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Hip prosthetic loosening and periprosthetic osteolysis : A commentary

Mjöberg, Bengt LU orcid (2022) In World journal of orthopedics 13(6). p.574-577
Abstract

Prosthetic loosening and periprosthetic osteolysis have been debated for decades, both in terms of the timing and nature of the triggering events. The hypothesis of wear-particle-induced loosening states that wear particles cause a foreign-body response leading to periprosthetic osteolysis and ultimately to late prosthetic loosening, i.e., that the osteolysis precedes the loosening. The theory of early loosening, on the other hand, postulates that the loosening is already initiated during or shortly after surgery, i.e., that the osteolysis is secondary to the loosening. This commentary focuses on the causal relationship between prosthetic loosening and periprosthetic osteolysis.

Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Alarmins, Bone resorption, Hip prosthesis, Osteoclasts, Prosthesis failure, Radiostereometric analysis
in
World journal of orthopedics
volume
13
issue
6
pages
574 - 577
publisher
Baishideng Publishing Group
external identifiers
  • pmid:35949708
  • scopus:85132760766
ISSN
2218-5836
DOI
10.5312/wjo.v13.i6.574
language
English
LU publication?
yes
id
f7ce6864-45f6-482d-a1b5-ae0caf0778d2
date added to LUP
2022-08-24 16:00:11
date last changed
2024-03-17 10:45:11
@article{f7ce6864-45f6-482d-a1b5-ae0caf0778d2,
  abstract     = {{<p>Prosthetic loosening and periprosthetic osteolysis have been debated for decades, both in terms of the timing and nature of the triggering events. The hypothesis of wear-particle-induced loosening states that wear particles cause a foreign-body response leading to periprosthetic osteolysis and ultimately to late prosthetic loosening, i.e., that the osteolysis precedes the loosening. The theory of early loosening, on the other hand, postulates that the loosening is already initiated during or shortly after surgery, i.e., that the osteolysis is secondary to the loosening. This commentary focuses on the causal relationship between prosthetic loosening and periprosthetic osteolysis.</p>}},
  author       = {{Mjöberg, Bengt}},
  issn         = {{2218-5836}},
  keywords     = {{Alarmins; Bone resorption; Hip prosthesis; Osteoclasts; Prosthesis failure; Radiostereometric analysis}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{6}},
  pages        = {{574--577}},
  publisher    = {{Baishideng Publishing Group}},
  series       = {{World journal of orthopedics}},
  title        = {{Hip prosthetic loosening and periprosthetic osteolysis : A commentary}},
  url          = {{http://dx.doi.org/10.5312/wjo.v13.i6.574}},
  doi          = {{10.5312/wjo.v13.i6.574}},
  volume       = {{13}},
  year         = {{2022}},
}