley-Blackwell}}, series = {{Scandinavian Journal of Immunology}}, title = {{Interaction between the labile binding site of human C4 and methylamine}}, url = {{http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7233091}}, volume = {{13}}, year = {{1981}}, }