A Proposal for the Performance, Classification, and Reporting of Lymph Node Fine-Needle Aspiration Cytopathology : The Sydney System
(2020) In Acta Cytologica 64(4). p.306-322- Abstract
BACKGROUND: The evaluation of lymph nodes (LN) by fine-needle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC. METHODS: The committee members prepared a document that has circulated among them five times; the final text has been approved by all the participants. It is based on a review of the international literature and on the expertise of the members. The system integrates clinical and imaging data with cytopathological features and ancillary techniques. The project has received the... (More)
BACKGROUND: The evaluation of lymph nodes (LN) by fine-needle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC. METHODS: The committee members prepared a document that has circulated among them five times; the final text has been approved by all the participants. It is based on a review of the international literature and on the expertise of the members. The system integrates clinical and imaging data with cytopathological features and ancillary techniques. The project has received the endorsement and patronage of the International Academy of Cytology and the European Federation of the Cytology Societies. RESULTS: Clinical, imaging, and serological data of lymphadenopathies, indications for LN-FNAC, technical procedures, and ancillary techniques are evaluated with specific recommendations. The reporting system includes two diagnostic levels. The first should provide basic diagnostic information and includes five categories: inadequate/insufficient, benign, atypical lymphoid cells of undetermined/uncertain significance, suspicious, and malignant. For each category, specific recommendations are provided. The second diagnostic level, when achievable, should produce the identification of specific benign or malignant entities and additional information by utilizing ancillary testing. CONCLUSION: The authors believe that the introduction of this system for performing and reporting LN-FNAC may improve the quality of the procedure, the report, and the communication between cytopathologists and the clinicians. This system may lead to a greater acceptance and utilization of LN-FNAC and to a better interdisciplinary understanding of the results of this procedure.
(Less)
- author
- organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Fine-needle aspiration cytology, Lymph node, Reporting system
- in
- Acta Cytologica
- volume
- 64
- issue
- 4
- pages
- 17 pages
- publisher
- Karger
- external identifiers
-
- pmid:32454496
- scopus:85088203711
- ISSN
- 0001-5547
- DOI
- 10.1159/000506497
- language
- English
- LU publication?
- yes
- id
- fdb14512-5989-4da4-9aba-9ca8627c9241
- date added to LUP
- 2020-07-31 08:15:05
- date last changed
- 2024-04-17 13:38:48
@article{fdb14512-5989-4da4-9aba-9ca8627c9241,
abstract = {{<p>BACKGROUND: The evaluation of lymph nodes (LN) by fine-needle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC. METHODS: The committee members prepared a document that has circulated among them five times; the final text has been approved by all the participants. It is based on a review of the international literature and on the expertise of the members. The system integrates clinical and imaging data with cytopathological features and ancillary techniques. The project has received the endorsement and patronage of the International Academy of Cytology and the European Federation of the Cytology Societies. RESULTS: Clinical, imaging, and serological data of lymphadenopathies, indications for LN-FNAC, technical procedures, and ancillary techniques are evaluated with specific recommendations. The reporting system includes two diagnostic levels. The first should provide basic diagnostic information and includes five categories: inadequate/insufficient, benign, atypical lymphoid cells of undetermined/uncertain significance, suspicious, and malignant. For each category, specific recommendations are provided. The second diagnostic level, when achievable, should produce the identification of specific benign or malignant entities and additional information by utilizing ancillary testing. CONCLUSION: The authors believe that the introduction of this system for performing and reporting LN-FNAC may improve the quality of the procedure, the report, and the communication between cytopathologists and the clinicians. This system may lead to a greater acceptance and utilization of LN-FNAC and to a better interdisciplinary understanding of the results of this procedure.</p>}},
author = {{Al-Abbadi, Mousa A. and Barroca, Helena and Bode-Lesniewska, Beata and Calaminici, Maria and Caraway, Nancy P. and Chhieng, David F. and Cozzolino, Immacolata and Ehinger, Mats and Field, Andrew S. and Geddie, William R. and Katz, Ruth L. and Lin, Oscar and Medeiros, L. Jeffrey and Monaco, Sara E. and Rajwanshi, Arvind and Schmitt, Fernando C. and Vielh, Philippe and Zeppa, Pio}},
issn = {{0001-5547}},
keywords = {{Fine-needle aspiration cytology; Lymph node; Reporting system}},
language = {{eng}},
number = {{4}},
pages = {{306--322}},
publisher = {{Karger}},
series = {{Acta Cytologica}},
title = {{A Proposal for the Performance, Classification, and Reporting of Lymph Node Fine-Needle Aspiration Cytopathology : The Sydney System}},
url = {{http://dx.doi.org/10.1159/000506497}},
doi = {{10.1159/000506497}},
volume = {{64}},
year = {{2020}},
}