Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Taboo obsessions and their association with suicidality in obsessive-compulsive disorder

Cervin, Matti LU ; Conceição do Rosário, Maria ; Fontenelle, Leonardo ; Ferrão, Ygor ; Batistuzzo, Marcelo ; Albina, Torres ; Damiano, Rodolfo ; Fernández de la Cruz, Lorena ; Miguel, Euripedes C and Mataix-Cols, David (2022) In Journal of Psychiatric Research 154. p.117-122
Abstract
Individuals with obsessive-compulsive disorder (OCD) more often think about, attempt, and die by suicide than individuals from the general population. Sexual and religious obsessions (i.e., taboo obsessions) have been linked to increased risk of suicidality, but it is unclear if they explain additional risk over and above other risk factors. We refined the recently proposed multidimensional hierarchical model of OCD and explored how each symptom dimension in the model was associated with suicidality in a random half (n = 500) of a well-characterized cohort of patients with OCD. Symptom dimensions and other risk factors significantly associated with suicidality were included in a confirmatory multivariable model conducted with the other... (More)
Individuals with obsessive-compulsive disorder (OCD) more often think about, attempt, and die by suicide than individuals from the general population. Sexual and religious obsessions (i.e., taboo obsessions) have been linked to increased risk of suicidality, but it is unclear if they explain additional risk over and above other risk factors. We refined the recently proposed multidimensional hierarchical model of OCD and explored how each symptom dimension in the model was associated with suicidality in a random half (n = 500) of a well-characterized cohort of patients with OCD. Symptom dimensions and other risk factors significantly associated with suicidality were included in a confirmatory multivariable model conducted with the other half of the sample (n = 501). The predictive confirmatory model accounted for 19% of the variance in suicidality. Taboo obsessions, the general OCD factor (i.e., having many different OCD symptoms at the same time), lifetime major depression, and lifetime substance use disorders significantly predicted suicidality in this model. Lifetime major depression explained most unique variance in suicidality (5.6%) followed by taboo obsessions and the general OCD factor (1.9% each). Taboo obsessions explain a small but significant proportion of variance in suicidality and should be considered an independent risk factor for suicidality in patients with OCD. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Psychiatric Research
volume
154
pages
6 pages
publisher
Elsevier
external identifiers
  • scopus:85135384750
  • pmid:35933855
ISSN
1879-1379
DOI
10.1016/j.jpsychires.2022.07.044
language
English
LU publication?
yes
id
fcf529da-e85a-486a-b5b7-1ee3902453a2
date added to LUP
2022-07-31 11:32:33
date last changed
2024-02-18 01:46:49
@article{fcf529da-e85a-486a-b5b7-1ee3902453a2,
  abstract     = {{Individuals with obsessive-compulsive disorder (OCD) more often think about, attempt, and die by suicide than individuals from the general population. Sexual and religious obsessions (i.e., taboo obsessions) have been linked to increased risk of suicidality, but it is unclear if they explain additional risk over and above other risk factors. We refined the recently proposed multidimensional hierarchical model of OCD and explored how each symptom dimension in the model was associated with suicidality in a random half (n = 500) of a well-characterized cohort of patients with OCD. Symptom dimensions and other risk factors significantly associated with suicidality were included in a confirmatory multivariable model conducted with the other half of the sample (n = 501). The predictive confirmatory model accounted for 19% of the variance in suicidality. Taboo obsessions, the general OCD factor (i.e., having many different OCD symptoms at the same time), lifetime major depression, and lifetime substance use disorders significantly predicted suicidality in this model. Lifetime major depression explained most unique variance in suicidality (5.6%) followed by taboo obsessions and the general OCD factor (1.9% each). Taboo obsessions explain a small but significant proportion of variance in suicidality and should be considered an independent risk factor for suicidality in patients with OCD.}},
  author       = {{Cervin, Matti and Conceição do Rosário, Maria and Fontenelle, Leonardo and Ferrão, Ygor and Batistuzzo, Marcelo and Albina, Torres and Damiano, Rodolfo and Fernández de la Cruz, Lorena and Miguel, Euripedes C and Mataix-Cols, David}},
  issn         = {{1879-1379}},
  language     = {{eng}},
  month        = {{07}},
  pages        = {{117--122}},
  publisher    = {{Elsevier}},
  series       = {{Journal of Psychiatric Research}},
  title        = {{Taboo obsessions and their association with suicidality in obsessive-compulsive disorder}},
  url          = {{http://dx.doi.org/10.1016/j.jpsychires.2022.07.044}},
  doi          = {{10.1016/j.jpsychires.2022.07.044}},
  volume       = {{154}},
  year         = {{2022}},
}