Mecanismo de participación de los Enterovirus en la neuropatía epidémica. Hipótesis fisiopatológicas
(1997) In Revista cubana de medicina tropical 49(3). p.95-186- Abstract
During the epidemic neuropathy occurred in Cuba from 1992 to 1993, viral isolations antigenically connected with Coxsackie viruses were obtained from the cerebrospinal fluid of patients. Virological, epidemiological, toxicologic, nutritional, immunological and histopathological investigations were made. Though the disease was related to toxic and nutritional factors, it has been impossible to identify the cause of the epidemic. Taking into consideration the results of the different investigations, we have formulated a comprehensive and multifactorial hypothesis to explain the physiopathological mechanism of the participation of the isolated viruses as mediators in a process of autoimmunity of the pathogeny of the disease.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/ff3d73a6-98e6-4947-a695-1c7de64849d3
- author
- Más Lago, P ; Guzmán, M G ; Sarmiento Pérez, L LU ; Pérez, A B ; Alvarez, M ; Capó, V and Kourí, G
- alternative title
- Mechanism of Enterovirus participation in epidemic neuropathy. Physiopathological hypothesis
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Animals, Autoimmune Diseases/cerebrospinal fluid, Cerebrospinal Fluid/virology, Coxsackievirus Infections/complications, Cuba/epidemiology, Cytopathogenic Effect, Viral, Disease Outbreaks, Enterovirus/immunology, Humans, Interleukin-2/biosynthesis, Mice, Models, Biological, Molecular Mimicry, Nerve Tissue Proteins/immunology, Nutrition Disorders/complications, Optic Nerve Diseases/cerebrospinal fluid, Peripheral Nervous System Diseases/cerebrospinal fluid, Smoking/adverse effects, T-Lymphocyte Subsets/immunology, Viral Proteins/immunology, Virus Latency
- in
- Revista cubana de medicina tropical
- volume
- 49
- issue
- 3
- pages
- 10 pages
- publisher
- Editorial Ciencias Medicas
- external identifiers
-
- scopus:0031310657
- pmid:9685986
- ISSN
- 0375-0760
- language
- Spanish
- LU publication?
- no
- id
- ff3d73a6-98e6-4947-a695-1c7de64849d3
- alternative location
- http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0375-07601997000300006
- date added to LUP
- 2019-07-08 15:39:55
- date last changed
- 2024-01-01 15:48:37
@article{ff3d73a6-98e6-4947-a695-1c7de64849d3, abstract = {{<p>During the epidemic neuropathy occurred in Cuba from 1992 to 1993, viral isolations antigenically connected with Coxsackie viruses were obtained from the cerebrospinal fluid of patients. Virological, epidemiological, toxicologic, nutritional, immunological and histopathological investigations were made. Though the disease was related to toxic and nutritional factors, it has been impossible to identify the cause of the epidemic. Taking into consideration the results of the different investigations, we have formulated a comprehensive and multifactorial hypothesis to explain the physiopathological mechanism of the participation of the isolated viruses as mediators in a process of autoimmunity of the pathogeny of the disease.</p>}}, author = {{Más Lago, P and Guzmán, M G and Sarmiento Pérez, L and Pérez, A B and Alvarez, M and Capó, V and Kourí, G}}, issn = {{0375-0760}}, keywords = {{Animals; Autoimmune Diseases/cerebrospinal fluid; Cerebrospinal Fluid/virology; Coxsackievirus Infections/complications; Cuba/epidemiology; Cytopathogenic Effect, Viral; Disease Outbreaks; Enterovirus/immunology; Humans; Interleukin-2/biosynthesis; Mice; Models, Biological; Molecular Mimicry; Nerve Tissue Proteins/immunology; Nutrition Disorders/complications; Optic Nerve Diseases/cerebrospinal fluid; Peripheral Nervous System Diseases/cerebrospinal fluid; Smoking/adverse effects; T-Lymphocyte Subsets/immunology; Viral Proteins/immunology; Virus Latency}}, language = {{spa}}, number = {{3}}, pages = {{95--186}}, publisher = {{Editorial Ciencias Medicas}}, series = {{Revista cubana de medicina tropical}}, title = {{Mecanismo de participación de los Enterovirus en la neuropatía epidémica. Hipótesis fisiopatológicas}}, url = {{http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0375-07601997000300006}}, volume = {{49}}, year = {{1997}}, }