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Effects of III-V semiconductor nanowires on human lung cells

Abariute, L. LU and Prinz, C. N. LU (2018) 11th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 20th Annual Nanotech Conference and Expo,the 2018 SBIR/STTR Spring Innovation Conference, and the Defense TechConnect DTC Spring Conference 1. p.271-273
Abstract

Due to unique electronic and optical properties, semiconductor nanowires (NW) are widely used in various opto-electronic devices. Concerns have been raised about using NW since they share morphological similarities with nanofibers, such as carbon nanotubes and asbestos. However, the effects of NW exposure on humans remain unknown and there is a pressing need to assess any possible NW toxicity. During the NW development and large scale production, the most probable exposure route is inhalation. In this study, we subjected cultured human small airway epithelium (SAE) cells to epitaxial grown gallium phosphide (GaP) NW and assessed the NW uptake by the cells. We observed that SAE cells engulf NW, cells stay viable 7 days after exposure and... (More)

Due to unique electronic and optical properties, semiconductor nanowires (NW) are widely used in various opto-electronic devices. Concerns have been raised about using NW since they share morphological similarities with nanofibers, such as carbon nanotubes and asbestos. However, the effects of NW exposure on humans remain unknown and there is a pressing need to assess any possible NW toxicity. During the NW development and large scale production, the most probable exposure route is inhalation. In this study, we subjected cultured human small airway epithelium (SAE) cells to epitaxial grown gallium phosphide (GaP) NW and assessed the NW uptake by the cells. We observed that SAE cells engulf NW, cells stay viable 7 days after exposure and the NW remain inside the cells after cell division.

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author
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organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Human small airway epethelium cells, Nanowire uptake, Semiconductor nanowires, Toxicity
host publication
TechConnect Briefs 2018 - Advanced Materials
volume
1
pages
3 pages
publisher
TechConnect
conference name
11th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 20th Annual Nanotech Conference and Expo,the 2018 SBIR/STTR Spring Innovation Conference, and the Defense TechConnect DTC Spring Conference
conference location
Anaheim, United States
conference dates
2018-05-13 - 2018-05-16
external identifiers
  • scopus:85050802969
ISBN
9780998878225
language
English
LU publication?
yes
id
f99b789e-3e07-4b74-8c31-83c8afc080fd
date added to LUP
2018-09-24 14:07:17
date last changed
2023-09-08 06:50:30
@inproceedings{f99b789e-3e07-4b74-8c31-83c8afc080fd,
  abstract     = {{<p>Due to unique electronic and optical properties, semiconductor nanowires (NW) are widely used in various opto-electronic devices. Concerns have been raised about using NW since they share morphological similarities with nanofibers, such as carbon nanotubes and asbestos. However, the effects of NW exposure on humans remain unknown and there is a pressing need to assess any possible NW toxicity. During the NW development and large scale production, the most probable exposure route is inhalation. In this study, we subjected cultured human small airway epithelium (SAE) cells to epitaxial grown gallium phosphide (GaP) NW and assessed the NW uptake by the cells. We observed that SAE cells engulf NW, cells stay viable 7 days after exposure and the NW remain inside the cells after cell division.</p>}},
  author       = {{Abariute, L. and Prinz, C. N.}},
  booktitle    = {{TechConnect Briefs 2018 - Advanced Materials}},
  isbn         = {{9780998878225}},
  keywords     = {{Human small airway epethelium cells; Nanowire uptake; Semiconductor nanowires; Toxicity}},
  language     = {{eng}},
  month        = {{01}},
  pages        = {{271--273}},
  publisher    = {{TechConnect}},
  title        = {{Effects of III-V semiconductor nanowires on human lung cells}},
  volume       = {{1}},
  year         = {{2018}},
}