Fabrication and characterisation of a silicon-borosilicate glass microfluidic device for synchrotron-based hard X-ray spectroscopy studies
(2021) In RSC Advances 11(47). p.29859-29869- Abstract
Some of the most fundamental chemical building blocks of life on Earth are the metal elements. X-ray absorption spectroscopy (XAS) is an element-specific technique that can analyse the local atomic and electronic structure of, for example, the active sites in catalysts and energy materials and allow the metal sites in biological samples to be identified and understood. A microfluidic device capable of withstanding the intense hard X-ray beams of a 4th generation synchrotron and harsh chemical sample conditions is presented in this work. The device is evaluated at theK-edges of iron and bromine and theL3-edge of lead, in both transmission and fluorescence mode detection and in a wide range of sample concentrations, as low as... (More)
Some of the most fundamental chemical building blocks of life on Earth are the metal elements. X-ray absorption spectroscopy (XAS) is an element-specific technique that can analyse the local atomic and electronic structure of, for example, the active sites in catalysts and energy materials and allow the metal sites in biological samples to be identified and understood. A microfluidic device capable of withstanding the intense hard X-ray beams of a 4th generation synchrotron and harsh chemical sample conditions is presented in this work. The device is evaluated at theK-edges of iron and bromine and theL3-edge of lead, in both transmission and fluorescence mode detection and in a wide range of sample concentrations, as low as 0.001 M. The device is fabricated in silicon and glass with plasma etched microchannels defined in the silicon wafer before anodic bonding of the glass wafer into a complete device. The device is supported with a well-designed printed chip holder that made the microfluidic device portable and easy to handle. The chip holder plays a pivotal role in mounting the delicate microfluidic device on the beamline stage. Testing validated that the device was sufficiently robust to contain and flow through harsh acids and toxic samples. There was also no significant radiation damage to the device observed, despite focusing with intense X-ray beams for multiple hours. The quality of X-ray spectra collected is comparable to that from standard methods; hence we present a robust microfluidic device to analyse liquid samples using synchrotron XAS.
(Less)
- author
- organization
- publishing date
- 2021-08-26
- type
- Contribution to journal
- publication status
- published
- subject
- in
- RSC Advances
- volume
- 11
- issue
- 47
- pages
- 11 pages
- publisher
- Royal Society of Chemistry
- external identifiers
-
- scopus:85116496135
- pmid:35479529
- ISSN
- 2046-2069
- DOI
- 10.1039/d1ra05270e
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © The Royal Society of Chemistry 2021.
- id
- f96aa79d-b9c2-4184-a7d8-8cdfd4545a45
- date added to LUP
- 2021-10-21 09:34:23
- date last changed
- 2024-04-20 13:40:09
@article{f96aa79d-b9c2-4184-a7d8-8cdfd4545a45,
abstract = {{<p>Some of the most fundamental chemical building blocks of life on Earth are the metal elements. X-ray absorption spectroscopy (XAS) is an element-specific technique that can analyse the local atomic and electronic structure of, for example, the active sites in catalysts and energy materials and allow the metal sites in biological samples to be identified and understood. A microfluidic device capable of withstanding the intense hard X-ray beams of a 4th generation synchrotron and harsh chemical sample conditions is presented in this work. The device is evaluated at theK-edges of iron and bromine and theL<sub>3</sub>-edge of lead, in both transmission and fluorescence mode detection and in a wide range of sample concentrations, as low as 0.001 M. The device is fabricated in silicon and glass with plasma etched microchannels defined in the silicon wafer before anodic bonding of the glass wafer into a complete device. The device is supported with a well-designed printed chip holder that made the microfluidic device portable and easy to handle. The chip holder plays a pivotal role in mounting the delicate microfluidic device on the beamline stage. Testing validated that the device was sufficiently robust to contain and flow through harsh acids and toxic samples. There was also no significant radiation damage to the device observed, despite focusing with intense X-ray beams for multiple hours. The quality of X-ray spectra collected is comparable to that from standard methods; hence we present a robust microfluidic device to analyse liquid samples using synchrotron XAS.</p>}},
author = {{Micheal Raj, Pushparani and Barbe, Laurent and Andersson, Martin and De Albuquerque Moreira, Milena and Haase, Dörthe and Wootton, James and Nehzati, Susan and Terry, Ann E. and Friel, Ross J. and Tenje, Maria and Sigfridsson Clauss, Kajsa G.V.}},
issn = {{2046-2069}},
language = {{eng}},
month = {{08}},
number = {{47}},
pages = {{29859--29869}},
publisher = {{Royal Society of Chemistry}},
series = {{RSC Advances}},
title = {{Fabrication and characterisation of a silicon-borosilicate glass microfluidic device for synchrotron-based hard X-ray spectroscopy studies}},
url = {{http://dx.doi.org/10.1039/d1ra05270e}},
doi = {{10.1039/d1ra05270e}},
volume = {{11}},
year = {{2021}},
}