Assessment of increased upper airway resistance in snorers. Methodological and diagnostic considerations.
(1997)- Abstract
- Sleep-related partial upper airway obstruction may cause increased morbidity and mortality, but diagnosis and treatment of patients is varying and inconsistent. The present studies were aimed to evaluate presently applied indirect methods for assessing respiratory ventilation and to investigate the value and accuracy in estimating upper airway resistance during sleep by measuring intrathoracic pressure variation with a microchip catheter in the esophagus.Furthermore, differential upper airway pressures and the relation between episodes of increased upper airway resistance and arousals were studied in subjects with habitual non-apneic snoring and daytime tiredness. During physical exercise in adults, the trend in changes of arterial... (More)
- Sleep-related partial upper airway obstruction may cause increased morbidity and mortality, but diagnosis and treatment of patients is varying and inconsistent. The present studies were aimed to evaluate presently applied indirect methods for assessing respiratory ventilation and to investigate the value and accuracy in estimating upper airway resistance during sleep by measuring intrathoracic pressure variation with a microchip catheter in the esophagus.Furthermore, differential upper airway pressures and the relation between episodes of increased upper airway resistance and arousals were studied in subjects with habitual non-apneic snoring and daytime tiredness. During physical exercise in adults, the trend in changes of arterial oxygenation was found to be relatively well revealed by continous transcutaneous measuring of PO2. Overnight studies did not reveal any significant difference in accuracy between transcutaneous measurement of SAO2 and PO2. Continous measurement of of intrathoracic pressure variat (Less)
- Abstract (Swedish)
- Popular Abstract in Swedish
Vid omhändertagande av patienter med snarkning och obstruktionsproblematik är det viktigt att beakta alla grader av andningsstörning. Nuvarande utredningsmetoder är väl lämpade för att diagnostisera avancerade sjukdomstillstånd präglade av andningsuppehåll under sömnen (apnéer) men har svårare att identifiera patienter vilkas andnings- och sömnstörning är mindre uttalad. Detta kan bero på allmänt använda undersökningsmtoders okänslighet för lindrigare störningar av andningen, men även den använda klassifikationen av andnings- och sömnstörningar kan tänkas vara för begränsad för att täcka hela sjukdomsspektrat. Avhandlingen visar att registrering av andningsreduktion med indirekta mätmetoder bör... (More) - Popular Abstract in Swedish
Vid omhändertagande av patienter med snarkning och obstruktionsproblematik är det viktigt att beakta alla grader av andningsstörning. Nuvarande utredningsmetoder är väl lämpade för att diagnostisera avancerade sjukdomstillstånd präglade av andningsuppehåll under sömnen (apnéer) men har svårare att identifiera patienter vilkas andnings- och sömnstörning är mindre uttalad. Detta kan bero på allmänt använda undersökningsmtoders okänslighet för lindrigare störningar av andningen, men även den använda klassifikationen av andnings- och sömnstörningar kan tänkas vara för begränsad för att täcka hela sjukdomsspektrat. Avhandlingen visar att registrering av andningsreduktion med indirekta mätmetoder bör granskas kritiskt, speciellt i de fall där diagnostik av obstruktiva andningsstörningar enbart baseras på dessa metoder. Intrathoracal tryckmätning i matstrupen har visats vara en bra metod för registrering av olika grader av andningsstörning av obstructiv typ. Med modern microchip teknik kan detta vara ett väsentlig (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/28977
- author
- Berg, Sören LU
- supervisor
- opponent
-
- Professor Ejnell, Hasse, ENT- dep. Sahlgrenska sjukhuset, Göteborg, Sweden.
- organization
- publishing date
- 1997
- type
- Thesis
- publication status
- published
- subject
- keywords
- arousals., pharyngeal pressure, intrathoracic pressure, hypopnea, respiratory ventilation, oxygenation, Non apneic snorers, upper airway obstruction, Otorhinolaryngology, audiology, auditive system and speech, Otorinolaryngologi, audiologi, hörsel- och talorganen
- pages
- 140 pages
- publisher
- Otorhinolaryngology (Lund)
- defense location
- Room F1 Main Building, University Hospital of Lund.
- defense date
- 1997-02-14 10:15:00
- external identifiers
-
- other:ISRN: LUMEDW/MERL--1042-SE
- language
- English
- LU publication?
- yes
- id
- f853d2c6-acde-42c7-b289-62729e2fce79 (old id 28977)
- date added to LUP
- 2016-04-04 10:12:30
- date last changed
- 2018-11-21 20:57:26
@phdthesis{f853d2c6-acde-42c7-b289-62729e2fce79,
abstract = {{Sleep-related partial upper airway obstruction may cause increased morbidity and mortality, but diagnosis and treatment of patients is varying and inconsistent. The present studies were aimed to evaluate presently applied indirect methods for assessing respiratory ventilation and to investigate the value and accuracy in estimating upper airway resistance during sleep by measuring intrathoracic pressure variation with a microchip catheter in the esophagus.Furthermore, differential upper airway pressures and the relation between episodes of increased upper airway resistance and arousals were studied in subjects with habitual non-apneic snoring and daytime tiredness. During physical exercise in adults, the trend in changes of arterial oxygenation was found to be relatively well revealed by continous transcutaneous measuring of PO2. Overnight studies did not reveal any significant difference in accuracy between transcutaneous measurement of SAO2 and PO2. Continous measurement of of intrathoracic pressure variat}},
author = {{Berg, Sören}},
keywords = {{arousals.; pharyngeal pressure; intrathoracic pressure; hypopnea; respiratory ventilation; oxygenation; Non apneic snorers; upper airway obstruction; Otorhinolaryngology; audiology; auditive system and speech; Otorinolaryngologi; audiologi; hörsel- och talorganen}},
language = {{eng}},
publisher = {{Otorhinolaryngology (Lund)}},
school = {{Lund University}},
title = {{Assessment of increased upper airway resistance in snorers. Methodological and diagnostic considerations.}},
year = {{1997}},
}