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Safety of device closure of secundum atrial septal defects in children-does the weight at time of procedure matter?

Odermarsky, M. LU and Liuba, P. LU (2015) In Cardiology in the Young 25(Suppl. 1). p.61-61
Abstract
Background: Transcatheter closure of secundum atrial septal defect (ASD) is nowadays the main treatment option in many centers worldwide. In symptomatic infants or in those with certain comorbidities, there is a need for early intervention. Limited data are available about the procedural safety in infants below 15 kg of weight. Methods: Retrospective review of all patients referred to our center for ASD closure by device between January 1998 and November 2014. Major complications included death, cardiac or respiratory arrest, stroke, device embolization and erosion, need for emergency surgery or recatheterisation due to other procedure-related complications, significant pleural/pericardial effusion requiring intervention, persistent... (More)
Background: Transcatheter closure of secundum atrial septal defect (ASD) is nowadays the main treatment option in many centers worldwide. In symptomatic infants or in those with certain comorbidities, there is a need for early intervention. Limited data are available about the procedural safety in infants below 15 kg of weight. Methods: Retrospective review of all patients referred to our center for ASD closure by device between January 1998 and November 2014. Major complications included death, cardiac or respiratory arrest, stroke, device embolization and erosion, need for emergency surgery or recatheterisation due to other procedure-related complications, significant pleural/pericardial effusion requiring intervention, persistent arrhythmia or intraprocedural arrhythmia requiring cardioversion/ resuscitation, postprocedural significant valvular insufficiency or pulmonary vein obstruction, need for transfusion due to significant bleeding, and permanent vein thrombosis. Minor complications included transient arrhythmia, significant access site hematoma, transient vein thrombosis, transient limb paresthesis, and development of postprocedural infection occurring within 48 hours. Data were retrieved from the hospital's database and from the Swedish Registry for Congenital Heart Disease (Swedcon). Results: In total, 244 cases with age15 kg, there were 6 major (one death related to device erosion in a 17-year female with 26 mm ASD and absent retroaortic rim, surgical removal of device, arrhythmia requiring conversion in 2 patients, and need of transfusion) and 4 minor complications (transient arrhythmia). Conclusion: Transcatheter ASD closure appears to be safe and highly successful even in small infants. (Table Presented). (Less)
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
adverse device effect, cardioversion, cerebrovascular accident, child, complication, congenital heart disease, data base, death, device embolization, emergency surgery, female, heart arrest, heart arrhythmia, heart atrium septum defect, hematoma, hospital, human, infant, infection complication, limb, lung insufficiency, major clinical study, pericardial effusion, peroperative complication, pleura effusion, pulmonary hypertension, register, respiratory arrest, resuscitation, retrospective study, safety, surgery, vein occlusion, vein thrombosis
in
Cardiology in the Young
volume
25
issue
Suppl. 1
pages
1 pages
publisher
Cambridge University Press
ISSN
1467-1107
DOI
10.1017/S1047951115000529
language
English
LU publication?
no
id
fc234a46-1826-449f-9be5-eea73baa906e
date added to LUP
2017-10-22 15:34:17
date last changed
2017-10-24 08:54:06
@misc{fc234a46-1826-449f-9be5-eea73baa906e,
  abstract     = {Background: Transcatheter closure of secundum atrial septal defect (ASD) is nowadays the main treatment option in many centers worldwide. In symptomatic infants or in those with certain comorbidities, there is a need for early intervention. Limited data are available about the procedural safety in infants below 15 kg of weight. Methods: Retrospective review of all patients referred to our center for ASD closure by device between January 1998 and November 2014. Major complications included death, cardiac or respiratory arrest, stroke, device embolization and erosion, need for emergency surgery or recatheterisation due to other procedure-related complications, significant pleural/pericardial effusion requiring intervention, persistent arrhythmia or intraprocedural arrhythmia requiring cardioversion/ resuscitation, postprocedural significant valvular insufficiency or pulmonary vein obstruction, need for transfusion due to significant bleeding, and permanent vein thrombosis. Minor complications included transient arrhythmia, significant access site hematoma, transient vein thrombosis, transient limb paresthesis, and development of postprocedural infection occurring within 48 hours. Data were retrieved from the hospital's database and from the Swedish Registry for Congenital Heart Disease (Swedcon). Results: In total, 244 cases with age15 kg, there were 6 major (one death related to device erosion in a 17-year female with 26 mm ASD and absent retroaortic rim, surgical removal of device, arrhythmia requiring conversion in 2 patients, and need of transfusion) and 4 minor complications (transient arrhythmia). Conclusion: Transcatheter ASD closure appears to be safe and highly successful even in small infants. (Table Presented).},
  articleno    = {MP3-8},
  author       = {Odermarsky, M. and Liuba, P.},
  issn         = {1467-1107},
  keyword      = {adverse device effect,cardioversion,cerebrovascular accident,child,complication,congenital heart disease,data base,death,device embolization,emergency surgery,female,heart arrest,heart arrhythmia,heart atrium septum defect,hematoma,hospital,human,infant,infection complication,limb,lung insufficiency,major clinical study,pericardial effusion,peroperative complication,pleura effusion,pulmonary hypertension,register,respiratory arrest,resuscitation,retrospective study,safety,surgery,vein occlusion,vein thrombosis},
  language     = {eng},
  month        = {05},
  note         = {Conference Abstract},
  number       = {Suppl. 1},
  pages        = {61--61},
  publisher    = {Cambridge University Press},
  series       = {Cardiology in the Young},
  title        = {Safety of device closure of secundum atrial septal defects in children-does the weight at time of procedure matter?},
  url          = {http://dx.doi.org/10.1017/S1047951115000529},
  volume       = {25},
  year         = {2015},
}