Health-related quality of life and supportive care needs in young adult cancer survivors—a longitudinal population-based study
(2024) In Supportive Care in Cancer 32(11).- Abstract
Purpose: To examine health-related quality of life (HRQoL) and supportive care needs among young adult (YA) cancer survivors up to 3 years post-diagnosis. Methods: A national cohort of individuals diagnosed at 18–39 years with breast, cervical, ovarian, or testicular cancer, lymphoma or brain tumor was approached with surveys at 1.5 (n = 1010, response rate 67%) and 3 (n = 722) years post-diagnosis. HRQoL was measured using the EORTC QLQ-C30. Scores were dichotomized using cut-off scores to predict supportive care needs in the Supportive Care Needs Survey-Long Form 59 (SCNS-LF59). Swedish cancer quality registers provided clinical data. Factors predicting need of support at 1.5 and 3 years post-diagnosis were identified using logistic... (More)
Purpose: To examine health-related quality of life (HRQoL) and supportive care needs among young adult (YA) cancer survivors up to 3 years post-diagnosis. Methods: A national cohort of individuals diagnosed at 18–39 years with breast, cervical, ovarian, or testicular cancer, lymphoma or brain tumor was approached with surveys at 1.5 (n = 1010, response rate 67%) and 3 (n = 722) years post-diagnosis. HRQoL was measured using the EORTC QLQ-C30. Scores were dichotomized using cut-off scores to predict supportive care needs in the Supportive Care Needs Survey-Long Form 59 (SCNS-LF59). Swedish cancer quality registers provided clinical data. Factors predicting need of support at 1.5 and 3 years post-diagnosis were identified using logistic regression. Results: HRQoL improvements over time were trivial to small. At both time points, a majority of respondents rated HRQoL levels indicating supportive care needs. At 1.5 years post-diagnosis, the risk of having support needs was lower among survivors with testicular cancer (compared to lymphoma) or university-level education, and higher among those on treatment (predominantly endocrine therapy). At 3 years post-diagnosis, when controlling for previous HRQoL scores, most correlations persisted, and poor self-rated household economy and chronic health conditions were additionally associated with supportive care needs. Conclusion: A majority of YAs diagnosed with cancer rate HRQoL at levels indicating support needs up to 3 years post-diagnosis. Testicular cancer survivors are at lower risk of having support needs. Concurrent health conditions and poor finances are linked to lower HRQoL. More efforts are needed to provide adequate, age-appropriate support to YA cancer survivors.
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- author
- Wide, Alexandra ; Ahlgren, Johan ; Smedby, Karin E. ; Hellman, Kristina ; Henriksson, Roger ; Ståhl, Olof LU ; Lampic, Claudia and Wettergren, Lena
- publishing date
- 2024-11
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Cancer, HRQoL, Psycho-oncology, Supportive care needs, Survivors, Young adult
- in
- Supportive Care in Cancer
- volume
- 32
- issue
- 11
- article number
- 742
- publisher
- Springer Science and Business Media B.V.
- external identifiers
-
- pmid:39436421
- scopus:85207235406
- ISSN
- 0941-4355
- DOI
- 10.1007/s00520-024-08896-3
- language
- English
- LU publication?
- no
- additional info
- Publisher Copyright: © The Author(s) 2024.
- id
- fa9d0c35-ef90-4030-83a9-f3e883f723f4
- date added to LUP
- 2024-12-18 09:19:19
- date last changed
- 2025-07-03 01:21:35
@article{fa9d0c35-ef90-4030-83a9-f3e883f723f4,
abstract = {{<p>Purpose: To examine health-related quality of life (HRQoL) and supportive care needs among young adult (YA) cancer survivors up to 3 years post-diagnosis. Methods: A national cohort of individuals diagnosed at 18–39 years with breast, cervical, ovarian, or testicular cancer, lymphoma or brain tumor was approached with surveys at 1.5 (n = 1010, response rate 67%) and 3 (n = 722) years post-diagnosis. HRQoL was measured using the EORTC QLQ-C30. Scores were dichotomized using cut-off scores to predict supportive care needs in the Supportive Care Needs Survey-Long Form 59 (SCNS-LF59). Swedish cancer quality registers provided clinical data. Factors predicting need of support at 1.5 and 3 years post-diagnosis were identified using logistic regression. Results: HRQoL improvements over time were trivial to small. At both time points, a majority of respondents rated HRQoL levels indicating supportive care needs. At 1.5 years post-diagnosis, the risk of having support needs was lower among survivors with testicular cancer (compared to lymphoma) or university-level education, and higher among those on treatment (predominantly endocrine therapy). At 3 years post-diagnosis, when controlling for previous HRQoL scores, most correlations persisted, and poor self-rated household economy and chronic health conditions were additionally associated with supportive care needs. Conclusion: A majority of YAs diagnosed with cancer rate HRQoL at levels indicating support needs up to 3 years post-diagnosis. Testicular cancer survivors are at lower risk of having support needs. Concurrent health conditions and poor finances are linked to lower HRQoL. More efforts are needed to provide adequate, age-appropriate support to YA cancer survivors.</p>}},
author = {{Wide, Alexandra and Ahlgren, Johan and Smedby, Karin E. and Hellman, Kristina and Henriksson, Roger and Ståhl, Olof and Lampic, Claudia and Wettergren, Lena}},
issn = {{0941-4355}},
keywords = {{Cancer; HRQoL; Psycho-oncology; Supportive care needs; Survivors; Young adult}},
language = {{eng}},
number = {{11}},
publisher = {{Springer Science and Business Media B.V.}},
series = {{Supportive Care in Cancer}},
title = {{Health-related quality of life and supportive care needs in young adult cancer survivors—a longitudinal population-based study}},
url = {{http://dx.doi.org/10.1007/s00520-024-08896-3}},
doi = {{10.1007/s00520-024-08896-3}},
volume = {{32}},
year = {{2024}},
}