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Abrupt decreases in infectivity of SARS-CoV-2 in aerosols

Löndahl, Jakob LU orcid and Alsved, Malin LU orcid (2022) In Proceedings of the National Academy of Sciences of the United States of America 119(29).
Abstract
A respiratory virus emitted in an aerosol particle will experience a tough journey with many obstacles before finding a new host where it can cause an infection (Fig. 1). By every second, its chances to replicate decrease due to removal by building ventilation, deposition on surfaces, or loss in infectivity. Thus, the transport of infectious viruses from the exhaled breath of one person to the inhaled air of another typically occurs within a few minutes. During this short time, the aerosol will undergo several transformations because of changing environmental conditions. Nevertheless, due to methodological challenges, we still have a remarkably limited understanding of the relationships between environmental factors and survival of... (More)
A respiratory virus emitted in an aerosol particle will experience a tough journey with many obstacles before finding a new host where it can cause an infection (Fig. 1). By every second, its chances to replicate decrease due to removal by building ventilation, deposition on surfaces, or loss in infectivity. Thus, the transport of infectious viruses from the exhaled breath of one person to the inhaled air of another typically occurs within a few minutes. During this short time, the aerosol will undergo several transformations because of changing environmental conditions. Nevertheless, due to methodological challenges, we still have a remarkably limited understanding of the relationships between environmental factors and survival of pathogens in aerosols on short timescales. In a study in PNAS, Oswin et al. (1) show that the infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can decrease abruptly when aerosol particles move between environments. (Less)
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Proceedings of the National Academy of Sciences of the United States of America
volume
119
issue
29
article number
e2208742119
publisher
National Academy of Sciences
external identifiers
  • pmid:35858364
  • scopus:85134511901
ISSN
0027-8424
DOI
10.1073/pnas.2208742119
language
English
LU publication?
yes
id
f8371724-b7a6-4e28-9b8d-77880ddba173
date added to LUP
2022-08-26 15:29:53
date last changed
2024-04-18 03:18:38
@article{f8371724-b7a6-4e28-9b8d-77880ddba173,
  abstract     = {{A respiratory virus emitted in an aerosol particle will experience a tough journey with many obstacles before finding a new host where it can cause an infection (Fig. 1). By every second, its chances to replicate decrease due to removal by building ventilation, deposition on surfaces, or loss in infectivity. Thus, the transport of infectious viruses from the exhaled breath of one person to the inhaled air of another typically occurs within a few minutes. During this short time, the aerosol will undergo several transformations because of changing environmental conditions. Nevertheless, due to methodological challenges, we still have a remarkably limited understanding of the relationships between environmental factors and survival of pathogens in aerosols on short timescales. In a study in PNAS, Oswin et al. (1) show that the infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can decrease abruptly when aerosol particles move between environments.}},
  author       = {{Löndahl, Jakob and Alsved, Malin}},
  issn         = {{0027-8424}},
  language     = {{eng}},
  number       = {{29}},
  publisher    = {{National Academy of Sciences}},
  series       = {{Proceedings of the National Academy of Sciences of the United States of America}},
  title        = {{Abrupt decreases in infectivity of SARS-CoV-2 in aerosols}},
  url          = {{http://dx.doi.org/10.1073/pnas.2208742119}},
  doi          = {{10.1073/pnas.2208742119}},
  volume       = {{119}},
  year         = {{2022}},
}