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Pregnancy Complication History in 10-Year Cardiovascular Disease Risk Prediction: a Review of Recent Evidence

Gunnarsson, Ómar Sigurvin LU orcid and Timpka, Simon LU orcid (2019) In Current Epidemiology Reports 6. p.321-328
Abstract
Purpose of Review
Women with prevalent pregnancy complications (including preterm birth and preeclampsia) have twice the risk of later cardiovascular disease (CVD) compared to unaffected women. Current prevention guidelines recommend that reproductive history should be part of a woman’s CVD risk assessment. This review synthesizes recent findings on the value of history of pregnancy complications in 10-year CVD risk prediction.

Recent Findings
The associations between several pregnancy complications and CVD are still evident when conventional predictors are considered in middle age. However, comprehensive evaluation suggests that these associations translate into only minor, if any, clinically relevant improvements in... (More)
Purpose of Review
Women with prevalent pregnancy complications (including preterm birth and preeclampsia) have twice the risk of later cardiovascular disease (CVD) compared to unaffected women. Current prevention guidelines recommend that reproductive history should be part of a woman’s CVD risk assessment. This review synthesizes recent findings on the value of history of pregnancy complications in 10-year CVD risk prediction.

Recent Findings
The associations between several pregnancy complications and CVD are still evident when conventional predictors are considered in middle age. However, comprehensive evaluation suggests that these associations translate into only minor, if any, clinically relevant improvements in prediction.

Summary
Current evidence suggests that 10-year CVD risk prediction in women is not substantially improved by history of pregnancy complications. Future studies should identify subgroups to target with prevention efforts post-pregnancy. In the meantime, conventional models are appropriate for estimating 10-year CVD risk in women with a history of pregnancy complications. (Less)
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Current Epidemiology Reports
volume
6
pages
321 - 328
publisher
Springer Nature
ISSN
2196-2995
DOI
10.1007/s40471-019-00208-2
language
English
LU publication?
yes
id
fc977d77-4013-4edf-a17c-f02989dc306f
date added to LUP
2020-03-31 11:03:38
date last changed
2025-04-04 15:11:25
@article{fc977d77-4013-4edf-a17c-f02989dc306f,
  abstract     = {{Purpose of Review<br/>Women with prevalent pregnancy complications (including preterm birth and preeclampsia) have twice the risk of later cardiovascular disease (CVD) compared to unaffected women. Current prevention guidelines recommend that reproductive history should be part of a woman’s CVD risk assessment. This review synthesizes recent findings on the value of history of pregnancy complications in 10-year CVD risk prediction.<br/><br/>Recent Findings<br/>The associations between several pregnancy complications and CVD are still evident when conventional predictors are considered in middle age. However, comprehensive evaluation suggests that these associations translate into only minor, if any, clinically relevant improvements in prediction.<br/><br/>Summary<br/>Current evidence suggests that 10-year CVD risk prediction in women is not substantially improved by history of pregnancy complications. Future studies should identify subgroups to target with prevention efforts post-pregnancy. In the meantime, conventional models are appropriate for estimating 10-year CVD risk in women with a history of pregnancy complications.}},
  author       = {{Gunnarsson, Ómar Sigurvin and Timpka, Simon}},
  issn         = {{2196-2995}},
  language     = {{eng}},
  month        = {{07}},
  pages        = {{321--328}},
  publisher    = {{Springer Nature}},
  series       = {{Current Epidemiology Reports}},
  title        = {{Pregnancy Complication History in 10-Year Cardiovascular Disease Risk Prediction: a Review of Recent Evidence}},
  url          = {{http://dx.doi.org/10.1007/s40471-019-00208-2}},
  doi          = {{10.1007/s40471-019-00208-2}},
  volume       = {{6}},
  year         = {{2019}},
}