The effect of systematic set-up deviations on the absorbed dose distribution for left-sided breast cancer treated with respiratory gating
(2013) 7th International Conference on 3D Radiation Dosimetry (IC3DDose) 444. p.012099-012099- Abstract
- The aim of this study was 1) to investigate interfraction set-up uncertainties for patients treated with respiratory gating for left-sided breast cancer, 2) to investigate the effect of the inter-fraction set-up on the absorbed dose-distribution for the target and organs at risk (OARs) and 3) optimize the set-up correction strategy. By acquiring multiple set-up images the systematic set-up deviation was evaluated. The effect of the systematic set-up deviation on the absorbed dose distribution was evaluated by 1) simulation in the treatment planning system and 2) measurements with a biplanar diode array. The set-up deviations could be decreased using a no action level correction strategy. Not using the clinically implemented adaptive... (More)
- The aim of this study was 1) to investigate interfraction set-up uncertainties for patients treated with respiratory gating for left-sided breast cancer, 2) to investigate the effect of the inter-fraction set-up on the absorbed dose-distribution for the target and organs at risk (OARs) and 3) optimize the set-up correction strategy. By acquiring multiple set-up images the systematic set-up deviation was evaluated. The effect of the systematic set-up deviation on the absorbed dose distribution was evaluated by 1) simulation in the treatment planning system and 2) measurements with a biplanar diode array. The set-up deviations could be decreased using a no action level correction strategy. Not using the clinically implemented adaptive maximum likelihood factor for the gating patients resulted in better set-up. When the uncorrected set-up deviations were simulated the average mean absorbed dose was increased from 1.38 to 2.21 Gy for the heart, 4.17 to 8.86 Gy to the left anterior descending coronary artery and 5.80 to 7.64 Gy to the left lung. Respiratory gating can induce systematic set-up deviations which would result in increased mean absorbed dose to the OARs if not corrected for and should therefore be corrected for by an appropriate correction strategy. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4027078
- author
- Edvardsson, Anneli LU and Ceberg, Sofie LU
- organization
- publishing date
- 2013
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- 7th International Conference on 3D Radiation Dosimetry (IC3DDose)
- volume
- 444
- pages
- 012099 - 012099
- publisher
- IOP Publishing
- conference name
- 7th International Conference on 3D Radiation Dosimetry (IC3DDose)
- conference location
- Sydney, Australia
- conference dates
- 2012-11-04 - 2012-11-08
- external identifiers
-
- wos:000322968600099
- scopus:84883372500
- ISSN
- 1742-6588
- 1742-6596
- DOI
- 10.1088/1742-6596/444/1/012099
- language
- English
- LU publication?
- yes
- id
- fb694676-f108-4dda-b42a-a5f3d91925b1 (old id 4027078)
- date added to LUP
- 2016-04-01 10:23:47
- date last changed
- 2024-01-06 15:37:09
@inproceedings{fb694676-f108-4dda-b42a-a5f3d91925b1, abstract = {{The aim of this study was 1) to investigate interfraction set-up uncertainties for patients treated with respiratory gating for left-sided breast cancer, 2) to investigate the effect of the inter-fraction set-up on the absorbed dose-distribution for the target and organs at risk (OARs) and 3) optimize the set-up correction strategy. By acquiring multiple set-up images the systematic set-up deviation was evaluated. The effect of the systematic set-up deviation on the absorbed dose distribution was evaluated by 1) simulation in the treatment planning system and 2) measurements with a biplanar diode array. The set-up deviations could be decreased using a no action level correction strategy. Not using the clinically implemented adaptive maximum likelihood factor for the gating patients resulted in better set-up. When the uncorrected set-up deviations were simulated the average mean absorbed dose was increased from 1.38 to 2.21 Gy for the heart, 4.17 to 8.86 Gy to the left anterior descending coronary artery and 5.80 to 7.64 Gy to the left lung. Respiratory gating can induce systematic set-up deviations which would result in increased mean absorbed dose to the OARs if not corrected for and should therefore be corrected for by an appropriate correction strategy.}}, author = {{Edvardsson, Anneli and Ceberg, Sofie}}, booktitle = {{7th International Conference on 3D Radiation Dosimetry (IC3DDose)}}, issn = {{1742-6588}}, language = {{eng}}, pages = {{012099--012099}}, publisher = {{IOP Publishing}}, title = {{The effect of systematic set-up deviations on the absorbed dose distribution for left-sided breast cancer treated with respiratory gating}}, url = {{http://dx.doi.org/10.1088/1742-6596/444/1/012099}}, doi = {{10.1088/1742-6596/444/1/012099}}, volume = {{444}}, year = {{2013}}, }