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The effect of systematic set-up deviations on the absorbed dose distribution for left-sided breast cancer treated with respiratory gating

Edvardsson, Anneli LU and Ceberg, Sofie LU (2013) 7th International Conference on 3D Radiation Dosimetry (IC3DDose) 444. p.012099-012099
Abstract
The aim of this study was 1) to investigate interfraction set-up uncertainties for patients treated with respiratory gating for left-sided breast cancer, 2) to investigate the effect of the inter-fraction set-up on the absorbed dose-distribution for the target and organs at risk (OARs) and 3) optimize the set-up correction strategy. By acquiring multiple set-up images the systematic set-up deviation was evaluated. The effect of the systematic set-up deviation on the absorbed dose distribution was evaluated by 1) simulation in the treatment planning system and 2) measurements with a biplanar diode array. The set-up deviations could be decreased using a no action level correction strategy. Not using the clinically implemented adaptive... (More)
The aim of this study was 1) to investigate interfraction set-up uncertainties for patients treated with respiratory gating for left-sided breast cancer, 2) to investigate the effect of the inter-fraction set-up on the absorbed dose-distribution for the target and organs at risk (OARs) and 3) optimize the set-up correction strategy. By acquiring multiple set-up images the systematic set-up deviation was evaluated. The effect of the systematic set-up deviation on the absorbed dose distribution was evaluated by 1) simulation in the treatment planning system and 2) measurements with a biplanar diode array. The set-up deviations could be decreased using a no action level correction strategy. Not using the clinically implemented adaptive maximum likelihood factor for the gating patients resulted in better set-up. When the uncorrected set-up deviations were simulated the average mean absorbed dose was increased from 1.38 to 2.21 Gy for the heart, 4.17 to 8.86 Gy to the left anterior descending coronary artery and 5.80 to 7.64 Gy to the left lung. Respiratory gating can induce systematic set-up deviations which would result in increased mean absorbed dose to the OARs if not corrected for and should therefore be corrected for by an appropriate correction strategy. (Less)
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author
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organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
7th International Conference on 3D Radiation Dosimetry (IC3DDose)
volume
444
pages
012099 - 012099
publisher
IOP Publishing
conference name
7th International Conference on 3D Radiation Dosimetry (IC3DDose)
conference location
Sydney, Australia
conference dates
2012-11-04 - 2012-11-08
external identifiers
  • wos:000322968600099
  • scopus:84883372500
ISSN
1742-6588
1742-6596
DOI
10.1088/1742-6596/444/1/012099
language
English
LU publication?
yes
id
fb694676-f108-4dda-b42a-a5f3d91925b1 (old id 4027078)
date added to LUP
2016-04-01 10:23:47
date last changed
2024-01-06 15:37:09
@inproceedings{fb694676-f108-4dda-b42a-a5f3d91925b1,
  abstract     = {{The aim of this study was 1) to investigate interfraction set-up uncertainties for patients treated with respiratory gating for left-sided breast cancer, 2) to investigate the effect of the inter-fraction set-up on the absorbed dose-distribution for the target and organs at risk (OARs) and 3) optimize the set-up correction strategy. By acquiring multiple set-up images the systematic set-up deviation was evaluated. The effect of the systematic set-up deviation on the absorbed dose distribution was evaluated by 1) simulation in the treatment planning system and 2) measurements with a biplanar diode array. The set-up deviations could be decreased using a no action level correction strategy. Not using the clinically implemented adaptive maximum likelihood factor for the gating patients resulted in better set-up. When the uncorrected set-up deviations were simulated the average mean absorbed dose was increased from 1.38 to 2.21 Gy for the heart, 4.17 to 8.86 Gy to the left anterior descending coronary artery and 5.80 to 7.64 Gy to the left lung. Respiratory gating can induce systematic set-up deviations which would result in increased mean absorbed dose to the OARs if not corrected for and should therefore be corrected for by an appropriate correction strategy.}},
  author       = {{Edvardsson, Anneli and Ceberg, Sofie}},
  booktitle    = {{7th International Conference on 3D Radiation Dosimetry (IC3DDose)}},
  issn         = {{1742-6588}},
  language     = {{eng}},
  pages        = {{012099--012099}},
  publisher    = {{IOP Publishing}},
  title        = {{The effect of systematic set-up deviations on the absorbed dose distribution for left-sided breast cancer treated with respiratory gating}},
  url          = {{http://dx.doi.org/10.1088/1742-6596/444/1/012099}},
  doi          = {{10.1088/1742-6596/444/1/012099}},
  volume       = {{444}},
  year         = {{2013}},
}