Enantiomerically pure tetrahydrofuran compounds and a method for their preparation
Magnusson, Göran LU and Rehnberg, Nicola LU
(1989)
WO1989000160A1
- Abstract
- The present invention relates to novel enantiomerically pure intermediary compounds containing specifically substituted tetrahydrofuran structures as well as a method for preparing such intermediary compounds of formula (I), in which the carbon atom in the 2-position has (R)- or (S)-configuration; the substituents in the 2- and 3-positions are trans-related; the substituents in the 3- and 4-positions are cis- or trans-related; X is oxygen, sulphur or -SO2-; R1 is a sterically hindering protecting group; R2 is an organic residue; and the wavy line denotes a connection to the rest of the molecule; the method comprising reacting a compound containing partial formula (II), in which the carbon atom in the 2-position has... (More)
- The present invention relates to novel enantiomerically pure intermediary compounds containing specifically substituted tetrahydrofuran structures as well as a method for preparing such intermediary compounds of formula (I), in which the carbon atom in the 2-position has (R)- or (S)-configuration; the substituents in the 2- and 3-positions are trans-related; the substituents in the 3- and 4-positions are cis- or trans-related; X is oxygen, sulphur or -SO2-; R1 is a sterically hindering protecting group; R2 is an organic residue; and the wavy line denotes a connection to the rest of the molecule; the method comprising reacting a compound containing partial formula (II), in which the carbon atom in the 2-position has (R)- or (S)-configuration, and X, R1 and the wavy line are as defined above, with an organic anion R2-, where R2 is as defined above, as well as the compounds containing partial formula (I) themselves. The compounds preferably have formula (Ia), in which R3 is hydrogen or an organic residue and the stereochemistry and the other variables are as defined above. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/fb4556bb-38f7-496d-b4f6-0217f19ca35e
- inventor
- Magnusson, Göran
LU
and Rehnberg, Nicola
LU
- organization
- publishing date
- 1989-01-12
- type
- Patent
- publication status
- published
- subject
- publisher
- World Intellectual Property Organization
- patent number
- WO1989000160A1
- language
- English
- LU publication?
- yes
- additional info
- International Publication Number: WO8900160A1
- id
- fb4556bb-38f7-496d-b4f6-0217f19ca35e
- alternative location
- https://worldwide.espacenet.com/patent/search/family/008123233/publication/WO8900160A1?q=WO8900160A1
- date added to LUP
- 2021-10-21 08:45:13
- date last changed
- 2021-11-12 02:25:33
@misc{fb4556bb-38f7-496d-b4f6-0217f19ca35e,
abstract = {{The present invention relates to novel enantiomerically pure intermediary compounds containing specifically substituted tetrahydrofuran structures as well as a method for preparing such intermediary compounds of formula (I), in which the carbon atom in the 2-position has (R)- or (S)-configuration; the substituents in the 2- and 3-positions are trans-related; the substituents in the 3- and 4-positions are cis- or trans-related; X is oxygen, sulphur or -SO<sub>2</sub>-; R1 is a sterically hindering protecting group; R<sub>2</sub> is an organic residue; and the wavy line denotes a connection to the rest of the molecule; the method comprising reacting a compound containing partial formula (II), in which the carbon atom in the 2-position has (R)- or (S)-configuration, and X, R<sub>1</sub> and the wavy line are as defined above, with an organic anion R<sub>2</sub>-, where R<sub>2</sub> is as defined above, as well as the compounds containing partial formula (I) themselves. The compounds preferably have formula (Ia), in which R<sub>3</sub> is hydrogen or an organic residue and the stereochemistry and the other variables are as defined above.}},
author = {{Magnusson, Göran and Rehnberg, Nicola}},
language = {{eng}},
month = {{01}},
note = {{Patent, Patent Number: WO1989000160A1}},
publisher = {{World Intellectual Property Organization}},
title = {{Enantiomerically pure tetrahydrofuran compounds and a method for their preparation}},
url = {{https://worldwide.espacenet.com/patent/search/family/008123233/publication/WO8900160A1?q=WO8900160A1}},
year = {{1989}},
}